Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families

Gastroenterology

Volumn 151, Issue 4, 2016, Pages 698-709

  Levine, Adam P ^a   Pontikos, Nikolas ^a   Schiff, Elena R ^a   Jostins, Luke ^b   Speed, Doug ^a   Lovat, Laurence B ^a   Barrett, Jeffrey C ^c   Grasberger, Helmut ^d   Plagnol, Vincent ^a   Segal, Anthony W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Complex Disease; Inflammatory Bowel Disease; Pedigree; Population Isolate

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; ASHKENAZI JEW; COHORT ANALYSIS; CONTROLLED STUDY; CROHN DISEASE; CSF2RB GENE; DUOX2 GENE; EXOME; FAMILY STUDY; FEMALE; FRAMESHIFT MUTATION; GENE; GENE SEQUENCE; GENETIC RISK; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HUMAN; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ETHNOLOGY; GENETIC LINKAGE; GENETIC PREDISPOSITION; GENETICS; HEK293 CELL LINE; JEW; METABOLISM; MOLECULAR GENETICS; ONSET AGE; PEDIGREE; RISK FACTOR; YOUNG ADULT;

CD131 ANTIGEN; CSF2RB PROTEIN, HUMAN; DUOX2 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADOLESCENT; AGE OF ONSET; CROHN DISEASE; CYTOKINE RECEPTOR COMMON BETA SUBUNIT; EXOME; FEMALE; FRAMESHIFT MUTATION; GENETIC LINKAGE; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; JEWS; MALE; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NADPH OXIDASE; PEDIGREE; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS; YOUNG ADULT;

EID: 84989953192     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2016.06.040     Document Type: Article

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