ZEB1 induces LOXL2-mediated collagen stabilization and deposition in the extracellular matrix to drive lung cancer invasion and metastasis

Oncogene

Volumn 36, Issue 14, 2017, Pages 1925-1938

  Peng, D H ^a,b   Ungewiss, C ^a,b   Tong, P ^a   Byers, L A ^a   Wang, J ^a   Canales, J R ^a   Villalobos, P A ^a   Uraoka, N ^a   Mino, B ^a   Behrens, C ^a   Wistuba, I I ^a   Han, R I ^c   Wanna, C A ^c   Fahrenholtz, M ^c   Grande Allen, K J ^c   Creighton, C J ^a,d   Gibbons, D L ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c Rice University   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; LOX PROTEIN; LOXL2 PROTEIN; MICRORNA 200; PROTEIN; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; COLLAGEN; LOXL2 PROTEIN, HUMAN; OXIDOREDUCTASE; ZEB1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER PROGNOSIS; CELL MIGRATION; COLLAGEN METABOLISM; CONTROLLED STUDY; CROSS LINKING; ECTOPIC EXPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FOCAL ADHESION; HUMAN; HUMAN TISSUE; LUNG CANCER; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR INVASION; TUMOR MICROENVIRONMENT; ANIMAL; CELL CULTURE; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; LUNG TUMOR; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY;

AMINO ACID OXIDOREDUCTASES; ANIMALS; CELLS, CULTURED; COLLAGEN; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; LUNG NEOPLASMS; MALE; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; ZINC FINGER E-BOX-BINDING HOMEOBOX 1;

EID: 84989938682     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2016.358     Document Type: Article

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