Prehospital shock index and pulse pressure/heart rate ratio to predict massive transfusion after severe trauma: Retrospective analysis of a large regional trauma database

Journal of Trauma and Acute Care Surgery

Volumn 81, Issue 4, 2016, Pages 713-722

  Pottecher, Julien ^a,b   Ageron, François Xavier ^a,c   Fauché, Clémence ^a   Chemla, Denis ^a,e   Noll, Eric ^a,b   Duranteau, Jacques ^a,e   Chapiteau, Laurent ^a,d,f   Payen, Jean François ^a,g   Bouzat, Pierre ^a,b,g  

^a HÔPITAL DE HAUTEPIERRE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c Centre Hospitalier de la Region d'Annecy   (France)

^d HÔPITAL MICHALLON   (France)

^e BICÊTRE HOSPITAL   (France)

^f Centre hospitalier d'Albertville Moutiers   (France)

^g UNIV GRENOBLE ALPES   (France)

Author keywords

Arterial pressure; blood transfusion; decision support techniques; hemorrhagic shock; multiple trauma

Indexed keywords

ADULT; ARTICLE; BLOOD TRANSFUSION; BLUNT TRAUMA; CARDIOVASCULAR PARAMETERS; DIAGNOSTIC ACCURACY; ERYTHROCYTE; FEMALE; GLASGOW COMA SCALE; HEART HEMODYNAMICS; HEMORRHAGIC SHOCK; HUMAN; INJURY SCALE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; PULSE PRESSURE HEART RATE RATIO; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SHOCK; BLOOD PRESSURE; EMERGENCY HEALTH SERVICE; HEART RATE; HEMODYNAMICS; PATHOPHYSIOLOGY; PHYSIOLOGY; PREDICTIVE VALUE; REGISTER; SHOCK, HEMORRHAGIC; STATISTICS AND NUMERICAL DATA;

ADULT; BLOOD PRESSURE; BLOOD TRANSFUSION; EMERGENCY MEDICAL SERVICES; FEMALE; HEART RATE; HEMODYNAMICS; HUMANS; INJURY SEVERITY SCORE; MALE; PREDICTIVE VALUE OF TESTS; REGISTRIES; RETROSPECTIVE STUDIES; SHOCK, HEMORRHAGIC;

EID: 84989875905     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0000000000001191     Document Type: Article

References (49)

1. Kauvar DS, Lefering R, Wade CE. Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations. J Trauma. 2006;60(6 Suppl):S3-S11.
2. Tisherman SA, Schmicker RH, Brasel KJ, Bulger EM, Kerby JD, Minei JP, Powell JL, Reiff DA, Rizoli SB, Schreiber MA. Detailed description of all deaths in both the shock and traumatic brain injury hypertonic saline trials of the Resuscitation Outcomes Consortium. Ann Surg. 2015;261(3):586-590.
3. Spahn DR, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, Filipescu D, Hunt BJ, Komadina R, Nardi G, Neugebauer E, Ozier Y, Riddez L, Schultz A, Vincent JL, Rossaint R. Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care. 2013;17(2):R76.
4. Mann KG, Freeman K. TACTIC: Trans-agency Consortium for Trauma-Induced Coagulopathy. J Thromb Haemost. 2015;13(Suppl 1):S63-S71.
5. Holcomb JB, del Junco DJ, Fox EE, Wade CE, Cohen MJ, Schreiber MA, Alarcon LH, Bai Y, Brasel KJ, Bulger EM, Cotton BA, Matijevic N, Muskat P, Myers JG, Phelan HA, White CE, Zhang J, Rahbar MH; PROMMTT Study Group. The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks. JAMA Surg. 2013;148 (2):127-136.
6. Kotwal RS, Howard JT, Orman JA, Tarpey BW, Bailey JA, Champion HR, Mabry RL, Holcomb JB, Gross KR. The effect of a golden hour policy on themorbidity andmortality of combat casualties. JAMA Surg. 2015;30:1-10.
7. Waters JH. Role of the massive transfusion protocol in the management of haemorrhagic shock. Br J Anaesth. 2014;113(Suppl 2):ii8-ii3.
8. CamazineMN, HemmilaMR, Leonard JC, Jacobs RA, Horst JA, Kozar RA, Bochicchio GV, Nathens AB, Cryer HM, Spinella PC. Massive transfusion policies at trauma centers participating in the American College of Surgeons Trauma Quality Improvement Program. J Trauma Acute Care Surg. 2015;78(6 Suppl 1):S48-S53.
9. Vogt KN, Van Koughnett JA, Dubois L, Gray DK, Parry NG. The use of trauma transfusion pathways for blood component transfusion in the civilian population: a systematic review and meta-analysis. Transfus Med. 2012;22(3):156-166.
10. Dente CJ, Shaz BH, Nicholas JM, Harris RS, Wyrzykowski AD, Patel S, Shah A, Vercruysse GA, Feliciano DV, Rozycki GS, Salomone JP, Ingram WL. Improvements in early mortality and coagulopathy are sustained better in patients with blunt trauma after institution of a massive transfusion protocol in a civilian Level I trauma center. J Trauma. 2009;66 (6):1616-1624.
11. Radwan ZA, Bai Y, Matijevic N, del Junco DJ, McCarthy JJ, Wade CE, Holcomb JB, Cotton BA. An emergency department thawed plasma protocol for severely injured patients. JAMA Surg. 2013;148(2):170-175.
12. Yücel N, Lefering R, Maegele M, Vorweg M, Tjardes T, Ruchholtz S, Neugebauer EA, Wappler F, Bouillon B, Rixen D; Polytrauma Study Group of the German Trauma Society. Trauma Associated Severe Hemorrhage (TASH) score: probability of mass transfusion as surrogate for life threatening hemorrhage after multiple trauma. J Trauma. 2006;60 (6):1228-1236.
13. Nunez TC, Voskresensky IV, Dossett LA, Shinall R, DuttonWD, Cotton BA. Early prediction of massive transfusion in trauma: simple as ABC (Assessment of Blood Consumption)? J Trauma. 2009;66(2):346-352.
14. McDaniel LM, Etchill EW, Raval JS, Neal MD. State of the art: massive transfusion. Transfus Med. 2014;24(3):138-144.
15. Mutschler M, Nienaber U, Münzberg M, Wölfl C, Schoechl H, Paffrath T, Bouillon B, Maegele M. The Shock Index revisited-a fast guide to transfusion requirement? A retrospective analysis on 21, 853 patients derived from the TraumaRegister DGU. Crit Care. 2013;17(4):R172.
16. Pottecher J, Chemla D, Xavier L, Liu N, Chazot T, Marescaux J, Fischler M, Diemunsch P, Duranteau J. The pulse pressure/heart rate ratio as a marker of stroke volume changes during hemorrhagic shock and resuscitation in anesthetized swine. J Trauma Acute Care Surg. 2013;74(6):1438-1445.
17. Convertino VA, Ryan KL, Rickards CA, Salinas J, McManus JG, Cooke WH, Holcomb JB. Physiological and medical monitoring for en route care of combat casualties. J Trauma. 2008;64(4 Suppl):S342-S353.
18. Bouzat P, Ageron FX, Brun J, Levrat A, Berthet M, Rancurel E, Thouret JM, Thony F, Arvieux C, Payen JF; TRENAU group. A regional trauma system to optimize the pre-hospital triage of trauma patients. Crit Care. 2015;19(1):111.
19. Sasser SM, Hunt RC, Faul M, Sugerman D, Pearson WS, Dulski T, Wald MM, Jurkovich GJ, Newgard CD, Lerner EB; Centers for Disease Control and Prevention (CDC). Guidelines for field triage of injured patients: recommendations of the National Expert Panel on Field Triage, 2011. MMWR Recomm Rep. 2012;61(RR-1):1-20.
20. Hamada SR, Gauss T, Duchateau FX, Truchot J, Harrois A, Raux M, Duranteau J, Mantz J, Paugam-Burtz C. Evaluation of the performance of French physician-staffed emergency medical service in the triage of major trauma patients. J Trauma Acute Care Surg. 2014;76(6):1476-1483.
21. Ringdal KG, Coats TJ, Lefering R, Di Bartolomeo S, Steen PA, Røise O, Handolin L, Lossius HM; Utstein TCD expert panel. The Utstein template for uniform reporting of data following major trauma: a joint revision by SCANTEM, TARN, DGU-TR and RITG. Scand J Trauma Resusc Emerg Med. 2008;16:7.
22. Bossuyt PM, Reitsma JB, Bruns DE, Gatsonis CA, Glasziou PP, Irwig L, Lijmer JG, Moher D, Rennie D, de Vet HC, Kressel HY, Rifai N, Golub RM, Altman DG, Hooft L, Korevaar DA, Cohen JF; STARD Group. STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies. BMJ. 2015;351:h5527.
23. DeMuro JP, Simmons S, Jax J, Gianelli SM. Application of the shock index to the prediction of need for hemostasis intervention. Am J Emerg Med. 2013;31(8):1260-1263.
24. Vandromme MJ, Griffin RL, Kerby JD, McGwin G Jr, Rue LW, Weinberg JA. Identifying risk for massive transfusion in the relatively normotensive patient: utility of the prehospital shock index. J Trauma. 2011;70(2):384-388;discussion 388-390.
25. Hsu JM, Hitos K, Fletcher JP. Identifying the bleeding trauma patient: predictive factors for massive transfusion in an Australasian trauma population. J Trauma Acute Care Surg. 2013;75(3):359-364.
26. Savage SA, Zarzaur BL, Croce MA, Fabian TC. Redefining massive transfusion when every second counts. J Trauma Acute Care Surg. 2013;74 (2):396-400.
27. Mitra B, Cameron PA, Gruen RL, Mori A, Fitzgerald M, Street A. The definition of massive transfusion in trauma: a critical variable in examining evidence for resuscitation. Eur J Emerg Med. 2011;18(3):137-142.
28. Savage SA, Sumislawski JJ, Zarzaur BL, DuttonWP, CroceMA, Fabian TC. The new metric to define large-volume hemorrhage: results of a prospective study of the critical administration threshold. J Trauma Acute Care Surg. 2015;78(2):224-229.
29. Zatta AJ, McQuilten ZK, Mitra B, Roxby DJ, Sinha R, Whitehead S, Dunkley S, Kelleher S, Hurn C, Cameron PA, Isbister JP, Wood EM, Phillips LE; Massive Transfusion Registry Steering Committee. Elucidating the clinical characteristics of patients captured using different definitions of massive transfusion. Vox Sang. 2014 Jul;107(1):60-70.
30. Bouzat P, Broux C, Ageron FX, Thony F, Arvieux C, Tonetti J, Gay E, Rancurel E, Payen JF. Trauma network for severely injured patients. Ann Fr Anesth Reanim. 2013;32(7-8):531-534.
31. Kaji AH, Schriger D, Green S. Looking through the retrospectoscope: reducing bias in emergency medicine chart review studies. Ann Emerg Med. 2014;64(3):292-298.
32. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988;44(3):837-845.
33. Ray P, LeManach Y, Riou B, Houle TT. Statistical evaluation of a biomarker. Anesthesiology. 2010;112(4):1023-1040.
34. Biais M, Ehrmann S, Mari A, Conte B, Mahjoub Y, Desebbe O, Pottecher J, Lakhal K, Benzekri-Lefevre D, Molinari N, Boulain T, Lefrant JY, Muller L; AzuRea Group. Clinical relevance of pulse pressure variations for predicting fluid responsiveness in mechanically ventilated intensive care unit patients: the grey zone approach. Crit Care. 2014;18(6):1-11.
35. Ogura T, NakanoM, Izawa Y, NakamuraM, Fujizuka K, Lefor AT. Analysis of risk classification for massive transfusion in severe trauma using the gray zone approach. Am J Emerg Med. 2015;33(9):1146-1151.
36. Izzo JL Jr. Brachial vs. central systolic pressure and pulse wave transmission indicators: a critical analysis. Am J Hypertens. 2014;27(12):1433-1442.
37. Chemla D, Hébert JL, Coirault C, Zamani K, Suard I, Colin P, Lecarpentier Y. Total arterial compliance estimated by stroke volume-to-aortic pulse pressure ratio in humans. Am J Physiol. 1998;274(2 Pt 2):H500-H505.
38. Campbell R, ArdaghMW, ThanM. Validation of the pulse rate over pressure evaluation index as a detector of early occult hemorrhage: a prospective observational study. J Trauma Acute Care Surg. 2012;73(1):286-288.
39. Sohn CH, Kim WY, Kim SR, Seo DW, Ryoo SM, Lee YS, Lee JH, Oh BJ, Won HS, Shim JY, et al. An increase in initial shock index is associated with the requirement for massive transfusion in emergency department patients with primary postpartum hemorrhage. Shock. 2013;40(2):101-105.
40. Olaussen A, Peterson EL, Mitra B, O'Reilly G, Jennings PA, Fitzgerald M. Massive transfusion prediction with inclusion of the pre-hospital shock index. Injury. 2015;46(5):822-826.
41. Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, del Junco DJ, Brasel KJ, Bulger EM, Callcut RA, Cohen MJ, Cotton BA, Fabian TC, Inaba K, Kerby JD, Muskat P, O'Keeffe T, Rizoli S, Robinson BR, Scalea TM, Schreiber MA, Stein DM, Weinberg JA, Callum JL, Hess JR, Matijevic N, Miller CN, Pittet JF, Hoyt DB, Pearson GD, Leroux B, van Belle G; PROPPR Study Group. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial. JAMA. 2015;313(5):471-482.
42. Schöchl H, Voelckel W, Schlimp CJ. Management of traumatic haemorrhage-the European perspective. Anaesthesia. 2014 1;70:102-137.
43. Stanworth SJ, Davenport R, Curry N, Seeney F, Eaglestone S, Edwards A, Martin K, Allard S, Woodford M, Lecky FE, Brohi K. Mortality from trauma haemorrhage and opportunities for improvement in transfusion practice. Br J Surg. 2016;103(4):357-365.
44. Bawazeer M, Ahmed N, Izadi H, McFarlan A, Nathens A, Pavenski K. Compliance with a massive transfusion protocol (MTP) impacts patient outcome. Injury. 2015;46(1):21-28.
45. Cotton BA, Dossett LA, Au BK, Nunez TC, Robertson AM, Young PP. Room for (performance) improvement: provider-related factors associated with poor outcomes in massive transfusion. J Trauma. 2009;67(5):1004-1012.
46. Trickey AW, Fox EE, Del Junco DJ, Ning J, Holcomb JB, Brasel KJ, Cohen MJ, SchreiberMA, Bulger EM, Phelan HA, Alarcon LH, Myers JG, Muskat P, Cotton BA, Wade CE, RahbarMH; PROMMTT Study Group. The impact of missing trauma data on predicting massive transfusion. J Trauma Acute Care Surg. 2013;75(Suppl 1):S68-S74.
47. Rogers A, Rogers F, Bradburn E, Krasne M, Lee J, Wu D, Edavettal M, Horst M. Old and undertriaged: a lethal combination. Am Surg. 2012;78(6):711-715.
48. Galvagno SM, Haut ER, Zafar SN, Millin MG, Efron DT, Koenig GJ Jr, Baker SP, Bowman SM, Pronovost PJ, Haider AH. Association between helicopter vs ground emergency medical services and survival for adults with major trauma. JAMA. 2012;307(15):1602-1610.
49. Le ManachY, Hofer CK, Lehot JJ, Vallet B, Goarin JP, Tavernier B, Cannesson M. Can changes in arterial pressure be used to detect changes in cardiac output during volume expansion in the perioperative period? Anesthesiology. 2012; 117(6):1165-1174.