Coculture with astrocytes reduces the radiosensitivity of glioblastoma stem-like cells and identifies additional targets for radiosensitization

Cancer Medicine

Volumn 4, Issue 11, 2015, Pages 1705-1716

  Rath, Barbara H ^a   Wahba, Amy ^a   Camphausen, Kevin ^a   Tofilon, Philip J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Astrocytes; Glioblastoma stem like cells; Microenvironment; Radiosensitization; STAT3

Indexed keywords

3 (6 BROMO 2 PYRIDINYL) 2 CYANO N (1 PHENYLETHYL)ACRYLAMIDE; JANUS KINASE; STAT3 PROTEIN; CYTOKINE; HISTONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CANCER RADIOTHERAPY; CANCER STEM CELL; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; DRUG EFFECT; FEMALE; GENE EXPRESSION PROFILING; GLIOBLASTOMA; IN VITRO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RADIATION RESPONSE; RADIOSENSITIVITY; RADIOSENSITIZATION; TUMOR MICROENVIRONMENT; ANIMAL; BRAIN TUMOR; CLUSTER ANALYSIS; DISEASE MODEL; DRUG SCREENING; GENETICS; HUMAN; METABOLISM; RADIATION TOLERANCE; TUMOR CELL LINE;

ANIMALS; ASTROCYTES; BRAIN NEOPLASMS; CELL LINE, TUMOR; CLUSTER ANALYSIS; COCULTURE TECHNIQUES; CYTOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; GENE EXPRESSION PROFILING; GLIOBLASTOMA; HISTONES; HUMANS; MICE; NEOPLASTIC STEM CELLS; RADIATION TOLERANCE; STAT3 TRANSCRIPTION FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84989778407     PISSN: None     EISSN: 20457634     Source Type: Journal    
DOI: 10.1002/cam4.510     Document Type: Article

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