Identifying small molecules which inhibit autophagy: A phenotypic screen using image-based high-content cell analysis

Current Chemical Genomics and Translational Medicine

Volumn 8, Issue , 2014, Pages 3-15

  Peppard, J V ^a   Rugg, C ^a   Smicker, M ^a   Dureuil, C ^b   Ronan, B ^b   Flamand, O ^b   Durand, L ^b   Pasquier, B ^b  

^a Lead Generation to Candidate Realization   (United States)

^b SANOFI   (France)

Author keywords

Autophagy; High content screening; HTS; Image based screening; Inhibitors; LC3; Phenotypic screening

Indexed keywords

ARTICLE; AUTOPHAGY; BIOLOGICAL ACTIVITY; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; FLOW CYTOMETRY; GENE EXPRESSION; HELA CELL LINE; HUMAN; HUMAN CELL; METABOLIC STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE CELL ANALYSIS;

EID: 84989247251     PISSN: None     EISSN: 22139885     Source Type: Journal    
DOI: 10.2174/2213988501408010003     Document Type: Article

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