메뉴 건너뛰기




Volumn 60, Issue 11, 2016, Pages 2379-2386

Does epicatechin contribute to the acute vascular function effects of dark chocolate? A randomized, crossover study

Author keywords

Chocolate; Epicatechin; Flavan 3 ol; Randomized controlled trial; Vascular function

Indexed keywords

CATECHIN; FLAVAN-3-OL; FLAVONOID;

EID: 84989216749     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201600045     Document Type: Article
Times cited : (30)

References (28)
  • 1
    • 80053389356 scopus 로고    scopus 로고
    • Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis
    • Buitrago-Lopez, A., Sanderson, J., Johnson, L., Warnakula, S. et al., Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis. BMJ 2011, 343, 7825.
    • (2011) BMJ , vol.343 , pp. 7825
    • Buitrago-Lopez, A.1    Sanderson, J.2    Johnson, L.3    Warnakula, S.4
  • 3
    • 84857892715 scopus 로고    scopus 로고
    • Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials
    • Hooper, L., Kay, C., Abdelhamid, A., Kroon, P. A. et al., Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am. J. Clin. Nutr. 2012, 95, 740–751.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 740-751
    • Hooper, L.1    Kay, C.2    Abdelhamid, A.3    Kroon, P.A.4
  • 4
    • 84899522823 scopus 로고    scopus 로고
    • Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men
    • Esser, D., Mars, M., Oosterink, E., Stalmach, A. et al., Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men. FASEB J. 2014, 28, 1464–1473.
    • (2014) FASEB J. , vol.28 , pp. 1464-1473
    • Esser, D.1    Mars, M.2    Oosterink, E.3    Stalmach, A.4
  • 6
    • 84920935054 scopus 로고    scopus 로고
    • Cocoa consumption dose-dependently improves flow-mediated dilation and arterial stiffness decreasing blood pressure in healthy individuals
    • Grassi, D., Desideri, G., Necozione, S., Di Giosia, P. et al., Cocoa consumption dose-dependently improves flow-mediated dilation and arterial stiffness decreasing blood pressure in healthy individuals. J. Hypertens. 2015, 33, 294–303.
    • (2015) J. Hypertens. , vol.33 , pp. 294-303
    • Grassi, D.1    Desideri, G.2    Necozione, S.3    Di Giosia, P.4
  • 7
    • 84859048094 scopus 로고    scopus 로고
    • Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans
    • Ottaviani, J. I., Kwik-Uribe, C., Keen, C. L., Schroeter, H. Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans. Am. J. Clin. Nutr. 2012, 95, 851–858.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 851-858
    • Ottaviani, J.I.1    Kwik-Uribe, C.2    Keen, C.L.3    Schroeter, H.4
  • 8
    • 32244437985 scopus 로고    scopus 로고
    • (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
    • Schroeter, H., Heiss, C., Balzer, J., Kleinbongard, P. et al., (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proc. Natl. Acad. Sci. USA. 2006, 103, 1024–1029.
    • (2006) Proc. Natl. Acad. Sci. USA. , vol.103 , pp. 1024-1029
    • Schroeter, H.1    Heiss, C.2    Balzer, J.3    Kleinbongard, P.4
  • 9
    • 53849146739 scopus 로고    scopus 로고
    • Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men
    • Loke, W. M., Hodgson, J. M., Proudfoot, J. M., McKinley, A. J. et al., Pure dietary flavonoids quercetin and (-)-epicatechin augment nitric oxide products and reduce endothelin-1 acutely in healthy men. Am. J. Clin. Nutr. 2008, 88, 1018–1025.
    • (2008) Am. J. Clin. Nutr. , vol.88 , pp. 1018-1025
    • Loke, W.M.1    Hodgson, J.M.2    Proudfoot, J.M.3    McKinley, A.J.4
  • 10
    • 84929657335 scopus 로고    scopus 로고
    • Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial
    • Dower, J. I., Geleijnse, J. M., Gijsbers, L., Zock, P. L. et al., Effects of the pure flavonoids epicatechin and quercetin on vascular function and cardiometabolic health: a randomized, double-blind, placebo-controlled, crossover trial. Am. J. Clin. Nutr. 2015, 101, 914–921.
    • (2015) Am. J. Clin. Nutr. , vol.101 , pp. 914-921
    • Dower, J.I.1    Geleijnse, J.M.2    Gijsbers, L.3    Zock, P.L.4
  • 11
    • 84920859921 scopus 로고    scopus 로고
    • Flavan-3-ols, theobromine, and the effects of cocoa and chocolate on cardiometabolic risk factors
    • Berends, L. M., van der Velpen, V., Cassidy, A., Flavan-3-ols, theobromine, and the effects of cocoa and chocolate on cardiometabolic risk factors. Curr. Opin. Lipidol. 2015, 26, 10–19.
    • (2015) Curr. Opin. Lipidol. , vol.26 , pp. 10-19
    • Berends, L.M.1    van der Velpen, V.2    Cassidy, A.3
  • 12
    • 84879770748 scopus 로고    scopus 로고
    • Bioavailability of epicatechin and effects on nitric oxide metabolites of an apple flavanol-rich extract supplemented beverage compared to a whole apple puree: a randomized, placebo-controlled, crossover trial
    • Hollands, W. J., Hart, D. J., Dainty, J. R., Hasselwander, O. et al., Bioavailability of epicatechin and effects on nitric oxide metabolites of an apple flavanol-rich extract supplemented beverage compared to a whole apple puree: a randomized, placebo-controlled, crossover trial. Mol. Nutr. Food Res. 2013, 57, 1209–1217.
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1209-1217
    • Hollands, W.J.1    Hart, D.J.2    Dainty, J.R.3    Hasselwander, O.4
  • 13
    • 0027460281 scopus 로고
    • An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man
    • Karamanoglu, M., O'Rourke, M. F., Avolio, A. P., Kelly, R. P., An analysis of the relationship between central aortic and peripheral upper limb pressure waves in man. Eur. Heart J. 1993, 14, 160–167.
    • (1993) Eur. Heart J. , vol.14 , pp. 160-167
    • Karamanoglu, M.1    O'Rourke, M.F.2    Avolio, A.P.3    Kelly, R.P.4
  • 14
    • 0035724737 scopus 로고    scopus 로고
    • Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform
    • Pauca, A. L., O'Rourke, M. F., Kon, N. D., Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform. Hypertension 2001, 38, 932–937.
    • (2001) Hypertension , vol.38 , pp. 932-937
    • Pauca, A.L.1    O'Rourke, M.F.2    Kon, N.D.3
  • 15
    • 69949116426 scopus 로고    scopus 로고
    • Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro
    • Appeldoorn, M. M., Venema, D. P., Peters, T. H. F., Koenen, M. E. et al., Some phenolic compounds increase the nitric oxide level in endothelial cells in vitro. J. Agric. Food Chem. 2009, 57, 7693–7699.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 7693-7699
    • Appeldoorn, M.M.1    Venema, D.P.2    Peters, T.H.F.3    Koenen, M.E.4
  • 16
    • 84860300744 scopus 로고    scopus 로고
    • Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability
    • Saha, S., Hollands, W., Needs, P. W., Ostertag, L. M. et al., Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability. Pharmacol. Res. 2012, 65, 592–602.
    • (2012) Pharmacol. Res. , vol.65 , pp. 592-602
    • Saha, S.1    Hollands, W.2    Needs, P.W.3    Ostertag, L.M.4
  • 17
    • 18144377085 scopus 로고    scopus 로고
    • Impaired progenitor cell activity in age-related endothelial dysfunction
    • Heiss, C., Keymel, S., Niesler, U., Ziemann, J. et al., Impaired progenitor cell activity in age-related endothelial dysfunction. J. Am. Coll. Cardiol. 2005, 45, 1441–1448.
    • (2005) J. Am. Coll. Cardiol. , vol.45 , pp. 1441-1448
    • Heiss, C.1    Keymel, S.2    Niesler, U.3    Ziemann, J.4
  • 18
    • 84930226092 scopus 로고    scopus 로고
    • Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial
    • Heiss, C., Sansone, R., Karimi, H., Krabbe, M. et al., Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial. Age 2015, 37, 56.
    • (2015) Age , vol.37 , pp. 56
    • Heiss, C.1    Sansone, R.2    Karimi, H.3    Krabbe, M.4
  • 19
    • 84938500112 scopus 로고    scopus 로고
    • Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects
    • Rodriguez-Mateos, A., Cifuentes-Gomez, T., Gonzalez-Salvador, I., Ottaviani, J. I. et al., Influence of age on the absorption, metabolism, and excretion of cocoa flavanols in healthy subjects. Mol. Nutr. Food Res. 2015, 59, 1504–1512.
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 1504-1512
    • Rodriguez-Mateos, A.1    Cifuentes-Gomez, T.2    Gonzalez-Salvador, I.3    Ottaviani, J.I.4
  • 20
    • 78651249150 scopus 로고    scopus 로고
    • The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo
    • Ottaviani, J. I., Momma, T. Y., Heiss, C., Kwik-Uribe, C. et al., The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo. Free Radic. Biol. Med. 2011, 50, 237–244.
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 237-244
    • Ottaviani, J.I.1    Momma, T.Y.2    Heiss, C.3    Kwik-Uribe, C.4
  • 21
    • 33746851173 scopus 로고    scopus 로고
    • Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function
    • Nicholls, S. J., Lundman, P., Harmer, J. A., Cutri, B. et al., Consumption of saturated fat impairs the anti-inflammatory properties of high-density lipoproteins and endothelial function. J. Am. Coll. Cardiol. 2006, 48, 715–720.
    • (2006) J. Am. Coll. Cardiol. , vol.48 , pp. 715-720
    • Nicholls, S.J.1    Lundman, P.2    Harmer, J.A.3    Cutri, B.4
  • 22
    • 0038620491 scopus 로고    scopus 로고
    • Postprandial recruitment of neutrophils may contribute to endothelial dysfunction
    • van Oostrom, A. J. H. H. M., Sijmonsma, T. P., Verseyden, C., Jansen, E. H. J. M. et al., Postprandial recruitment of neutrophils may contribute to endothelial dysfunction. J. Lipid Res. 2003, 44, 576–583.
    • (2003) J. Lipid Res. , vol.44 , pp. 576-583
    • van Oostrom, A.J.H.H.M.1    Sijmonsma, T.P.2    Verseyden, C.3    Jansen, E.H.J.M.4
  • 23
    • 78149239022 scopus 로고    scopus 로고
    • Oral magnesium supplementation improves vascular function in elderly diabetic patients
    • Barbagallo, M., Dominguez, L. J., Galioto, A., Pineo, A. et al., Oral magnesium supplementation improves vascular function in elderly diabetic patients. Magnes. Res. 2010, 23, 131–137.
    • (2010) Magnes. Res. , vol.23 , pp. 131-137
    • Barbagallo, M.1    Dominguez, L.J.2    Galioto, A.3    Pineo, A.4
  • 24
    • 0034619507 scopus 로고    scopus 로고
    • Oral magnesium therapy improves endothelial function in patients with coronary artery disease
    • Shechter, M., Sharir, M., Paul, M. J., James, L. et al., Oral magnesium therapy improves endothelial function in patients with coronary artery disease. Circulation 2000, 102, 2353–2358.
    • (2000) Circulation , vol.102 , pp. 2353-2358
    • Shechter, M.1    Sharir, M.2    Paul, M.J.3    James, L.4
  • 25
    • 84909590098 scopus 로고    scopus 로고
    • Effects of magnesium supplements on blood pressure, endothelial function and metabolic parameters in healthy young men with a family history of metabolic syndrome
    • Cosaro, E., Bonafini, S., Montagnana, M., Danese, E. et al., Effects of magnesium supplements on blood pressure, endothelial function and metabolic parameters in healthy young men with a family history of metabolic syndrome. Nutr. Metab. Cardiovasc. Dis. 2014, 24, 1213–1220.
    • (2014) Nutr. Metab. Cardiovasc. Dis. , vol.24 , pp. 1213-1220
    • Cosaro, E.1    Bonafini, S.2    Montagnana, M.3    Danese, E.4
  • 26
    • 84875670083 scopus 로고    scopus 로고
    • Effect of magnesium supplementation on carotid intima-media thickness and flow-mediated dilatation among hemodialysis patients: a double-blind, randomized, placebo-controlled trial
    • Mortazavi, M., Moeinzadeh, F., Saadatnia, M., Shahidi, S. et al., Effect of magnesium supplementation on carotid intima-media thickness and flow-mediated dilatation among hemodialysis patients: a double-blind, randomized, placebo-controlled trial. Eur. Neurol. 2013, 69, 309–316.
    • (2013) Eur. Neurol. , vol.69 , pp. 309-316
    • Mortazavi, M.1    Moeinzadeh, F.2    Saadatnia, M.3    Shahidi, S.4
  • 27
    • 33847216227 scopus 로고    scopus 로고
    • Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week
    • Heiss, C., Finis, D., Kleinbongard, P., Hoffmann, A. et al., Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week. J. Cardiovasc. Pharmacol. 2007, 49, 74–80.
    • (2007) J. Cardiovasc. Pharmacol. , vol.49 , pp. 74-80
    • Heiss, C.1    Finis, D.2    Kleinbongard, P.3    Hoffmann, A.4
  • 28
    • 77955060311 scopus 로고    scopus 로고
    • Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease
    • Heiss, C., Jahn, S., Taylor, M., Real, W. M. et al., Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease. J. Am. Coll. Cardiol. 2010, 56, 218–224.
    • (2010) J. Am. Coll. Cardiol. , vol.56 , pp. 218-224
    • Heiss, C.1    Jahn, S.2    Taylor, M.3    Real, W.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.