Soluble Epoxide Hydrolase Inhibitor Suppresses the Expression of Triggering Receptor Expressed on Myeloid Cells-1 by Inhibiting NF-kB Activation in Murine Macrophage

Inflammation

Volumn 40, Issue 1, 2017, Pages 13-20

  Dong, Liang ^a,b   Zhou, Yong ^a   Zhu, Zhao Qiong ^b   Liu, Tian ^a   Duan, Jia Xi ^a   Zhang, Jun ^c   Li, Ping ^a   Hammcok, Bruce D ^d   Guan, Cha Xiang ^a  

^a The First People s Hospital of Changde City)   (China)

^b ZUNYI MEDICAL UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

epoxyeicosatrienoic acids; inflammation; macrophage; soluble epoxide hydrolase inhibitor; triggering receptor expressed on myeloid cells 1

Indexed keywords

1 TRIFLUOROMETHOXYPHENYL 3 (1 PROPIONYLPIPERIDIN 4 YL)UREA; ANTIINFLAMMATORY AGENT; EPOXIDE HYDROLASE; EPOXYICOSATRIENOIC ACID; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; HYDROLASE INHIBITOR; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; 1-TRIFLUOROMETHOXYPHENYL-3-(1-PROPIONYLPIPERIDINE-4-YL)UREA; CARBANILAMIDE DERIVATIVE; CYTOKINE; I KAPPA B BETA; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; PIPERIDINE DERIVATIVE; TREM1 PROTEIN, MOUSE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME INHIBITION; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PNEUMONIA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; GENE EXPRESSION; MACROPHAGE; METABOLISM; SOLUBILITY;

ANIMALS; CELLS, CULTURED; CYTOKINES; EPOXIDE HYDROLASES; GENE EXPRESSION; I-KAPPA B PROTEINS; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MYELOID CELLS; NF-KAPPA B; PHENYLUREA COMPOUNDS; PIPERIDINES; PNEUMONIA; RECEPTORS, IMMUNOLOGIC; SOLUBILITY;

EID: 84989157868     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-016-0448-6     Document Type: Article

References (31)

1. Yong, Y. K., E. M. Shankar, A. Solomon, T. Spelman, C. K. Fairley, J. Elliott, et al. 2016. Polymorphisms in the CD14 and TLR4 genes independently predict CD4+ T-cell recovery in HIV-infected individuals on antiretroviral therapy. AIDS.
2. Aghagolzadeh, P., M. Bachtler, R. Bijarnia, C. Jackson, E. R. Smith, A. Odermatt, et al. 2016. Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-alpha. Atherosclerosis.
3. Minutti, C. M., B. Garcia-Fojeda, A. Saenz, M. de Las Casas-Engel, R. Guillamat-Prats, A. de Lorenzo, et al. 2016. Surfactant Protein A Prevents IFN-gamma/IFN-gamma Receptor Interaction and Attenuates Classical Activation of Human Alveolar Macrophages. J Immunol.
4. Bouchon, A., J. Dietrich, and M. Colonna. 2000. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. Journal of Immunology 164: 4991–4995.
5. Arts, R.J., L.A. Joosten, J.W. van der Meer, and M.G. Netea. 2013. TREM-1: intracellular signaling pathways and interaction with pattern recognition receptors. Journal of Leukocyte Biology 93: 209–215.
6. Fan, D., X. He, Y. Bian, Q. Guo, K. Zheng, Y. Zhao, et al. 2016. Triptolide modulates TREM-1 signal pathway to inhibit the inflammatory response in rheumatoid arthritis. International Journal of Molecular Sciences 17.
7. Rigo, I., L. McMahon, P. Dhawan, S. Christakos, S. Yim, L.K. Ryan, et al. 2012. Induction of triggering receptor expressed on myeloid cells (TREM-1) in airway epithelial cells by 1,25(OH)(2) vitamin D(3). Innate Immunity 18: 250–257.
8. Willi, M., G.N. Belibasakis, and N. Bostanci. 2014. Expression and regulation of triggering receptor expressed on myeloid cells 1 in periodontal diseases. Clinical and Experimental Immunology 178: 190–200.
9. Jeremie, L., B. Amir, D. Marc, and G. Sebastien. 2015. The triggering receptor expressed on myeloid cells-1: a new player during acute myocardial infarction. Pharmacological Research 100: 261–265.
10. Genua, M., S. Rutella, C. Correale, and S. Danese. 2014. The triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesis. Journal of Translational Medicine 12: 293.
11. Yuan, Z., M. Syed, D. Panchal, M. Joo, C. Bedi, S. Lim, et al. 2016. TREM-1-accentuated lung injury via miR-155 is inhibited by LP17 nanomedicine. American Journal of Physiology - Lung Cellular and Molecular Physiology 310: L426–L438.
12. Zhong, J., W. Huang, Q. Deng, M. Wu, H. Jiang, X. Lin, et al. 2016. Inhibition of TREM-1 and Dectin-1 alleviates the severity of fungal keratitis by modulating innate immune responses. PLoS One 11: e0150114.
13. Sun, G.Y., C.X. Guan, Y. Zhou, Y.P. Liu, S.F. Li, H.F. Zhou, et al. 2011. Vasoactive intestinal peptide re-balances TREM-1/TREM-2 ratio in acute lung injury. Regulatory Peptides 167: 56–64.
14. Zheng, H., C.A. Heiderscheidt, M. Joo, X. Gao, N. Knezevic, D. Mehta, et al. 2010. MYD88-dependent and -independent activation of TREM-1 via specific TLR ligands. European Journal of Immunology 40: 162–171.
15. Huang, H., J. Weng, and M. H. Wang. 2016. EETs/sEH in diabetes and obesity-induced cardiovascular diseases. Prostaglandins Other Lipid Mediat.
16. Pillarisetti, S., and I. Khanna. 2015. A multimodal disease modifying approach to treat neuropathic pain–inhibition of soluble epoxide hydrolase (sEH). Drug Discovery Today 20: 1382–1390.
17. Zhou, Y., G.Y. Sun, T. Liu, J.X. Duan, H.F. Zhou, K.S. Lee, et al. 2016. Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice. Cell and Tissue Research 363: 399–409.
18. Ren, Q., M. Ma, T. Ishima, C. Morisseau, J. Yang, K.M. Wagner, et al. 2016. Gene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stress. Proceedings of the National Academy of Sciences of the United States of America 113: E1944–E1952.
19. Bettaieb, A., S. Chahed, S. Bachaalany, S. Griffey, B.D. Hammock, and F.G. Haj. 2015. Soluble epoxide hydrolase pharmacological inhibition ameliorates experimental acute pancreatitis in mice. Molecular Pharmacology 88: 281–290.
20. Lopez-Vicario, C., J. Alcaraz-Quiles, V. Garcia-Alonso, B. Rius, S.H. Hwang, E. Titos, et al. 2015. Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: role for omega-3 epoxides. Proceedings of the National Academy of Sciences of the United States of America 112: 536–541.
21. Qi, D., J. He, D. Wang, W. Deng, Y. Zhao, Y. Ye, et al. 2014. 17beta-estradiol suppresses lipopolysaccharide-induced acute lung injury through PI3K/Akt/SGK1 mediated up-regulation of epithelial sodium channel (ENaC) in vivo and in vitro. Respiratory Research 15: 159.
22. Park, J. S., M. Y. Park, Y. J. Cho, J. H. Lee, C. G. Yoo, C. T. Lee, et al. 2016. Anti-inflammatory effect of erdosteine in lipopolysaccharide-stimulated RAW 264.7 cells. Inflammation.
23. Peng, L., Y. Zhou, L. Dong, R.Q. Chen, G.Y. Sun, T. Liu, et al. 2016. TGF-beta1 upregulates the expression of triggering receptor expressed on myeloid cells 1 in murine lungs. Science Reports 6: 18946.
24. Tao, F., L. Peng, J. Li, Y. Shao, L. Deng, and H. Yao. 2013. Association of serum myeloid cells of soluble triggering receptor-1 level with myocardial dysfunction in patients with severe sepsis. Mediators of Inflammation 2013: 819246.
25. Bostanci, N., V.O. Ozturk, G. Emingil, and G.N. Belibasakis. 2013. Elevated oral and systemic levels of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in periodontitis. Journal of Dental Research 92: 161–165.
26. Murakami, Y., H. Kohsaka, H. Kitasato, and T. Akahoshi. 2007. Lipopolysaccharide-induced up-regulation of triggering receptor expressed on myeloid cells-1 expression on macrophages is regulated by endogenous prostaglandin E2. Journal of Immunology 178: 1144–1150.
27. Rao, V.H., V. Rai, S. Stoupa, S. Subramanian, and D.K. Agrawal. 2016. Tumor necrosis factor-alpha regulates triggering receptor expressed on myeloid cells-1-dependent matrix metalloproteinases in the carotid plaques of symptomatic patients with carotid stenosis. Atherosclerosis 248: 160–169.
28. Kim, T.H., B. Lee, E. Kwon, S.J. Choi, Y.H. Lee, G.G. Song, et al. 2013. Regulation of TREM-1 expression by 1,25-dihydroxyvitamin D3 in human monocytes/macrophages. Immunology Letters 154: 80–85.
29. Morisseau, C., and B.D. Hammock. 2013. Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health. Annual Review of Pharmacology and Toxicology 53: 37–58.
30. Tsai, H.J., S.H. Hwang, C. Morisseau, J. Yang, P.D. Jones, T. Kasagami, et al. 2010. Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs. European Journal of Pharmaceutical Sciences 40: 222–238.
31. Chen, D., R. Whitcomb, E. MacIntyre, V. Tran, Z.N. Do, J. Sabry, et al. 2012. Pharmacokinetics and pharmacodynamics of AR9281, an inhibitor of soluble epoxide hydrolase, in single- and multiple-dose studies in healthy human subjects. Journal of Clinical Pharmacology 52: 319–328.