Soluble epoxide hydrolase inhibitor 1-trifluoromethoxyphenyl-3- (1-propionylpiperidin-4-yl) urea attenuates bleomycin-induced pulmonary fibrosis in mice

Cell and Tissue Research

Volumn 363, Issue 2, 2016, Pages 399-409

  Zhou, Yong ^a   Sun, Guo Ying ^a   Liu, Tian ^a   Duan, Jia Xi ^a   Zhou, Hui Fang ^a   Lee, Kin Sing ^b   Hammock, Bruce D ^b   Fang, Xiang ^c   Jiang, Jian Xin ^d   Guan, Cha Xiang ^a  

^a Central South University   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Epoxyeicosatrienoic acids; Mouse; Proliferation; Pulmonary fibrosis; Soluble epoxide hydrolase inhibitor

Indexed keywords

1 TRIFLUOROMETHOXYPHENYL 3 (1 PROPIONYLPIPERIDIN 4 YL)UREA; ALPHA SMOOTH MUSCLE ACTIN; BLEOMYCIN; COLLAGEN TYPE 1; EPOXIDE HYDROLASE; EPOXYICOSATRIENOIC ACID; HYDROLASE INHIBITOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROCOLLAGEN; PROCOLLAGEN 1; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; 1-TRIFLUOROMETHOXYPHENYL-3-(1-PROPIONYLPIPERIDINE-4-YL)UREA; CARBANILAMIDE DERIVATIVE; COLLAGEN; ICOSANOID; PIPERIDINE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL DIFFERENTIATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENZYME INHIBITION; FIBROBLAST; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LUNG FIBROSIS; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SURVIVAL RATE; WEIGHT REDUCTION; 3T3 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; C57BL MOUSE; CELL CYCLE S PHASE; CELL DEATH; CELL PROLIFERATION; CHEMICALLY INDUCED; CHEMISTRY; DRUG EFFECTS; LUNG; METABOLISM; PATHOLOGY; PULMONARY FIBROSIS; SOLUBILITY;

ANIMALS; BLEOMYCIN; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN; EICOSANOIDS; EPOXIDE HYDROLASES; FIBROBLASTS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LUNG; MALE; MICE; MICE, INBRED C57BL; NIH 3T3 CELLS; PHENYLUREA COMPOUNDS; PIPERIDINES; PULMONARY FIBROSIS; S PHASE; SOLUBILITY; TRANSFORMING GROWTH FACTOR BETA1; WEIGHT LOSS;

EID: 84956887527     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-015-2262-0     Document Type: Article

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