Lysophosphatidic acid signaling through the lysophosphatidic acid-1 receptor is required for alveolarization

American Journal of Respiratory Cell and Molecular Biology

Volumn 55, Issue 1, 2016, Pages 105-116

  Funke, Manuela ^a,b   Knudsen, Lars ^c   Lagares, David ^b   Ebener, Simone ^a   Probst, Clemens K ^b   Fontaine, Benjamin A ^b   Franklin, Alicia ^b   Kellner, Manuela ^c   Kühnel, Mark ^c   Matthieu, Stephanie ^c   Grothausmann, Roman ^c   Chun, Jerold ^d   Roberts, Jesse D ^e   Ochs, Matthias ^c   Tager, Andrew M ^b  

^a UNIVERSITY OF BERN   (Switzerland)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alveolarization; Elastin; LPA1; Lung development; Matrix metalloproteinase

Indexed keywords

ELASTIN; GELATINASE A; GELATINASE B; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDIC ACID RECEPTOR; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE; MESSENGER RNA; TROPOELASTIN; LYSOPHOSPHOLIPID; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRANCHING MORPHOGENESIS; CELL MIGRATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; ELASTIC FIBER; EMPHYSEMA; EXTRACELLULAR MATRIX; LUNG ALVEOLUS; LUNG DEVELOPMENT; LUNG FIBROBLAST; LUNG HOMOGENATE; LUNG PARENCHYMA; MOUSE; MYOFIBROBLAST; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURFACE AREA; TOTAL LUNG CAPACITY; ANIMAL; C57BL MOUSE; CELL COUNT; CELL MOTION; CELL SIZE; ELASTICITY; FIBROBLAST; KNOCKOUT MOUSE; METABOLISM; MORPHOGENESIS;

ANIMALS; CELL COUNT; CELL MOVEMENT; CELL SIZE; ELASTICITY; ELASTIN; EXTRACELLULAR MATRIX; FIBROBLASTS; LYSOPHOSPHOLIPIDS; MATRIX METALLOPROTEINASES; MICE, INBRED C57BL; MICE, KNOCKOUT; MORPHOGENESIS; PULMONARY ALVEOLI; RECEPTORS, LYSOPHOSPHATIDIC ACID; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASES; TROPOELASTIN;

EID: 84988942707     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2015-0152OC     Document Type: Article

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