Endocytosis of cytotoxic granules is essential for multiple killing of target cells by T lymphocytes

Journal of Immunology

Volumn 197, Issue 6, 2016, Pages 2473-2484

  Chang, Hsin Fang ^a   Bzeih, Hawraa ^a   Schirra, Claudia ^a   Chitirala, Praneeth ^a   Halimani, Mahantappa ^a,c   Cordat, Emmanuelle ^b   Krause, Elmar ^a   Rettig, Jens ^a   Pattu, Varsha ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF ALBERTA   (Canada)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLATHRIN; DYNAMIN; SYNAPTOBREVIN 2; GRANZYME; SYNAPTOBREVIN;

ACIDIFICATION; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CELL GRANULE; CELL KILLING; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; ELECTRON MICROSCOPY; ENDOCYTOSIS; ENDOSOME; FLUORESCENCE MICROSCOPY; IMAGE ANALYSIS; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PLASMID; POLARIZATION; PRIORITY JOURNAL; SPLEEN CELL; SYNAPSE; TIME LAPSE IMAGING; ANIMAL; EXOCYTOSIS; IMMUNOLOGICAL SYNAPSE; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; CLATHRIN; CYTOPLASMIC GRANULES; DYNAMINS; ENDOCYTOSIS; ENDOSOMES; EXOCYTOSIS; GRANZYMES; IMMUNOLOGICAL SYNAPSES; MICE; R-SNARE PROTEINS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84988931707     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1600828     Document Type: Article

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