-
1
-
-
0036303033
-
Mechanisms and functions of Eph and ephrin signalling
-
Kullander K, Klein R (2002) Mechanisms and functions of Eph and ephrin signalling. Nat Rev Mol Cell Biol 3:475-486
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 475-486
-
-
Kullander, K.1
Klein, R.2
-
2
-
-
0041669478
-
'Eph'ective signaling: Forward, reverse and crosstalk
-
Murai KK, Pasquale EB (2003) 'Eph'ective signaling: forward, reverse and crosstalk. J Cell Sci 116:2823-2832
-
(2003)
J Cell Sci
, vol.116
, pp. 2823-2832
-
-
Murai, K.K.1
Pasquale, E.B.2
-
3
-
-
0028129144
-
Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors
-
Beckmann MP, Cerretti DP, Baum P et al (1994) Molecular characterization of a family of ligands for eph-related tyrosine kinase receptors. EMBO J 13:3757-3762
-
(1994)
EMBO J
, vol.13
, pp. 3757-3762
-
-
Beckmann, M.P.1
Cerretti, D.P.2
Baum, P.3
-
4
-
-
0028110068
-
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity
-
Davis S, Gale NW, Aldrich TH et al (1994) Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity. Science 266:816-819
-
(1994)
Science
, vol.266
, pp. 816-819
-
-
Davis, S.1
Gale, N.W.2
Aldrich, T.H.3
-
5
-
-
23744465239
-
Regulation of EphA4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function
-
Egea J, Nissen UV, Dufour A et al (2005) Regulation of EphA4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron 47:515-528
-
(2005)
Neuron
, vol.47
, pp. 515-528
-
-
Egea, J.1
Nissen, U.V.2
Dufour, A.3
-
6
-
-
25144472138
-
Eph receptor signalling: Dimerisation just isn't enough
-
Vearing CJ, Lackmann M (2005) Eph receptor signalling: dimerisation just isn't enough. Growth Factors 23:67-76
-
(2005)
Growth Factors
, vol.23
, pp. 67-76
-
-
Vearing, C.J.1
Lackmann, M.2
-
7
-
-
11144354644
-
Repelling class discrimination: Ephrin- A5 binds to and activates EphB2 receptor signaling
-
Himanen JP, Chumley MJ, Lackmann M et al (2004) Repelling class discrimination: ephrin- A5 binds to and activates EphB2 receptor signaling. Nat Neurosci 7:501-509
-
(2004)
Nat Neurosci
, vol.7
, pp. 501-509
-
-
Himanen, J.P.1
Chumley, M.J.2
Lackmann, M.3
-
8
-
-
0030728938
-
Ephrins and their receptors: A repulsive topic
-
Gale NW, Yancopoulos GD (1997) Ephrins and their receptors: a repulsive topic? Cell Tissue Res 290:227-241
-
(1997)
Cell Tissue Res
, vol.290
, pp. 227-241
-
-
Gale, N.W.1
Yancopoulos, G.D.2
-
9
-
-
0031922119
-
The ephrins and Eph receptors in neural development
-
Flanagan JG, Vanderhaeghen P (1998) The ephrins and Eph receptors in neural development. Annu Rev Neurosci 21:309-345
-
(1998)
Annu Rev Neurosci
, vol.21
, pp. 309-345
-
-
Flanagan, J.G.1
Vanderhaeghen, P.2
-
10
-
-
1542358915
-
Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers
-
Hafner C, Schmitz G, Meyer S et al (2004) Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers. Clin Chem 50:490-499
-
(2004)
Clin Chem
, vol.50
, pp. 490-499
-
-
Hafner, C.1
Schmitz, G.2
Meyer, S.3
-
11
-
-
41149084179
-
Eph-ephrin bidirectional signaling in physiology and disease
-
Pasquale EB (2008) Eph-ephrin bidirectional signaling in physiology and disease. Cell 133:38-52
-
(2008)
Cell
, vol.133
, pp. 38-52
-
-
Pasquale, E.B.1
-
12
-
-
0030807905
-
The Eph family: A multitude of receptors that mediate cell recognition signals
-
Zisch AH, Pasquale EB (1997) The Eph family: a multitude of receptors that mediate cell recognition signals. Cell Tissue Res 290:217-226
-
(1997)
Cell Tissue Res
, vol.290
, pp. 217-226
-
-
Zisch, A.H.1
Pasquale, E.B.2
-
13
-
-
4444326581
-
Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer
-
Huusko P, Ponciano-Jackson D, Wolf M et al (2004) Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer. Nat Genet 36:979-983
-
(2004)
Nat Genet
, vol.36
, pp. 979-983
-
-
Huusko, P.1
Ponciano-Jackson, D.2
Wolf, M.3
-
14
-
-
33745253118
-
A common nonsense mutation in EphB2 is associated with prostate cancer risk in African American men with a positive family history
-
Kittles RA, Baffoe-Bonnie AB, Moses TY et al (2006) A common nonsense mutation in EphB2 is associated with prostate cancer risk in African American men with a positive family history. J Med Genet 43:507-511
-
(2006)
J Med Genet
, vol.43
, pp. 507-511
-
-
Kittles, R.A.1
Baffoe-Bonnie, A.B.2
Moses, T.Y.3
-
15
-
-
28544450494
-
Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors
-
Alazzouzi H, Davalos V, Kokko A et al (2005) Mechanisms of inactivation of the receptor tyrosine kinase EPHB2 in colorectal tumors. Cancer Res 65:10170-10173
-
(2005)
Cancer Res
, vol.65
, pp. 10170-10173
-
-
Alazzouzi, H.1
Davalos, V.2
Kokko, A.3
-
16
-
-
33644866330
-
Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours
-
Guo DL, Zhang J, Yuen ST et al (2006) Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumours. Carcinogenesis 27:454-464
-
(2006)
Carcinogenesis
, vol.27
, pp. 454-464
-
-
Guo, D.L.1
Zhang, J.2
Yuen, S.T.3
-
17
-
-
33746929036
-
Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin
-
Guo H, Miao H, Gerber L, Singh J, Denning MF, Gilliam AC, Wang B (2006) Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin. Cancer Res 66(14):7050-7058
-
(2006)
Cancer Res
, vol.66
, Issue.14
, pp. 7050-7058
-
-
Guo, H.1
Miao, H.2
Gerber, L.3
Singh, J.4
Denning, M.F.5
Gilliam, A.C.6
Wang, B.7
-
18
-
-
0034790653
-
Downregulation of the Ras-mitogen- activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin- induced neurite retraction
-
Elowe S, Holland SJ, Kulkarni S, Pawson T (2001) Downregulation of the Ras-mitogen- activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin- induced neurite retraction. Mol Cell Biol 21(21):7429-7441
-
(2001)
Mol Cell Biol
, vol.21
, Issue.21
, pp. 7429-7441
-
-
Elowe, S.1
Holland, S.J.2
Kulkarni, S.3
Pawson, T.4
-
19
-
-
0033598742
-
An Eph receptor regulates integrin activity through R-Ras
-
Zou JX, Wang B, Kalo MS, Zisch AH, Pasquale EB, Ruoslahti E (1999) An Eph receptor regulates integrin activity through R-Ras. Proc Natl Acad Sci USA 96:13813-13818
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13813-13818
-
-
Zou, J.X.1
Wang, B.2
Kalo, M.S.3
Zisch, A.H.4
Pasquale, E.B.5
Ruoslahti, E.6
-
20
-
-
25144492370
-
EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion
-
Nakada M, Niska JA, Tran NL, McDonough WS, Berens ME (2005) EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion. Am J Pathol 167:565-576
-
(2005)
Am J Pathol
, vol.167
, pp. 565-576
-
-
Nakada, M.1
Niska, J.A.2
Tran, N.L.3
McDonough, W.S.4
Berens, M.E.5
-
21
-
-
34247254812
-
The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome
-
Kumar SR, Masood R, Spannuth WA et al (2007) The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome. Br J Cancer 96:1083-1091
-
(2007)
Br J Cancer
, vol.96
, pp. 1083-1091
-
-
Kumar, S.R.1
Masood, R.2
Spannuth, W.A.3
-
22
-
-
65949098678
-
Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression
-
Kumar SR, Scehnet JS, Ley EJ, Singh J et al (2009) Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression. Cancer Res 69(9):3736-3745
-
(2009)
Cancer Res
, vol.69
, Issue.9
, pp. 3736-3745
-
-
Kumar, S.R.1
Scehnet, J.S.2
Ley, E.J.3
Singh, J.4
-
23
-
-
33746646032
-
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway
-
Noren NK, Foos G, Hauser CA, Pasquale EB (2006) The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway. Nat Cell Biol 8:815-825
-
(2006)
Nat Cell Biol
, vol.8
, pp. 815-825
-
-
Noren, N.K.1
Foos, G.2
Hauser, C.A.3
Pasquale, E.B.4
-
24
-
-
0025251177
-
CDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases
-
Lindberg RA, Hunter T (1990) cDNA cloning and characterization of eck, an epithelial cell receptor protein-tyrosine kinase in the eph/elk family of protein kinases. Mol Cell Biol 10:6316-6324
-
(1990)
Mol Cell Biol
, vol.10
, pp. 6316-6324
-
-
Lindberg, R.A.1
Hunter, T.2
-
25
-
-
0028237580
-
The expression of the receptor-protein tyrosine kinase gene, eck, is highly restricted during early mouse development
-
Ruiz JC, Robertson EJ (1994) The expression of the receptor-protein tyrosine kinase gene, eck, is highly restricted during early mouse development. Mech Dev 46:87-100
-
(1994)
Mech Dev
, vol.46
, pp. 87-100
-
-
Ruiz, J.C.1
Robertson, E.J.2
-
26
-
-
0029961757
-
Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion
-
Chen J, Nachabah A, Scherer C et al (1996) Germ-line inactivation of the murine Eck receptor tyrosine kinase by gene trap retroviral insertion. Oncogene 12:979-988
-
(1996)
Oncogene
, vol.12
, pp. 979-988
-
-
Chen, J.1
Nachabah, A.2
Scherer, C.3
-
27
-
-
18844392603
-
EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics
-
Ireton RC, Chen J (2005) EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics. Curr Cancer Drug Targets 5(3):149-157
-
(2005)
Curr Cancer Drug Targets
, vol.5
, Issue.3
, pp. 149-157
-
-
Ireton, R.C.1
Chen, J.2
-
28
-
-
57749121465
-
The EphA2 receptor and ephrinA1 ligand in solid tumors: Function and therapeutic targeting
-
Wykosky J, Debinski W (2008) The EphA2 receptor and ephrinA1 ligand in solid tumors: function and therapeutic targeting. Mol Cancer Res 6(12):1795-1806
-
(2008)
Mol Cancer Res
, vol.6
, Issue.12
, pp. 1795-1806
-
-
Wykosky, J.1
Debinski, W.2
-
29
-
-
10744222309
-
High-level expression of EphA2 receptor tyrosine kinase in prostatic intraepithelial neoplasia
-
Zeng G, Hu Z, Kinch MS et al (2003) High-level expression of EphA2 receptor tyrosine kinase in prostatic intraepithelial neoplasia. Am J Pathol 163:2271-2276
-
(2003)
Am J Pathol
, vol.163
, pp. 2271-2276
-
-
Zeng, G.1
Hu, Z.2
Kinch, M.S.3
-
30
-
-
4143123295
-
EphA2 expression is associated with aggressive features in ovarian carcinoma
-
Thaker PH, Deavers M, Celestino J et al (2004) EphA2 expression is associated with aggressive features in ovarian carcinoma. Clin Cancer Res 10:5145-5150
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5145-5150
-
-
Thaker, P.H.1
Deavers, M.2
Celestino, J.3
-
31
-
-
33846651832
-
Patterns of EphA2 protein expression in primary and metastatic pancreatic carcinoma and correlation with genetic status
-
Mudali SV, Fu B, Lakkur SS, Luo M, Embuscado EE, Iacobuzio-Donahue CA (2006) Patterns of EphA2 protein expression in primary and metastatic pancreatic carcinoma and correlation with genetic status. Clin Exp Metastasis 23:357-365
-
(2006)
Clin Exp Metastasis
, vol.23
, pp. 357-365
-
-
Mudali, S.V.1
Fu, B.2
Lakkur, S.S.3
Luo, M.4
Embuscado, E.E.5
Iacobuzio-Donahue, C.A.6
-
32
-
-
27644466229
-
EphA2 as a novel molecular marker and target in glioblastoma multiforme
-
Wykosky J, Gibo DM, Stanton C, Debinski W (2005) EphA2 as a novel molecular marker and target in glioblastoma multiforme. Mol Cancer Res 3:541-551
-
(2005)
Mol Cancer Res
, vol.3
, pp. 541-551
-
-
Wykosky, J.1
Gibo, D.M.2
Stanton, C.3
Debinski, W.4
-
33
-
-
0032708010
-
Overexpression of the EphA2 tyrosine kinase in prostate cancer
-
Walker-Daniels J, Coffman K, Azimi M et al (1999) Overexpression of the EphA2 tyrosine kinase in prostate cancer. Prostate 41:275-280
-
(1999)
Prostate
, vol.41
, pp. 275-280
-
-
Walker-Daniels, J.1
Coffman, K.2
Azimi, M.3
-
34
-
-
2442419137
-
Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application
-
Fox BP, Kandpal RP (2004) Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application. Biochem Biophys Res Commun 318:882-892
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 882-892
-
-
Fox, B.P.1
Kandpal, R.P.2
-
35
-
-
0037314612
-
Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival
-
Kinch MS, Moore MB, Harpole DH (2003) Predictive value of the EphA2 receptor tyrosine kinase in lung cancer recurrence and survival. Clin Cancer Res 9:613-618
-
(2003)
Clin Cancer Res
, vol.9
, pp. 613-618
-
-
Kinch, M.S.1
Moore, M.B.2
Harpole, D.H.3
-
36
-
-
0037455813
-
EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma
-
Miyazaki T, Kato H, Fukuchi M, Nakajima M, Kuwano H (2003) EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma. Int J Cancer 103: 657-663
-
(2003)
Int J Cancer
, vol.103
, pp. 657-663
-
-
Miyazaki, T.1
Kato, H.2
Fukuchi, M.3
Nakajima, M.4
Kuwano, H.5
-
37
-
-
27144524979
-
The clinical significance of EphA2 and Ephrin A-1 in epithelial ovarian carcinomas
-
Han L, Dong Z, Qiao Y (2005) The clinical significance of EphA2 and Ephrin A-1 in epithelial ovarian carcinomas. Gynecol Oncol 99:278-286
-
(2005)
Gynecol Oncol
, vol.99
, pp. 278-286
-
-
Han, L.1
Dong, Z.2
Qiao, Y.3
-
38
-
-
0035870251
-
Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: Role of epithelial cell kinase (Eck/EphA2)
-
Hess AR, Seftor EA, Gardner LM et al (2001) Molecular regulation of tumor cell vasculogenic mimicry by tyrosine phosphorylation: role of epithelial cell kinase (Eck/EphA2). Cancer Res 61:3250-3255
-
(2001)
Cancer Res
, vol.61
, pp. 3250-3255
-
-
Hess, A.R.1
Seftor, E.A.2
Gardner, L.M.3
-
39
-
-
38749092525
-
Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients
-
Wang LF, Fokas E, Bieker M et al (2008) Increased expression of EphA2 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients. Oncol Rep 19:151-156
-
(2008)
Oncol Rep
, vol.19
, pp. 151-156
-
-
Wang, L.F.1
Fokas, E.2
Bieker, M.3
-
40
-
-
0035266163
-
EphA2 overexpression causes tumorigenesis of mammary epithelial cells
-
Zelinski DP, Zantek ND, Stewart JC, Irizarry AR, Kinch MS (2001) EphA2 overexpression causes tumorigenesis of mammary epithelial cells. Cancer Res 61:2301-2316
-
(2001)
Cancer Res
, vol.61
, pp. 2301-2316
-
-
Zelinski, D.P.1
Zantek, N.D.2
Stewart, J.C.3
Irizarry, A.R.4
Kinch, M.S.5
-
41
-
-
28344446374
-
A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis
-
Fang WB, Brantley-Sieders DM, Parker MA, Reith AD, Chen J (2005) A kinase-dependent role for EphA2 receptor in promoting tumor growth and metastasis. Oncogene 24:7859
-
(2005)
Oncogene
, vol.24
, pp. 7859
-
-
Fang, W.B.1
Brantley-Sieders, D.M.2
Parker, M.A.3
Reith, A.D.4
Chen, J.5
-
42
-
-
33947225176
-
Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: Rationale for patient selection
-
Huang F, Reeves K, Han X (2007) Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection. Cancer Res 67: 2226-2238
-
(2007)
Cancer Res
, vol.67
, pp. 2226-2238
-
-
Huang, F.1
Reeves, K.2
Han, X.3
-
43
-
-
77955252631
-
Structure-activity relationship analysis of peptides targeting the EphA2 receptor
-
Mitra S, Duggineni S, Koolpe M, Zhu X, Huang Z, Pasquale EB (2010) Structure-activity relationship analysis of peptides targeting the EphA2 receptor. Biochemistry 49(31):6687-6695
-
(2010)
Biochemistry
, vol.49
, Issue.31
, pp. 6687-6695
-
-
Mitra, S.1
Duggineni, S.2
Koolpe, M.3
Zhu, X.4
Huang, Z.5
Pasquale, E.B.6
-
44
-
-
0037093097
-
Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior
-
Carles-Kinch K, Kilpatrick KE, Stewart JC, Kinch MS (2002) Antibody targeting of the EphA2 tyrosine kinase inhibits malignant cell behavior. Cancer Res 62(10):2840-2847
-
(2002)
Cancer Res
, vol.62
, Issue.10
, pp. 2840-2847
-
-
Carles-Kinch, K.1
Kilpatrick, K.E.2
Stewart, J.C.3
Kinch, M.S.4
-
45
-
-
75149129568
-
Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy
-
Zhuang G, Brantley-Sieders DM, Vaught D, Yu J, Xie L, Wells S et al (2010) Elevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy. Cancer Res 70(1):299-308
-
(2010)
Cancer Res
, vol.70
, Issue.1
, pp. 299-308
-
-
Zhuang, G.1
Brantley-Sieders, D.M.2
Vaught, D.3
Yu, J.4
Xie, L.5
Wells, S.6
-
46
-
-
33646434790
-
Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth
-
Kiewlich D, Zhang J, Gross C et al (2006) Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growth. Neoplasia 8:18-30
-
(2006)
Neoplasia
, vol.8
, pp. 18-30
-
-
Kiewlich, D.1
Zhang, J.2
Gross, C.3
-
47
-
-
34248545438
-
Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct
-
Hammond SA, Lutterbuese R, Roff S et al (2007) Selective targeting and potent control of tumor growth using an EphA2/CD3-Bispecific single-chain antibody construct. Cancer Res 67(8):3927-35
-
(2007)
Cancer Res
, vol.67
, Issue.8
, pp. 3927-3935
-
-
Hammond, S.A.1
Lutterbuese, R.2
Roff, S.3
-
48
-
-
34047268925
-
Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation
-
Zhuang G, Hunter S, Hwang Y, Chen J (2007) Regulation of EphA2 receptor endocytosis by SHIP2 lipid phosphatase via phosphatidylinositol 3-Kinase-dependent Rac1 activation. J Biol Chem 282(4):2683-2694
-
(2007)
J Biol Chem
, vol.282
, Issue.4
, pp. 2683-2694
-
-
Zhuang, G.1
Hunter, S.2
Hwang, Y.3
Chen, J.4
-
49
-
-
56449085913
-
A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo
-
Jackson D, Gooya J, Mao S, Kinneer K, Xu L, Camara M et al (2008) A human antibody-drug conjugate targeting EphA2 inhibits tumor growth in vivo. Cancer Res 68(22):9367-9374
-
(2008)
Cancer Res
, vol.68
, Issue.22
, pp. 9367-9374
-
-
Jackson, D.1
Gooya, J.2
Mao, S.3
Kinneer, K.4
Xu, L.5
Camara, M.6
-
50
-
-
57649123443
-
Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor
-
Wykosky J, Palma E, Gibo DM, Ringler S, Turner CP, Debinski W (2008) Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor. Oncogene 27(58):7260-75273
-
(2008)
Oncogene
, vol.27
, Issue.58
, pp. 7260-75273
-
-
Wykosky, J.1
Palma, E.2
Gibo, D.M.3
Ringler, S.4
Turner, C.P.5
Debinski, W.6
-
51
-
-
69949135318
-
EphA2 immu- noconjugate as molecularly targeted chemotherapy for ovarian carcinoma
-
Lee JW, Han HD, Shahzad MM, Kim SW, Mangala LS, Nick AM et al (2009) EphA2 immu- noconjugate as molecularly targeted chemotherapy for ovarian carcinoma. J Natl Cancer Inst 101 (17): 1193-1205
-
(2009)
J Natl Cancer Inst
, vol.101
, Issue.17
, pp. 1193-1205
-
-
Lee, J.W.1
Han, H.D.2
Shahzad, M.M.3
Kim, S.W.4
Mangala, L.S.5
Nick, A.M.6
-
52
-
-
77951757063
-
EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma
-
Lee JW, Stone RL, Lee SJ, Nam EJ, Roh JW, Nick AM et al (2010) EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma. Clin Cancer Res 16(9):2562-2570
-
(2010)
Clin Cancer Res
, vol.16
, Issue.9
, pp. 2562-2570
-
-
Lee, J.W.1
Stone, R.L.2
Lee, S.J.3
Nam, E.J.4
Roh, J.W.5
Nick, A.M.6
-
53
-
-
10744228315
-
Differential EphA2 epitope display on normal versus malignant cells
-
Coffman KT, Hu M, Carles-Kinch K et al (2003) Differential EphA2 epitope display on normal versus malignant cells. Cancer Res 63:7907-7912
-
(2003)
Cancer Res
, vol.63
, pp. 7907-7912
-
-
Coffman, K.T.1
Hu, M.2
Carles-Kinch, K.3
-
54
-
-
17644391684
-
Antibody humanization by framework shuffling
-
Dall'Acqua WF, Damschroder MM, Zhang J et al (2005) Antibody humanization by framework shuffling. Methods 36(1):43-60
-
(2005)
Methods
, vol.36
, Issue.1
, pp. 43-60
-
-
Dall'Acqua, W.F.1
Damschroder, M.M.2
Zhang, J.3
-
55
-
-
10744222473
-
Development of potent monoclonal antibody auristatin conjugates for cancer therapy
-
Doronina SO, Toki BE, Torgov MY, Mendelsohn BA, Cerveny CG, Chace DF et al (2003) Development of potent monoclonal antibody auristatin conjugates for cancer therapy. Nat Biotechnol 21(7):778-84
-
(2003)
Nat Biotechnol
, vol.21
, Issue.7
, pp. 778-784
-
-
Doronina, S.O.1
Toki, B.E.2
Torgov, M.Y.3
Mendelsohn, B.A.4
Cerveny, C.G.5
Chace, D.F.6
-
56
-
-
0032859305
-
Toxicity of dolastatin 10 in mice, rats and dogs and its clinical relevance
-
Mirsalis JC, Schindler-Horvat J, Hill JR, Tomaszewski JE, Donohue SJ, Tyson CA (1999) Toxicity of dolastatin 10 in mice, rats and dogs and its clinical relevance. Cancer Chemother Pharmacol 44(5):395-402
-
(1999)
Cancer Chemother Pharmacol
, vol.44
, Issue.5
, pp. 395-402
-
-
Mirsalis, J.C.1
Schindler-Horvat, J.2
Hill, J.R.3
Tomaszewski, J.E.4
Donohue, S.J.5
Tyson, C.A.6
-
57
-
-
31544441685
-
Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: Effects of linker technology on efficacy and toxicity
-
Doronina SO, Mendelsohn BA, Bovee TD, Cerveny CG, Alley SC, Meyer DL et al (2006) Enhanced activity of monomethylauristatin F through monoclonal antibody delivery: effects of linker technology on efficacy and toxicity. Bioconjug Chem 17(1):114-124
-
(2006)
Bioconjug Chem
, vol.17
, Issue.1
, pp. 114-124
-
-
Doronina, S.O.1
Mendelsohn, B.A.2
Bovee, T.D.3
Cerveny, C.G.4
Alley, S.C.5
Meyer, D.L.6
-
59
-
-
77952255867
-
Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy
-
Patwardhan G, Gupta V, Huang J, Gu X, Liu YY et al (2010) Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy. Biochem Pharmacol 80(1):72-79
-
(2010)
Biochem Pharmacol
, vol.80
, Issue.1
, pp. 72-79
-
-
Patwardhan, G.1
Gupta, V.2
Huang, J.3
Gu, X.4
Liu, Y.Y.5
|