Carboxyspermidine decarboxylase of the prominent intestinal microbiota species Bacteroides thetaiotaomicron is required for spermidine biosynthesis and contributes to normal growth

Amino Acids

Volumn 48, Issue 10, 2016, Pages 2443-2451

  Sakanaka, Mikiyasu ^a   Sugiyama, Yuta ^a   Kitakata, Aya ^a   Katayama, Takane ^a,b   Kurihara, Shin ^a  

^a ISHIKAWA PREFECTURAL UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Bacteroides; Carboxyspermidine; Carboxyspermidine decarboxylase; Gastrointestinal microbiota; Polyamine; Spermidine

Indexed keywords

CARBOXYLYASE; CARBOXYSPERMIDINE DECARBOXYLASE; SPERMIDINE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN;

ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM IDENTIFICATION; BACTEROIDES THETAIOTAOMICRON; BIOACCUMULATION; BIOSYNTHESIS; CASDC GENE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MODIFICATION; GENE; GENE DELETION; GENETIC CODE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLASMID; PRIORITY JOURNAL; GENETICS; INTESTINE FLORA; METABOLISM;

BACTERIAL PROTEINS; BACTEROIDES THETAIOTAOMICRON; CARBOXY-LYASES; GASTROINTESTINAL MICROBIOME; SPERMIDINE;

EID: 84988893005     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-016-2233-0     Document Type: Article

References (24)

1. 12 analogs and compete in the gut. Cell Host Microbe 15:47–57. doi:10.1016/j.chom.2013.12.007
2. Deng X, Lee J, Michael AJ, Tomchick DR, Goldsmith EJ, Phillips MA (2010) Evolution of substrate specificity within a diverse family of β/α-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for l-arginine and carboxynorspermidine. J Biol Chem 285:25708–25719. doi:10.1074/jbc.M110.121137
3. Driessen AJ, Smid EJ, Konings WN (1988) Transport of diamines by Enterococcus faecalis is mediated by an agmatine-putrescine antiporter. J Bacteriol 170:4522–4527
4. Eisenberg T et al (2009) Induction of autophagy by spermidine promotes longevity. Nat Cell Biol 11:1305–1314. doi:10.1038/ncb1975
5. Furuchi T, Kashiwagi K, Kobayashi H, Igarashi K (1991) Characteristics of the gene for a spermidine and putrescine transport system that maps at 15 min on the Escherichia coli chromosome. J Biol Chem 266:20928–20933
6. Goodman AL et al (2009) Identifying genetic determinants needed to establish a human gut symbiont in its habitat. Cell Host Microbe 6:279–289. doi:10.1016/j.chom.2009.08.003
7. Hamana K, Itoh T, Benno Y, Hayashi H (2008) Polyamine distribution profiles of new members of the phylum Bacteroidetes. J Gen Appl Microbiol 54:229–236. doi:10.2323/jgam.54.229
8. Hanfrey CC et al (2011) Alternative spermidine biosynthetic route is critical for growth of Campylobacter jejuni and is the dominant polyamine pathway in human gut microbiota. J Biol Chem 286:43301–43312. doi:10.1074/jbc.M111.307835
9. Herrero M, de Lorenzo V, Timmis KN (1990) Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteria. J Bacteriol 172:6557–6567
10. Hosoya R, Hamana K (2004) Distribution of two triamines, spermidine and homospermidine, and an aromatic amine, 2-phenylethylamine, within the phylum Bacteroidetes. J Gen Appl Microbiol 50:255–260. doi:10.2323/jgam.50.255
11. Kibe R et al (2014) Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice. Sci Rep 4:4548. doi:10.1038/srep04548
12. Koropatkin NM, Martens EC, Gordon JI, Smith TJ (2008) Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure 16:1105–1115. doi:10.1016/j.str.2008.03.017
13. Lee J, Sperandio V, Frantz DE, Longgood J, Camilli A, Phillips MA, Michael AJ (2009) An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae. J Biol Chem 284:9899–9907. doi:10.1074/jbc.M900110200
14. Lee SM, Donaldson GP, Mikulski Z, Boyajian S, Ley K, Mazmanian SK (2013) Bacterial colonization factors control specificity and stability of the gut microbiota. Nature 501:426–429. doi:10.1038/nature12447
15. Matsumoto M, Kurihara S, Kibe R, Ashida H, Benno Y (2011) Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine production. PLoS ONE 6:e23652. doi:10.1371/journal.pone.0023652
16. Matsumoto M et al (2012) Impact of intestinal microbiota on intestinal luminal metabolome. Sci Rep 2:233. doi:10.1038/srep00233
17. Michael AJ (2015) Biosynthesis of polyamines in eukaryotes, archaea, and bacteria. In: Kusano T, Suzuki H (eds) Polyamines: a universal molecular nexus for growth, survival, and specialized metabolism. Springer, Tokyo, p 3–14. doi:10.1007/978-4-431-55212-3_1
18. Miller-Fleming L, Olin-Sandoval V, Campbell K, Ralser M (2015) Remaining mysteries of molecular biology: the role of polyamines in the cell. J Mol Biol 427:3389–3406. doi:10.1016/j.jmb.2015.06.020
19. Noack J, Kleessen B, Proll J, Dongowski G, Blaut M (1998) Dietary guar gum and pectin stimulate intestinal microbial polyamine synthesis in rats. J Nutr 128:1385–1391
20. Noack J, Dongowski G, Hartmann L, Blaut M (2000) The human gut bacteria Bacteroides thetaiotaomicron and Fusobacterium varium produce putrescine and spermidine in cecum of pectin-fed gnotobiotic rats. J Nutr 130:1225–1231
21. Qin J et al (2010) A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464:59–65. doi:10.1038/nature08821
22. Soda K, Dobashi Y, Kano Y, Tsujinaka S, Konishi F (2009) Polyamine-rich food decreases age-associated pathology and mortality in aged mice. Exp Gerontol 44:727–732. doi:10.1016/j.exger.2009.08.013
23. Tabor CW, Tabor H (1985) Polyamines in microorganisms. Microbiol Rev 49:81–99
24. Uda K, Tsujikawa T, Fujiyama Y, Bamba T (2003) Rapid absorption of luminal polyamines in a rat small intestine ex vivo model. J Gastroenterol Hepatol 18:554–559. doi:10.1046/j.1440-1746.2003.03020.x