Mainstream smoke levels of volatile organic compounds in 50 U.S. domestic cigarette brands smoked with the ISO and Canadian intense protocols

Nicotine and Tobacco Research

Volumn 18, Issue 9, 2016, Pages 1886-1894

  Pazo, Daniel Y ^a   Moliere, Fallon ^a   Sampson, Maureen M ^a   Reese, Christopher M ^a   Agnew Heard, Kimberly A ^b   Walters, Matthew J ^b   Holman, Matthew R ^b   Blount, Benjamin C ^a   Watson, Clifford H ^a   Chambers, David M ^a  

^a NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^b CENTER FOR TOBACCO PRODUCTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BUTADIENE; 2,6 DIMETHYLFURAN; ACRYLONITRILE; CARBONYL DERIVATIVE; CIGARETTE SMOKE; FURAN; NITRO DERIVATIVE; NITROMETHANE; UNCLASSIFIED DRUG; VINYL CHLORIDE; VOLATILE ORGANIC COMPOUND; AIR POLLUTANT; SMOKE;

ARTICLE; CANADIAN; CLINICAL PROTOCOL; CONTROLLED STUDY; CORRELATION COEFFICIENT; GAS CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; PRIORITY JOURNAL; PYROLYSIS; SMOKE; SOLID PHASE MICROEXTRACTION; UNITED STATES; AIR POLLUTANT; ANALYSIS; CHEMISTRY; KENTUCKY; MASS FRAGMENTOGRAPHY; PACKAGING; PROCEDURES; SMOKING; STANDARD; TOBACCO;

AIR POLLUTANTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; KENTUCKY; PRODUCT LABELING; REFERENCE STANDARDS; SMOKE; SMOKING; TOBACCO; UNITED STATES; VOLATILE ORGANIC COMPOUNDS;

EID: 84988862105     PISSN: 14622203     EISSN: 1469994X     Source Type: Journal    
DOI: 10.1093/ntr/ntw118     Document Type: Article

References (28)

1. Baker RR, Bishop LJ. The pyrolysis of tobacco ingredients. J Anal Appl Pyrol. 2004;71:223-311.
2. Fowles J, Dybing E. Application of toxicological risk assessment principles to the chemical constituents of cigarette smoke. Tob Control. 2003;12:424-430.
3. Mogel I, Baumann S, Bohme A, et al. The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation. Toxicology. 2011;289:28-37.
4. Xu XH, Freeman NC, Dailey AB, et al. Association between exposure to alkylbenzenes and cardiovascular disease among National Health and Nutrition Examination Survey (NHANES) participants. Int J Occup Env Health. 2009;15:385-391.
5. Grandjean P, Landrigan PJ. Developmental neurotoxicity of industrial chemicals. Lancet. 2006;368:2167-2178.
6. Chambers DM, Ocariz JM, McGuirk MF, et al. Impact of cigarette smoking on Volatile Organic Compound (VOC) blood levels in the U.S. Population: NHANES 2003-2004. Environ Int. 2011;37:1321-1328.
7. Bodnar JA, Morgan WT, Murphy PA, et al. Mainstream smoke chemistry analysis of samples from the 2009 US cigarette market. Regul Toxicol Pharm. 2012;64:35-42.
8. Counts ME, Hsu FS, Tewes FJ. Development of a commercial cigarette "market map" comparison methodology for evaluating new or non-conventional cigarettes. Regul Toxicol Pharm. 2006;46:225-242.
9. Polzin GM, Kosa-Maines RE, Ashley DL, et al. Analysis of volatile organic compounds in mainstream cigarette smoke. Environ Sci Technol. 2007;41:1297-1302.
10. WHO Study Group on Tobacco Product Regulation. The Scientific Basis of Tobacco Product Regulation Preface. Geneva: World Health Organization, 2008. www.who.int/tobacco/global_interaction/tobreg/publications/9789241209519.pdf. Accessed November 25, 2015.
11. Kux L. Harmful and potentially harmful constituents in tobacco products and tobacco smoke; established list. Fed Reg. 2012;77:20034-20037. www.gpo.gov/fdsys/pkg/FR-2012-04-03/pdf/2012-7727.pdf. Accessed November 25, 2015.
12. Bialous SA, Yach D. Whose standard is it, anyway? How the tobacco industry determines the International Organization for Standardization (ISO) standards for tobacco and tobacco products. Tob Control. 2001;10:96-104.
13. Hatsukami DK, Morgan SF, Pickens RW, et al. Situational factors in cigarette-smoking. Addict Behav. 1990;15:1-12.
14. Kozlowski LT, O'Connor RJ. Cigarette filter ventilation is a defective design because of misleading taste, bigger puffs, and blocked vents. Tob Control. 2002;11:I40-I50.
15. Health Canada. Determination of "Tar", Nicotine and Carbon Monoxide in Mainstream Tobacco Smoke. Health Canada, 1999 Official Publication T-155).
16. Maxwell JC. The Maxwell Report: Year End & Fourth Quarter 2011 Sales Estimates for the Cigarette Industry. Richmond, VA: John C. Maxwell, Jr.; 2012.
17. Ashley DL, Beeson MD, Johnson DR, et al. Tobacco-specific nitrosamines in tobacco from U.S. brand and non-U.S. brand cigarettes. Nicotine Tob Res. 2003;5:323-331.
18. Sampson MM, Chambers DM, Pazo DY, et al. Simultaneous analysis of 22 volatile organic compounds in cigarette smoke using gas sampling bags for high-throughput solid-phase microextraction. Anal Chem. 2014;86:7088-7095.
19. De Bo I, Van Langenhove H, Pruuost P, et al. Investigation of the permeability and selectivity of gases and volatile organic compounds for polydimethylsiloxane membranes. J Membrane Sci. 2003;215:303-319.
20. Pankow JF, Luo W, Tavakoli AD, et al. Delivery levels and behavior of 1, 3-butadiene, acrylonitrile, benzene, and other toxic volatile organic compounds in mainstream tobacco smoke from two brands of commercial cigarettes. Chem Res Toxicol. 2004;17:805-813.
21. King B, Borland R. The "low-tar" strategy and the changing construction of Australian cigarettes. Nicotine Tob Res. 2004;6:85-94.
22. Counts ME, Morton MJ, Laffoon SW, et al. Smoke composition and predicting relationships for international commercial cigarettes smoked with three machine-smoking conditions. Regul Toxicol Pharm. 2005;41:185-227.
23. Hoffmann D, Patrianakos C, Brunnemann KD, et al. Chemical studies on tobacco smoke. XXXVI. Chromatographic determination of vinyl chloride in tobacco smoke. Anal Chem. 1976;48:47-50.
24. University of Kentucky Center for Tobacco Reference Products. 3R4F Cigarettes, 2015. https://refcig.uky.edu/client/index.html. Accessed November 25, 2015.
25. Fischer S, Spiegelhalder B, Preussmann R. Preformed tobacco-specific nitrosamines in tobacco-role of nitrate and influence of tobacco type. Carcinogenesis. 1989;10:1511-1517.
26. Hoffmann D, Hoffmann I. The changing cigarette, 1950-1995. J Toxicol Env Health. 1997;50:307-364.
27. Hoffmann D, Rathkamp G. Chemical studies on tobacco smoke III. Primary and secondary nitroalkanes in cigarette smoke. Beitr Tabakforsch. 1968;4:124-134.
28. Burdick D, Benner JF, Burton HR. Thermal decomposition of tobacco IV. Apparent correlations between thermogravimetric data and certain constituents in smoke from chemically-treated tobaccos. Tob Sci. 1969;13:138-141.