Dioscoreophyllum cumminsii (Stapf) Diels leaves halt high-fructose induced metabolic syndrome: Hyperglycemia, insulin resistance, inflammation and oxidative stress

Journal of Ethnopharmacology

Volumn 192, Issue , 2016, Pages 471-479

  Ajiboye, T O ^a   Aliyu, H ^a   Tanimu, M A ^a   Muhammad, R M ^a   Ibitoye, O B ^a  

^a AL HIKMAH UNIVERSITY   (Nigeria)

Author keywords

Dioscoreophyllum cumminsii; Dyslipidemia; High fructose diet; Inflammation; Insulin resistance; Metabolic syndrome; Oxidative stress

Indexed keywords

ADIPONECTIN; CATALASE; CHOLESTEROL; DIOSCOREOPHYLLUM CUMMINSII EXTRACT; DISTILLED WATER; FRUCTOSE; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 6; INTERLEUKIN 8; LEPTIN; LIPID HYDROPEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; METFORMIN; PLANT EXTRACT; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTIDIABETIC AGENT; ANTIINFLAMMATORY AGENT; ANTILIPEMIC AGENT; ANTIOXIDANT; AUTACOID; BIOLOGICAL MARKER; GLUCOSE BLOOD LEVEL; LIPID; SOLVENT; WATER;

ABDOMINAL CIRCUMFERENCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; ATHEROGENESIS; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; DIET THERAPY; DIOSCOREOPHYLLUM CUMMINSII; DNA FRAGMENTATION; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HEART INDEX; HYPERGLYCEMIA; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; MALE; MEDICINAL PLANT; METABOLIC SYNDROME X; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; ANIMAL; BLOOD; CHEMICALLY INDUCED; CHEMISTRY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; DYSLIPIDEMIAS; ISOLATION AND PURIFICATION; LIPID PEROXIDATION; LIVER; MENISPERMACEAE; METABOLISM; OBESITY; PATHOLOGY; PHYTOTHERAPY; PROTEIN CARBONYLATION; TIME FACTOR; WEIGHT GAIN; WISTAR RAT;

ADIPOSITY; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BIOMARKERS; BLOOD GLUCOSE; DISEASE MODELS, ANIMAL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DYSLIPIDEMIAS; FRUCTOSE; HYPOGLYCEMIC AGENTS; HYPOLIPIDEMIC AGENTS; INFLAMMATION MEDIATORS; INSULIN; INSULIN RESISTANCE; LIPID PEROXIDATION; LIPIDS; LIVER; MALE; MENISPERMACEAE; METABOLIC SYNDROME X; OXIDATIVE STRESS; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; PLANTS, MEDICINAL; PROTEIN CARBONYLATION; RATS, WISTAR; SOLVENTS; TIME FACTORS; WATER; WEIGHT GAIN;

EID: 84988805367     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.08.024     Document Type: Article

References (47)

1. Adesina, S., Harborne, J., Phillipson, J., The isolation of quaternary alkaloids from the leaves of Dioscoreophyllum cumminsii (Stapf) Diels. Planta Med. 33 (2009), 217–222.
2. Aebi, H., Catalase in vitro. Methods Enzym. 105 (1984), 121–126.
3. Ajboye, T.O., Yakubu, M.T., Salau, A.K., Oladiji, A.T., Akanji, M.A., Okogun, J.I., Antioxidant and drug detoxification potential of aqueous extract of Annona senegalensis leaves in carbon tetrachloride-induced hepatocellular damage. Pharm. Biol. 48 (2010), 1361–1370.
4. Ajiboye, T.O., In vivo antioxidant potentials of Piliostigma thonningii (Schum) leaves: studies on hepatic marker enzyme, antioxidant system, drug detoxifying enzyme and lipid peroxidation. Hum. Exp. Toxicol. 30 (2011), 55–62.
5. Ajiboye, T.O., Raji, H.O., Adeleye, A.O., Adigun, N.S., Giwa, O.B., Ojewuyi, O.B., Oladiji, A.T., Hibiscus sabdariffa calyx palliates insulin resistance, hyperglycemia, dyslipidemia and oxidative rout in fructose-induced metabolic syndrome rats. J. Sci. Food Agric, 2015, 10.1002/jsfa.7254.
6. Ajiboye, T.O., Salau, A.K., Yakubu, M.T., Oladiji, A.T., Akanji, M.A., Okogun, J.I., Acetaminophen perturbed redox homeostasis in Wistar rat liver: protective role of aqueous Pterocarpus osun leaf extract. Drug Chem. Toxicol. 33 (2010), 77–87.
7. Ajiboye, T.O., Yakubu, M.T., Oladiji, A.T., Electrophilic and reactive oxygen species detoxification potentials of chalcone dimers is mediated by redox transcription factor Nrf-2. J.Biochem. Mol. Toxicol.(28), 2014, 11–22.
8. Awazawa, M., Ueki, K., Inabe, K., Yamauchi, T., Kubota, N., Kaneko, K., Kobayashi, M., Iwane, A., Sasako, T., Okazaki, Y., Ohsugi, M., Takamoto, I., Yamashita, S., Asahara, H., Akira, S., Kasuga, M., Kadowaki, T., Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab. 13 (2011), 401–412.
9. Aydin, S., Aksoy, A., Aydin, S., Kalayci, M., Yilmaz, M., Kuloglu, T., Citil, C., Catak, Z., Today's and yesterday's of pathophysiology: Biochemistry of metabolic syndrome and animal models. Nutrition 30 (2014), 1–9.
10. Bettaieb, A., Vazquez Prieto, M. a, Rodriguez Lanzi, C., Miatello, R.M., Haj, F.G., Fraga, C.G., Oteiza, P.I., (-)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress. Free Radic. Biol. Med. 72 (2014), 247–256.
11. Burton, K., A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 62 (1956), 315–323.
12. Chen, K.-N., Peng, W.-H., Hou, C.-W., Chen, C.-Y., Chen, H.-H., Kuo, C.-H., Korivi, M., Codonopsis javanica root extracts attenuate hyperinsulinemia and lipid peroxidation in fructose-fed insulin resistant rats. J. Food Drug Anal. 21 (2013), 347–355.
13. Chen, Q., Reis, S.E., Kammerer, C., Craig, W., McNamara, D.M., Holubkov, R., Sharaf, B.L., Sopko, G., Pauly, D.F., Merz, C.N.B., Kamboh, M.I., Association of anti-oxidized LDL and candidate genes with severity of coronary stenosis in the Women's Ischemia Syndrome Evaluation study. J. Lipid Res. 52 (2011), 801–807.
14. National Research Council (US) Committee, Guide for the Care and Use of Laboratory Animals. Eighth, 2011, 118.
15. Das, U.N., Sucrose, fructose, glucose and their link to metabolic syndrome and cancer. Nutrition 31 (2014), 249–257.
16. Ellman, G.L., Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82 (1959), 70–77.
17. Fernández-Sánchez, A., Madrigal-Santillán, E., Bautista, M., Esquivel-Soto, J., Morales-González, Á., Esquivel-Chirino, C., Durante-Montiel, I., Sánchez-Rivera, G., Valadez-Vega, C., Morales-González, J.A., Inflammation, oxidative stress, and obesity. Int. J. Mol. Sci., 2011.
18. Fonseca-Alaniz, M.H., Takada, J., Alonso-Vale, M.I.C., Lima, F.B., Adipose tissue as an endocrine organ: from theory to practice. J. Pediatr. (Rio. J.) 83 (2007), S192–S203.
19. Friedewald, W.T., Levy, R.I., Fredrickson, D.S., Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18 (1972), 499–502.
20. Han, T.S., Lean, M., Metabolic syndrome. Medicine 39 (2010), 24–31.
21. Hissin, P.J., Hilf, R., A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74 (1976), 214–226.
22. Ibrahim, M.A., Amin, E.F., Ibrahim, S.A., Abdelzaher, W.Y., Abdelrahman, A.M., Montelukast and irbesartan ameliorate metabolic and hepatic disorders in fructose-induced metabolic syndrome in rats. Eur. J. Pharmacol. 724 (2014), 204–210.
23. Kang, M.J., Lee, E.K., Lee, S.S., Effects of two P/S ratios with same peroxidizability index value and antioxidants supplementation on serum lipid concentration and hepatic enzyme activities of rats. Clin. Chim. Acta 350 (2004), 79–87.
24. Kayamori, F., Igarashi, K., Effects of dietary nasunin on the serum cholesterol level in rats. Biosci. Biotechnol. Biochem. 58 (1994), 570–571.
25. Ko, B.J., Park, K.H., Mantzoros, C.S., Diet patterns, adipokines, and metabolism: where are we and what is next?. Metabolism 63 (2014), 168–177.
26. Levine, R.L., Garland, D., Oliver, C.N., Amici, A., Clement, I., Determination of carbonyl content in oxidatively modified proteins. Methods Enzym. 186 (1990), 464–478.
27. Marek, G., Pannu, V., Shanmugham, P., Pancione, B., Mascia, D., Crosson, S., Ishimoto, T., Sautin, Y.Y., Adiponectin resistance and proinflammatory changes in the visceral adipose tissue induced by fructose consumption via ketohexokinase-dependent pathway. Diabetes 64 (2015), 508–518.
28. Misra, H.P., Fridovich, I., The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem 247 (1972), 3170–3175.
29. Mohammadi, A., Gholamhoseinian, A., Fallah, H., Zataria multiflora increases insulin sensitivity and PPARγ gene expression in high fructose fed insulin resistant rats. Iran. J. Basic Med. Sci., 17, 2014 263–70.
30. Musi, N., Guardado-Mendoza, R., Adipose Tissue as an Endocrine Organ. Cell. Endocrinol. Health Dis., 2014, 229–237.
31. Novelli, E.L.B., Diniz, Y.S., Galhardi, C.M., Ebaid, G.M.X., Rodrigues, H.G., Mani, F., Fernandes, A.A.H., Cicogna, A.C., Novelli Filho, J.L.V.B., Anthropometrical parameters and markers of obesity in rats. Lab. Anim. 41 (2007), 111–119.
32. Oliver-Bever, B., Medicinal Plants in Tropical West Africa. 1986, Cambridge University Press.
33. Oloyede, H.O.B., Ajiboye, T.O., Komolafe, Y.O., Salau, A.K., Polyphenolic extract of Blighia sapida arilli prevents N-nitrosodiethylamine-mediated oxidative onslaught on microsomal protein, lipid and DNA. Food Biosci. 1 (2013), 48–56.
34. Oloyede, H.O.B., Bello, T.O., Ajiboye, T.O., Salawu, M.O., Antidiabetic and antidyslipidemic activities of aqueous leaf extract of Dioscoreophyllum cumminsii (Stapf) Diels in alloxan-induced diabetic rats. J. Ethnopharmacol. 166 (2015), 313–322.
35. Oloyede, O.B., Ajiboye, T.O., Abdussalam, A.F., Adeleye, A.O., Blighia sapida leaves halt elevated blood glucose, dyslipidemia and oxidative stress in alloxan-induced diabetic rats. J. Ethnopharmacol. 157 (2014), 309–319.
36. Oron-Herman, M., Kamari, Y., Grossman, E., Yeger, G., Peleg, E., Shabtay, Z., Shamiss, A., Sharabi, Y., Metabolic syndrome: comparison of the two commonly used animal models. Am. J. Hypertens. 21 (2008), 1018–1022.
37. Panchal, S.K., Wong, W.Y., Kauter, K., Ward, L.C., Brown, L., Caffeine attenuates metabolic syndrome in diet-induced obese rats. Nutrition 28 (2012), 1055–1062.
38. Prakash, P., Singh, V., Jain, M., Rana, M., Khanna, V., Barthwal, M.K., Dikshit, M., Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat. Eur. J. Pharmacol. 727 (2014), 15–28.
39. Rabie, E.M., Heeba, G.H., Abouzied, M.M., Khalifa, M.M.A., Comparative effects of Aliskiren and Telmisartan in high fructose diet-induced metabolic syndrome in rats. Eur. J. Pharmacol. 760 (2015), 145–153.
40. Reilly, C.A., Aust, S.D., Measurement of lipid peroxidation. Curr. Protoc. Toxicol., 2001 (Chapter 2), (Unit 2.4).
41. Samson, S.L., Garber, A.J., Metabolic syndrome. Endocrinol. Metab. Clin. North Am., 2014.
42. Scarpace, P.J., Zhang, Y., Leptin resistance: a prediposing factor for diet-induced obesity. Am. J. Physiol. Regul. Integr. Comp. Physiol. 296 (2009), R493–R500.
43. Singh, P., Peterson, T.E., Sert-Kuniyoshi, F.H., Glenn, J.A., Davison, D.E., Romero-Corral, A., Pusalavidyasagar, S., Jensen, M.D., Somers, V.K., Leptin signaling in adipose tissue: role in lipid accumulation and weight gain. Circ. Res. 111 (2012), 599–603.
44. Troupin, G., 1962. Monographie des Menispermaceae africaines. s.n., S.l.
45. Veličković, N., Djordjevic, A., Vasiljević, A., Bursać, B., Milutinović, D.V., Matić, G., Tissue-specific regulation of inflammation by macrophage migration inhibitory factor and glucocorticoids in fructose-fed Wistar rats. Br. J. Nutr. 110 (2013), 456–465.
46. Vickers, A.J., Which botanicals or other unconventional anticancer agents should we take to clinical trial?. J. Soc. Integr. Oncol. 5 (2007), 125–129.
47. Wang, O., Wang, O., Liu, J., Cheng, Q., Guo, X., Wang, Y., Zhao, L., Zhou, F., Effects of ferulic acid and γ -oryzanol on high- fat and high-fructose diet-induced metabolic syndrome in rats effects of ferulic acid and γ -oryzanol on high-fat and high-fructose diet-induced metabolic syndrome in rats. PLoS One 10 (2015), 1–14.