Increased risk of cognitive impairment in patients with components of metabolic syndrome

Medicine (United States)

Volumn 95, Issue 36, 2016, Pages

  Tsai, Chia Kuang ^a,b   Kao, Tung Wei ^a,b,c   Lee, Jiunn Tay ^a   Wu, Chen Jung ^c   Hueng, Dueng Yuan ^a,b   Liang, Chih Sung ^a   Wang, Gia Chi ^c   Yang, Fu Chi ^a   Chen, Wei Liang ^a,b,c  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c Division of Family Medicine   (Taiwan)

Author keywords

Cognitive impairment; Digit symbol substitution test; Metabolic syndrome

Indexed keywords

GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; CLINICAL FEATURE; COGNITION; COGNITIVE DEFECT; DIGIT SYMBOL SUBSTITUTION TEST; ELEVATED BLOOD PRESSURE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; PATIENT RISK; PRIORITY JOURNAL; TASK PERFORMANCE; TREND STUDY; TRIACYLGLYCEROL BLOOD LEVEL; BLOOD; COGNITIVE DYSFUNCTION; HYPERGLYCEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; MIDDLE AGED; NEUROPSYCHOLOGICAL TEST; NUTRITION; OBESITY, ABDOMINAL; UNITED STATES;

AGED; CHOLESTEROL, HDL; COGNITIVE DYSFUNCTION; FEMALE; HUMANS; HYPERGLYCEMIA; HYPERTENSION; HYPERTRIGLYCERIDEMIA; MALE; METABOLIC SYNDROME X; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; NUTRITION SURVEYS; OBESITY, ABDOMINAL; UNITED STATES;

EID: 84988369685     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000004791     Document Type: Article

References (38)

1. Brookmeyer R, Gray S. Methods for projecting the incidence and prevalence of chronic diseases in ageing populations: application to Alzheimer's disease. Stat Med 2000;19:1481-93.
2. Jorm AF, Jolley D. The incidence of dementia: a meta-analysis. Neurology 1998;51:728-33.
3. McCrimmon RJ, Ryan CM, Frier BM. Diabetes and cognitive dysfunction. Lancet 2012;379:2291-9.
4. Knopman D, Boland LL, Mosley T, et al. Cardiovascular risk factors and cognitive decline in middle-aged adults. Neurology 2001;56:42-8.
5. Yaffe K, Lindquist K, Schwartz AV, et al. Advanced glycation end product level, diabetes, and accelerated cognitive aging. Neurology 2011;77:1351-6.
6. Yaffe K, Ackerson L, Kurella Tamura M, et al. Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study. J Am Geriatr Soc 2010;58:338-45.
7. Mottillo S, Filion KB, Genest J, et al. The metabolic syndrome and cardiovascular risk a systematic review and meta-analysis. J Am Coll Cardiol 2010;56:1113-32.
8. Hotamisligil GS. The role of TNF (and TNF receptors in obesity and insulin resistance. J Intern Med 1999;245:621-5.
9. Gunstad J, Paul RH, Cohen RA, et al. Elevated body mass index is associated with executive dysfunction in otherwise healthy adults. Compr Psychiatry 2007;48:57-61.
10. Dahl AK, Hassing LB, Fransson EI, et al. Body mass index across midlife and cognitive change in late life. Int J Obes 2013;37:296-302.
11. Novak V, Hajjar I. The relationship between blood pressure and cognitive function. Nat Rev Cardiol 2010;7:686-98.
12. KochM, Jensen MK. HDL-cholesterol and apolipoproteins in relation to dementia. Curr Opin Lipidol 2016;27:76-87.
13. Bethesda, MD. National Center for Health Statistics. National Health and Nutrition Examination Survey (NHANES), 1999-2000. Available: http://wwwn. cdc. gov/nchs/nhanes/search/nhanes99-00. aspx. [Accessed December 12, 2015].
14. Bethesda, MD. National Center for Health Statistics. National Health and Nutrition Examination Survey (NHANES), 2001-2002. Available: http://wwwn. cdc. gov/nchs/nhanes/search/nhanes01-02. aspx. [Accessed December 12, 2015].
15. Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis andmanagement of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005;112:2735-52.
16. Parkin AJ, Java RI. Deterioration of frontal lobe function in normal aging: influences of fluid intelligence versus perceptual speed. Neuropsychology 1999;13:539-45.
17. Rosano C, Simonsick EM, Harris TB, et al. Association between physical and cognitive function in healthy elderly: the health, aging and body composition study. Neuroepidemiology 2005;24:8-14.
18. Kuo HK, Leveille SG, Yu YH, et al. Cognitive function, habitual gait speed, and late-life disability in the National Health and Nutrition Examination Survey (NHANES) 1999-2002. Gerontology 2007;53: 102-10.
19. Cheng YJ, Gregg EW, Kahn HS, et al. Peripheral insensate neuropathy-a tall problem for US adults? Am J Epidemiol 2006;164:873-80.
20. Yaffe K, Falvey C, Hamilton N, et al. Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia. Arch Neurol 2012;69:1170-5.
21. Baker LD, Cross DJ, Minoshima S, et al. Insulin resistance and Alzheimer-like reductions in regional cerebral glucose metabolism for cognitively normal adults with prediabetes or early type 2 diabetes. Arch Neurol 2011;68:51-7.
22. Frisardi V, Solfrizzi V, Capurso C, et al. Is insulin resistant brain state a central feature of the metabolic-cognitive syndrome? J Alzheimers Dis 2010;21:57-63.
23. Matsuzaki T, Sasaki K, Tanizaki Y, et al. Insulin resistance is associated with the pathology of Alzheimer disease The Hisayama Study. Neurology 2010;75:764-70.
24. Unger J, Livingston J, Moss A. Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects. Prog Neurobiol 1991;36:343-62.
25. Moloney AM, Griffin RJ, Timmons S, et al. Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling. Neurobiol Aging 2010;31: 224-43.
26. Brownlee M. Biochemistry and molecular cell biology of diabetic complications. Nature 2001;414:813-20.
27. de la Monte SM. Insulin resistance and Alzheimer's disease. BMB Rep 2009;42:475-81.
28. Willette AA, Johnson SC, Birdsill AC, et al. Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Alzheimers Dement 2015;11:504-10. e1.
29. Gifford KA, Badaracco M, Liu D, et al. Blood pressure and cognition among older adults: a meta-analysis. Arch Clin Neuropsychol 2013;28: 649-64.
30. Launer LJ, Ross GW, Petrovitch H, et al. Midlife blood pressure and dementia: the Honolulu-Asia aging study. Neurobiol Aging 2000;21: 49-55.
31. Petrova M, Prokopenko S, Pronina E, et al. Diabetes type 2, hypertension and cognitive dysfunction in middle age women. J Neurol Sci 2010;299: 39-41.
32. Gelber RP, Ross GW, Petrovitch H, et al. Antihypertensive medication use and risk of cognitive impairment: the Honolulu-Asia Aging Study. Neurology 2013;81:888-95.
33. Shah NS, Vidal JS, Masaki K, et al. Midlife blood pressure, plasma betaamyloid, and the risk for Alzheimer disease: the Honolulu Asia Aging Study. Hypertension 2012;59:780-6.
34. Nagai M, Hoshide S, Ishikawa J, et al. Ambulatory blood pressure as an independent determinant of brain atrophy and cognitive function in elderly hypertension. J Hypertens 2008;26:1636-41.
35. Strassburger TL, Lee HC, Daly EM, et al. Interactive effects of age and hypertension on volumes of brain structures. Stroke 1997;28:1410-7.
36. Henskens LH, Kroon AA, van Oostenbrugge RJ, et al. Associations of ambulatory blood pressure levels with white matter hyperintensity volumes in hypertensive patients. J Hypertens 2009;27:1446-52.
37. de Groot JC, de Leeuw FE, Oudkerk M, et al. Cerebral white matter lesions and cognitive function: the Rotterdam Scan Study. Ann Neurol 2000;47:145-51.
38. Tchistiakova E, Anderson ND, Greenwood CE, et al. Combined effects of type 2 diabetes and hypertension associated with cortical thinning and impaired cerebrovascular reactivity relative to hypertension alone in older adults. Neuroimage Clin 2014;5:36-41.