A laboratory test based on determination of cytokine profiles: A promising assay to identify exposition to contact allergens and predict the clinical outcome in occupational allergic contact dermatitis

BMC Immunology

Volumn 16, Issue 1, 2015, Pages

  Bordignon, Valentina ^a   Palamara, Francesca ^a   Altomonte, Giorgia ^a   Sperduti, Isabella ^b   Pietravalle, Mario ^a   Cavallotti, Claudia ^a   Cordiali Fei, Paola ^a   Fuggetta, Maria Pia ^c   Cristaudo, Antonio ^a   Ensoli, Fabrizio ^a  

^a SAN GALLICANO DERMATOLOGICAL INSTITUTE   (Italy)

^b REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^c INSTITUTE OF TRANSLATIONAL PHARMACOLOGY   (Italy)

Author keywords

Allergic contact dermatitis; Cytokines; ELISpot; Nickel; Occupation; Para phenylenediamine; Patch test

Indexed keywords

CONTACT ALLERGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; NICKEL SULFATE; PHENYLENEDIAMINE; 4-PHENYLENEDIAMINE; ALLERGEN; HAIR DYE; NICKEL; PHENYLENEDIAMINE DERIVATIVE;

ADULT; ARTICLE; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSPOT ASSAY; FALSE POSITIVE RESULT; FEMALE; HUMAN; LABORATORY TEST; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; PATCH TEST; PERIPHERAL BLOOD MONONUCLEAR CELL; PREDICTIVE VALUE; SENSITIVITY AND SPECIFICITY; SKIN ALLERGY; YOUNG ADULT; ADVERSE EFFECTS; CELL CULTURE; DERMATITIS, ALLERGIC CONTACT; DERMATITIS, OCCUPATIONAL; IMMUNOLOGY; METABOLISM; PROCEDURES; PROGNOSIS; T LYMPHOCYTE;

ADULT; ALLERGENS; CELLS, CULTURED; CLINICAL LABORATORY TECHNIQUES; DERMATITIS, ALLERGIC CONTACT; DERMATITIS, OCCUPATIONAL; ENZYME-LINKED IMMUNOSPOT ASSAY; FEMALE; HAIR DYES; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-10; MALE; MIDDLE AGED; NICKEL; OCCUPATIONAL EXPOSURE; PHENYLENEDIAMINES; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SENSITIVITY AND SPECIFICITY; T-LYMPHOCYTES; YOUNG ADULT;

EID: 84988299010     PISSN: None     EISSN: 14712172     Source Type: Journal    
DOI: 10.1186/s12865-015-0066-3     Document Type: Article

References (39)

1. Garrigue JL, Nicolas JF, Fraginals R, Benezra C, Bour H, Schmitt D. Optimization of the mouse ear swelling test for in vivo and in vitro studies of weak contact sensitizers. Contact Dermatitis. 1994;30:231-7.
2. Gerberick GF, Ryan CA, Dearman RJ, Kimber I. Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals. Methods. 2007;41:54-60.
3. Xie Z, Hayakawa R, Sugiura M, Kojima H, Konishi H, Ichihara G, et al. Experimental study on skin sensitization potencies and cross-reactivities of hair-dye-related chemicals in guinea pigs. Contact Dermatitis. 2000;42:270-5.
4. Sosted H, Menne T, Johansen JD. Patch test dose-response study of p-phenylenediamine: thresholds and anatomical regional differences. Contact Dermatitis. 2006;54:145-9.
5. Malvestio A, Bovenzi M, Hoteit M, Belloni Fortina A, Peserico A, Corradin MT, et al. p-Phenylenediamine sensitization and occupation. Contact Dermatitis. 2011;64:37-42.
6. DeLeo VA. P-Phenylenediamine. Dermatitis. 2006;17:53-5.
7. Sosted H, Hesse U, Menn'e T, Andersen KE, Johanson JD. Contact dermatitis to hair dyes in an adult Danish population - an interview based study. Br J Dermatol. 2005;153:132-5.
8. Laing ME, Powell FC, O'Sullivan D. The influence of contact dermatitis on career change in hairdressers. Contact Dermatitis. 2006;54:218-9.
9. Ryberg K, Goossens A, Isaksson M, Ryberg K, Goossens A, Isaksson M, et al. Is contact allergy to disperse dyes and related substances associated with textile dermatitis? Br J Dermatol. 2009;160:107-15.
10. Nardelli A, Taveirne M, Drieghe J, Carbonez A, Degreef H, Goossens A. The relation between the localization of foot dermatitis and the causative allergens in shoes: a 13-year retrospective study. Contact Dermatitis. 2005;53:201-6.
11. Malinauskiene L, Zimerson E, Bruze M, Ryberg K, Isaksson M. Patch testing with the textile dyes disperse orange 1 and disperse yellow 3 and some of their potential metabolites, and simultaneous reactions to para-amino compounds. Contact Dermatitis. 2012;67:130-40.
12. Valks R, Conde-Salazar L, Malfeito J, Ledo S. Contact dermatitis in hairdressers, 10 years later: patch-test results in 300 hairdressers (1994 to 2003) and comparison with previous study. Dermatitis. 2005;16:28-31.
13. De Cuyper C. Permanent makeup: indications and complications. Clin Dermatol. 2008;26:30-4.
14. Kluger N. Cutaneous complications related to permanent decorative tattooing. Expert Rev Clin Immunol. 2010;6:363-71.
15. Patel S, Basketter DA, Jefferies D, White IR, Rycroft RJ, McFadden JP, et al. Patch test frequency to p-phenylenediamine: follow up over the last 6 years. Contact Dermatitis. 2007;56:35-7.
16. Picardo M, Cannistraci C, Cristaudo A, De Luca C, Santucci B. Study on cross-reactivity to the para group. Dermatologica. 1990;181:104-8.
17. Coulter EM, Jenkinson C, Farrell J, Lavergne SN, Pease C, White A, et al. Measurement of CD4+ and CD8+ T-lymphocyte cytokine secretion and gene expression changes in p-phenylenediamine allergic patients and tolerant individuals. J Invest Dermatol. 2010;130:161-74.
18. Mori T, Kabashima K, Yoshiki R, Sugita K, Shiraishi N, Onoue A, et al. Cutaneous hypersensitivities to hapten are controlled by IFN-g-upregulated keratinocyte Th1 chemokines and IFN-g-downregulated Langerhans cell Th2 chemokines. J Invest Dermatol. 2008;128:1719-27.
19. Gamerdinger K, Moulon C, Karp DR, Van Bergen J, Koning F, Wild D, et al. A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel. J Exp Med. 2003;197:1345-53.
20. Sieben S, Kawakubo Y, Al Masaoudi T, Merk HF, Blömeke B. Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific alphabeta human T-cell clones. J Allergy Clin Immunol. 2002;109:1005-11.
21. Akiba H, Kehren J, Ducluzeau MT, Krasteva M, Horand F, Kaiserlian D, et al. Skin inflammation during contact hypersensitivity is mediated by early recruitment of CD8+ T cytotoxic 1 cells inducing keratinocyte apoptosis. J Immunol. 2002;168:3079-87.
22. Cavani A, Nasorri F, Ottaviani C, Sebastiani S, De Pita O, Girolomoni G. Human CD25+ regulatory T cells maintain immune tolerance to nickel in healthy, nonallergic individuals. J Immunol. 2003;171:5760-8.
23. Cavani A, Nasorri F, Prezzi C, Sebastiani S, Albanesi C, Girolomoni G. Human CD4+ T lymphocytes with remarkable regulatory functions on dendritic cells and nickel-specific Th1 immune responses. J Invest Dermatol. 2000;114:295-302.
24. Bordignon V, Palamara F, Cordiali-Fei P, Vento A, Aiello A, Picardo M, et al. Nickel, palladium and rhodium induced IFN-gamma and IL-10 production as assessed by in vitro ELISpot-analysis in contact dermatitis patients. BMC Immunol. 2008;9:19.
25. Traidl-Hoffmann C, Ring J. Is there an in vitro test for type IV allergy discriminating between sensitization and allergic disease? Clin Exp Allergy. 2008;38:1412-5.
26. Rietshel RL, Fowler Jr JF. Practical aspects of patch testing. In: Rietshel RL, Fowler Jr JF, editors. Fisher's Contact Dermatitis. 5th ed. Philadelphia: Lipincott Williams and Wilkins; 2001. p. 9-26.
27. Coulter EM, Farrell J, Mathews KL, Maggs JL, Pease CK, Lockley DJ, et al. Activation of human dendritic cells by p-phenylenediamine. J Pharmacol Exp Ther. 2007;320:885-92.
28. Devos SA, Van Der Valk PG. Epicutaneous patch testing. Eur J Dermatol. 2002;12:506-13.
29. Thyssen JP, Menné T, Nielsen NH, Linneberg A. Is there a risk of active sensitization to PPD by patch testing the general population? Contact Dermatitis. 2007;57:133-4.
30. Jung P, Sesztak-Greinecker G, Wantke F, Götz M, Jarisch R, Hemmer W. A painful experience: black henna tattoo causing severe, bullous contact dermatitis. Contact Dermatitis. 2006;54:219-20.
31. Borg L, Christensen JM, Kristiansen J, Nielsen NH, Menné T, Poulsen LK. Nickel-induced cytokine production from mononuclear cells in nickel-sensitive individuals and controls. Cytokine profiles in nickel-sensitive individuals with nickel allergy-related hand eczema before and after nickel challenge. Arch Dermatol Res. 2000;292:285-91.
32. Büdinger L, Hertl M. Immunologic mechanisms in hypersensitivity reactions to metal ions: an overview. Allergy. 2000;55:108-15.
33. Rustemeyer T, von Blomberg BM, van Hoogstraten IM, Bruynzeel DP, Scheper RJ. Analysis of effector and regulatory immune reactivity to nickel. Clin Exp Allergy. 2004;34:1458-66.
34. Denman EJ, Denman AM. The lymphocyte transformation test and gold hypersensitivity. Ann Rheum Dis. 1968;27:582-9.
35. Thomas P, Bandl WD, Maier S, Summer B, Przybilla B. Hypersensitivity to titanium osteosynthesis with impaired fracture healing, eczema, and T-cell hyperresponsiveness in vitro: case report and review of the literature. Contact Dermatitis. 2006;55:199-202.
36. Kneilling M, Caroli U, Grimmel C, Fischer J, Eichner M, Wieder T, et al. Para-phenylenediamine-specific lymphocyte activation test: a sensitive in vitro assay to detect para-phenylenediamine sensitization in patients with severe allergic reactions. Exp Dermatol. 2010;19:435-41.
37. Coulter EM, Jenkinson C, Wu Y, Farrell J, Foster B, Smith A, et al. Activation of T-cells from allergic patients and volunteers by p-phenylenediamine and Bandrowski's base. J Invest Dermatol. 2008;128:897-905.
38. Jakobson E, Masjedi K, Ahlborg N, Lundeberg L, Karlberg AT, Scheynius A. Cytokine production in nickel-sensitized individuals analysed with enzyme-linked immunospot assay: possible implication for diagnosis. Br J Dermatol. 2002;147:442-9.
39. Lindemann M, Böhmer J, Zabel M, Grosse-Wilde H. ELISpot: a new tool for the detection of nickel sensitization. Clin Exp Allergy. 2003;33:992-8.