Antibodies and protection against invasive Salmonella disease

Frontiers in Immunology

Volumn 5, Issue DEC, 2014, Pages

  MacLennan, Calman A ^a,b  

^a NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Antibody; Invasive; Nontyphoidal; Salmonella; Vaccine

Indexed keywords

BACTERIAL LOAD; BINDING AFFINITY; CELL PHAGOCYTOSIS; DISEASE CLEARANCE; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOMODULATION; MACROPHAGE; MALARIA; NONHUMAN; NOTE; TYPHOID FEVER;

EID: 84987788911     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00635     Document Type: Note

References (28)

1. MacLennan CA, Levine MM. Invasive nontyphoidal Salmonella disease in Africa: current status. Expert Rev Anti Infect Ther (2013) 11(5):443-6. doi: 10.1586/eri.13.27
2. Feasey NA, Dougan G, Kingsley RA, Heyderman RS, Gordon MA. Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa. Lancet (2012) 379(9835):2489-99. doi:10.1016/S0140-6736(11)61752-2
3. Mastroeni P, Grant A, Restif O, Maskell D. A dynamic view of the spread and intracellular distribution of Salmonella enterica. Nat Rev Microbiol (2009) 7(1):73-80. doi:10.1038/nrmicro2034
4. Siggins MK, O'Shaughnessy CM, Pravin J, Cunningham AF, Henderson IR, Drayson MT, et al. Differential timing of antibody-mediated phagocytosis and cell-free killing of invasive African Salmonella allows immune evasion. Eur J Immunol (2014) 44(4):1093-8. doi:10.1002/eji.201343529
5. MacLennan CA, Martin LB, Micoli F. Vaccines against invasive Salmonella disease: current status and future directions. Hum Vaccin Immunother (2014) 10(6):1478-93. doi:10.4161/hv.29054
6. Gonzalez-Fernandez A, Faro J, Fernandez C. Immune responses to polysaccharides: lessons from humans and mice. Vaccine (2008) 26(3):292-300. doi:10.1016/j.vaccine.2007.11.042
7. Vos Q, Lees A, Wu ZQ, Snapper CM, Mond JJ. B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms. Immunol Rev (2000) 176:154-70. doi:10.1034/j.1600-065X.2000.00607.x
8. Sinha K, Mastroeni P, Harrison J, de Hormaeche RD, Hormaeche CE. Salmonella typhimurium aroA, htrA, and aroD htrA mutants cause progressive infections in athymic (nu/nu) BALB/c mice. Infect Immun (1997) 65:1566-9.
9. Siggins MK, Cunningham AF, Marshall JL, Chamberlain JL, Henderson IR, MacLennan CA. Absent bactericidal activity of mouse serum against invasive African nontyphoidal Salmonella results from impaired complement function but not a lack of antibody. J Immunol (2011) 186(4):2365-71. doi:10.4049/jimmunol.1000284
10. Klugman KP, Koornhof HJ, Robbins JB, Le Cam NN. Immunogenicity, efficacy and serological correlate of protection of Salmonella typhi Vi capsular polysaccharide vaccine three years after immunization. Vaccine (1996) 14(5):435-8. doi:10.1016/0264-410X(95)00186-5
11. Fraser A, Paul M, Goldberg E, Acosta CJ, Leibovici L. Typhoid fever vaccines: systematic review and meta-analysis of randomised controlled trials. Vaccine (2007) 25(45):7848-57.
12. MacLennan CA, Gondwe EN, Msefula CL, Kingsley RA, Thomson NR, White SA, et al. The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children. J Clin Invest (2008) 118:1553-62. doi:10.1172/JCI33998
13. Sharma A, Qadri A. Vi polysaccharide of Salmonella typhi targets the prohibitin family of molecules in intestinal epithelial cells and suppresses early inflammatory responses. Proc Natl Acad Sci U S A (2004) 101(50):17492-7. doi:10.1073/pnas.0407536101
14. Raffatellu M, Santos RL, Verhoeven DE, George MD, Wilson RP, Winter SE, et al. Simian immunodeficiency virus-induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut. Nat Med (2008) 14(4):421-8. doi:10.1038/nm1743
15. Wangdi T, Winter SE, Baumler AJ. Typhoid fever: "you can't hit what you can't see". Gut Microbes (2012) 3(2):88-92. doi:10.4161/gmic.18602
16. Kingsley RA, Msefula CL, Thomson NR, Kariuki S, Holt KE, Gordon MA, et al. Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Res (2009) 19:2279-87. doi:10.1101/gr.091017.109
17. Okoro CK, Kingsley RA, Connor TR, Harris SR, Parry CM, Al-Mashhadani MN, et al. Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa. Nat Genet (2012) 44(11):1215-21. doi:10.1038/ng.2423
18. Gondwe EN, Molyneux ME, Goodall M, Graham SM, Mastroeni P, Drayson MT, et al. Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans. Proc Natl Acad Sci U S A (2010) 107(7):3070-5. doi:10.1073/pnas.0910497107
19. Nyirenda TS, Gilchrist JJ, Feasey NA, Glennie SJ, Bar-Zeev N, Gordon MA, et al. Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in malawian children. J Infect Dis (2014) 210(1):56-64. doi:10.1093/infdis/jiu045
20. Trebicka E, Jacob S, Pirzai W, Hurley BP, Cherayil BJ. Role of antilipopolysaccharide antibodies in serum bactericidal activity against Salmonella enterica serovar Typhimurium in healthy adults and children in the United States. Clin Vaccine Immunol (2013) 20(10):1491-8. doi:10.1128/CVI.00289-13
21. MacLennan CA, Gilchrist JJ, Gordon MA, Cunningham AF, Cobbold M, Goodall M, et al. Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults. Science (2010) 328(5977):508-12. doi:10.1126/science.1180346
22. Wells TJ, Whitters D, Sevastsyanovich YR, Heath JN, Pravin J, Goodall M, et al. Increased severity of respiratory infections associated with elevated anti-LPS IgG2 which inhibits serum bactericidal killing. J Exp Med (2014) 211(9):1893-904. doi:10.1084/jem.20132444
23. Goh YS, Necchi F, Rondini S, et al. Bactericidal potential of S. Typhimurium LPS-specific antibodies from HIV-infected African Adults. 8th International Conference on Typhoid Fever and Other Salmonelloses; Dhaka, Bangladesh (2013). p. 12.
24. Okoro CK, Kingsley RA, Quail MA, Kankwatira AM, Feasey NA, Parkhill J, et al. High-resolution single nucleotide polymorphism analysis distinguishes recrudescence and reinfection in recurrent invasive nontyphoidal Salmonella Typhimurium disease. Clin Infect Dis (2012) 54(7):955-63. doi:10.1093/cid/cir1032
25. Mastroeni P, Ugrinovic S, Chandra A, MacLennan C, Doffinger R, Kumararatne DS. Resistance and susceptibility to Salmonella infections: lessons from mice and patients with immunodeficiencies. Rev Med Microbiol (2003) 14:1-10. doi:10.1097/00013542-200304000-00002
26. MacLennan C, Fieschi C, Lammas DA, Picard C, Dorman SE, Sanal O, et al. Interleukin (IL)-12 and IL-23 are key cytokines for immunity against Salmonella in humans. J Infect Dis (2004) 190:1755-7. doi:10.1086/425021
27. Nyirenda TS, Seeley AE, Mandala WL, Drayson MT, MacLennan CA. Early interferon-gamma production in human lymphocyte subsets in response to nontyphoidal Salmonella demonstrates inherent capacity in innate cells. PLoS One (2010) 5(10):e13667. doi:10.1371/journal.pone.0013667
28. Cunnington AJ, de Souza JB, Walther M, Riley EM. Malaria impairs resistance to Salmonella through heme-and heme oxygenase-dependent dysfunctional granulocyte mobilization. Nat Med (2012) 18(1):120-7. doi:10.1038/nm.2601