A rapid, inexpensive and disposable point-of-care blood test for sickle cell disease using novel, highly specific monoclonal antibodies

British Journal of Haematology

Volumn 175, Issue 4, 2016, Pages 724-732

  Quinn, Charles T ^a   Paniagua, Mary C ^a   DiNello, Robert K ^b   Panchal, Anand ^b   Geisberg, Mark ^b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b Silver Lake Research Corporation   (United States)

Author keywords

haemoglobinopathy; lateral flow immunoassay; monoclonal antibody; point of care; sickle cell disease

Indexed keywords

HEMOGLOBIN A; HEMOGLOBIN AC; HEMOGLOBIN AS; HEMOGLOBIN C; HEMOGLOBIN CC; HEMOGLOBIN S; HEMOGLOBIN SC; HEMOGLOBIN VARIANT; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ANIMAL EXPERIMENT; ANTIBODY SPECIFICITY; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; COST CONTROL; CROSS REACTION; DIAGNOSTIC ACCURACY; DISPOSABLE EQUIPMENT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEALTH CARE COST; HEMOGLOBIN ANALYSIS; HEMOGLOBIN SC DISEASE; HUMAN; IMMUNOAFFINITY CHROMATOGRAPHY; LATERAL FLOW IMMUNOCHROMATOGRAPHY; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; PHENOTYPE; POINT OF CARE TESTING; PRIORITY JOURNAL; SICKLE CELL ANEMIA; TEST STRIP; TURNAROUND TIME; VALIDATION PROCESS; ANEMIA, SICKLE CELL; ANIMAL; BLOOD; BLOOD EXAMINATION; DIFFERENTIAL DIAGNOSIS; POINT OF CARE SYSTEM; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SICKLE CELL TRAIT; STANDARDS;

ANEMIA, SICKLE CELL; ANIMALS; ANTIBODIES, MONOCLONAL; DIAGNOSIS, DIFFERENTIAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HEMATOLOGIC TESTS; HUMANS; MICE; POINT-OF-CARE SYSTEMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SICKLE CELL TRAIT;

EID: 84987644067     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.14298     Document Type: Article

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