Periostin is a novel therapeutic target that predicts and regulates glioma malignancy

Neuro-Oncology

Volumn 17, Issue 3, 2015, Pages 372-382

  Mikheev, Andrei M ^a   Mikheeva, Svetlana A ^a   Trister, Andrew D ^a,b   Tokita, Mari J ^a   Emerson, Samuel N ^a   Parada, Carolina A ^a   Born, Donald E ^c   Carnemolla, Barbara ^d   Frankel, Sam ^a   Kim, Deok Ho ^a   Oxford, Rob G ^a   Kosai, Yoshito ^e   Tozer Fink, Kathleen R ^a   Manning, Thomas C ^f   Silber, John R ^a   Rostomily, Robert C ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b SAGE BIONETWORKS   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF GENOA   (Italy)

^e CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Neuroscience Associat   (United States)

Author keywords

Glioma stem cells; Invasion; Malignancy; Periostin; Recurrent glioma

Indexed keywords

ALPHAVBETA5 INTEGRIN; BIOLOGICAL MARKER; CILENGITIDE; F ACTIN; FOCAL ADHESION KINASE; MATRIX METALLOPROTEINASE; TRANSCRIPTION FACTOR RUNX2; VITRONECTIN RECEPTOR; CELL ADHESION MOLECULE; INTEGRIN; POSTN PROTEIN, HUMAN; TUMOR MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CLASSIFICATION; CANCER GRADING; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER SURVIVAL; CANCER TISSUE; CARCINOGENESIS; CARCINOGENICITY; CELL ACTIVITY; CELL ADHESION; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOSKELETON; DISEASE ASSOCIATION; DRUG CYTOTOXICITY; DRUG TARGETING; GENE FUNCTION; GENE SIGNATURE; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PREDICTION; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TUMOR XENOGRAFT; UPREGULATION; ANTAGONISTS AND INHIBITORS; BRAIN NEOPLASMS; GLIOMA; KAPLAN MEIER METHOD; METABOLISM; MORTALITY; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

BIOMARKERS, TUMOR; BRAIN NEOPLASMS; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE, TUMOR; GLIOMA; HUMANS; INTEGRINS; KAPLAN-MEIER ESTIMATE; NEOPLASM GRADING; NEOPLASM INVASIVENESS; UP-REGULATION;

EID: 84987596902     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nou161     Document Type: Article

References (44)

1. Horiuchi K, Amizuka N, Takeshita S, et al. Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. J Bone Miner Res. 1999;14(7):1239-1249.
2. Conway SJ, Izuhara K, Kudo Y, et al. The role of periostin in tissue remodeling across health and disease. Cell Mol Life Sci. 2014;71(7): 1279-1288.
3. Conway SJ, Molkentin JD. Periostin as a heterofunctional regulator of cardiac development and disease. Curr Genomics. 2008;9(8): 548-555.
4. Morra L, Moch H. Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update. Virchows Arch 2011; 459(5):465-475.
5. Ruan K, Bao S, Ouyang G. The multifaceted role of periostin in tumorigenesis. Cell Mol Life Sci. 2009;66(14):2219-2230.
6. Bao S, Ouyang G, Bai X, et al. Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell. 2004;5(4):329-339.
7. Baril P, Gangeswaran R, Mahon PC, et al. Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway. Oncogene. 2007;26(14):2082-2094.
8. Lal A, Lash AE, Altschul SF, et al. A public database for gene expression in human cancers. Cancer Res. 1999;59(21):5403-5407.
9. Tso CL, Shintaku P, Chen J, et al. Primary glioblastomas express mesenchymal stem-like properties. Mol Cancer Res. 2006;4(9): 607-619.
10. Zinn PO, Mahajan B, Sathyan P, et al. Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiforme. PloS One. 2011;6(10):e25451.
11. Wang H, Wang Y, Jiang C. Stromal protein periostin identified as a progression associated and prognostic biomarker in glioma via inducing an invasive and proliferative phenotype. Int J Oncol. 2013;42(5):1716-1724.
12. Mustafa DA, Dekker LJ, Stingl C, et al. A proteome comparison between physiological angiogenesis and angiogenesis in glioblastoma. Mol Cell Proteomics. 2012;11(6):M111 008466.
13. Gillan L, Matei D, Fishman DA, et al. Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility. Cancer Res. 2002;62(18):5358-5364.
14. Zhu M, Saxton RE, Ramos L, et al. Neutralizing monoclonal antibody to periostin inhibits ovarian tumor growth and metastasis. Mol Cancer Ther. 2011;10(8):1500-1508.
15. Wakimoto H, Kesari S, Farrell CJ, et al. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 2009;69(8):3472-3481.
16. Mikheeva SA, Mikheev AM, Petit A, et al. TWIST1 promotes invasion through mesenchymal change in human glioblastoma. Mol Cancer. 2010;9:194.
17. Elias MC, Tozer KR, Silber JR, et al. TWIST is Expressed in Human Gliomas and Promotes Invasion. Neoplasia. 2005;7(9):824-837.
18. Orecchia P, Conte R, Balza E, et al. Identification of a novel cell binding site of periostin involved in tumour growth. Eur J Cancer. 2011;47(14):2221-2229.
19. Mecham BH, Nelson PS, Storey JD. Supervised normalization of microarrays. Bioinformatics. 2010;26(10):1308-1315.
20. Benaglia T, Chauveau D, Hunter DR, et al. Mixtools: An R Package for Analyzing Mixture Models. J Stat Softw. 2009;32(6):1-29.
21. Friedman J, Hastie T, Tibshirani R. Regularization Paths for Generalized Linear Models via Coordinate Descent. J Stat Softw. 2010;33(1):1-22.
22. Reardon DA, Cheresh D. Cilengitide: a prototypic integrin inhibitor for the treatment of glioblastoma and other malignancies. Genes Cancer. 2011;2(12):1159-1165.
23. Stupp R, Hegi ME, Neyns B, et al. Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28(16): 2712-2718.
24. Fujiwara H, Kikkawa Y, Sanzen N, et al. Purification and characterization of human laminin-8. Laminin-8 stimulates cell adhesion and migration through alpha3beta1 and alpha6beta1 integrins. J Biol Chem. 2001;276(20):17550-17558.
25. Li G, Jin R, Norris RA, et al. Periostin mediates vascular smooth muscle cell migration through the integrins alphavbeta3 and alphavbeta5 and focal adhesion kinase (FAK) pathway. Atherosclerosis. 2010;208(2):358-365.
26. Tomar A, Schlaepfer DD. Focal adhesion kinase: switching between GAPs and GEFs in the regulation of cell motility. Curr Opin Cell Biol. 2009;21(5):676-683.
27. Kim DH, Wirtz D. Focal adhesion size uniquely predicts cell migration. FASEB J. 2013;27(4):1351-1361.
28. Verhaak RG, Hoadley KA, Purdom E, et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010;17(1):98-110.
29. Zou H, Hastie T. Regularization and variable selection via the elastic net. J Royal Stat Soc B. 2005;67(2):301-320.
30. Phillips HS, Kharbanda S, Chen R, et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006;9(3):157-173.
31. Cheon DJ, Tong Y, Sim MS, et al. A collagen-remodeling gene signature regulated by TGF-beta signaling is associated with metastasis and poor survival in serous ovarian cancer. Clin Cancer Res. 2014;20(3):711-723.
32. Kudo A. Periostin in fibrillogenesis for tissue regeneration: periostin actions inside and outside the cell. Cell Mol Life Sci. 2011;68(19): 3201-3207.
33. Duner S, Lopatko Lindman J, Ansari D, et al. Pancreatic cancer: the role of pancreatic stellate cells in tumor progression. Pancreatology. 2010;10(6):673-681.
34. Bellail AC, Hunter SB, Brat DJ, et al. Microregional extracellular matrix heterogeneity in brain modulates glioma cell invasion. Int J Biochem Cell Biol. 2004;36(6):1046-1069.
35. Schittenhelm J, Schwab EI, Sperveslage J, et al. Longitudinal expression analysis of alphav integrins in human gliomas reveals upregulation of integrin alphavbeta3 as a negative prognostic factor. J Neuropathol Exp Neurol. 2013;72(3):194-210.
36. Cance WG, Kurenova E, Marlowe T, et al. Disrupting the scaffold to improve focal adhesion kinase-targeted cancer therapeutics. Sci Signal. 2013;6(268):pe10.
37. Lee YJ, Kim IS, Park SA, et al. Periostin-binding DNA aptamer inhibits breast cancer growth and metastasis. Mol Ther. 2013; 21(5):1004-1013.
38. Xu D, Xu H, Ren Y, et al. Cancer stem cell-related gene periostin: a novel prognostic marker for breast cancer. PloS One. 2012;7(10): e46670.
39. Wang Z, Ouyang G. Periostin: a bridge between cancer stem cells and their metastatic niche. Cell Stem Cell. 2012;10(2):111-112.
40. Wang J,Wang C, Meng Q, et al. siRNA targeting Notch-1 decreases glioma stem cell proliferation and tumor growth. Mol Biol Rep. 2012;39(3):2497-2503.
41. Malanchi I, Santamaria-Martinez A, Susanto E, et al. Interactions between cancer stem cells and their niche govern metastatic colonization. Nature. 2012;481(7379):85-89.
42. Tkatchenko TV, Moreno-Rodriguez RA, Conway SJ, et al. Lack of periostin leads to suppression of Notch1 signaling and calcific aortic valve disease. Physiol Genomics. 2009;39(3):160-168.
43. Tanabe H, Takayama I, Nishiyama T, et al. Periostin associates with Notch1 precursor to maintain Notch1 expression under a stress condition in mouse cells. PloS One. 2010;5(8):e12234.
44. Puglisi F, Puppin C, Pegolo E, et al. Expression of periostin in human breast cancer. J Clin Pathol. 2008;61(4):494-498.