Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism

Intensive Care Medicine Experimental

Volumn 3, Issue 1, 2015, Pages 1-11

  Walshe, Criona M ^a   Laffey, John G ^a   Kevin, Leo ^a   O’Toole, Daniel ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Myocardium; Preconditioning; Sepsis

Indexed keywords

ENDOTOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE;

A549 CELL LINE; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CONTROLLED STUDY; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART VENTRICLE PRESSURE; ISCHEMIC PRECONDITIONING; ISOLATED HEART; KIDNEY CELL; LUNG ALVEOLUS EPITHELIUM CELL; MALE; MTT ASSAY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; SEPSIS;

EID: 84986895336     PISSN: None     EISSN: 2197425X     Source Type: Journal    
DOI: 10.1186/s40635-014-0035-9     Document Type: Article

References (47)

1. Dombrovskiy VY, Martin AA, Sunderram J et al (2007) Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 35:1414–1415
2. Mueller-Werdan U, Reithmann C, Werdan K (1996) Cytokines and the heart: molecular mechanisms of septic cardiomyopathy. Springer, Berlin
3. Müller-Werdan U, Werdan K (1999) Septic cardiomyopathy. Curr Opin Crit Care 5:415–421
4. Chao W, Shen Y, Zhu X, Zhao H, Novikov M, Schmidt U, Rosenzweig A (2005) Lipopolysaccharide improves cardiomyocyte survival and function after serum deprivation. J Biol Chem 280(23):21997–22005
5. Fauvel H, Marchetti P, Chopin C, Formstecher P, Nevière R (2001) Differential effects of caspase inhibitors on endotoxin-induced myocardial dysfunction and heart apoptosis. Am J Physiol Heart Circ Physiol 280(4):H1608–H1614
6. McDonald TE, Grinman MN, Carthy CM, Walley KR (2000) Endotoxin infusion in rats induces apoptotic and survival pathways in hearts. Am J Physiol Heart Circ Physiol 179(5):H2053–H2061
7. Hotchkiss RS, Swanson PE, Freeman BD et al (1999) Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction. Crit Care Med 27:1230–1251
8. Rossi MA, Celes MR, Prado CM et al (2007) Myocardial structural changes in long-term human severe sepsis/septic shock may be responsible for cardiac dysfunction. Shock 27:10–18
9. Murry CE, Jennings RB, Reimer K (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischaemic myocardium. Circulation 74(5):1124–1136
10. Greisman SE, Young EJ, Carozza FAJ (1969) Mechanisms of endotoxin tolerance: specificity of the early and late phases of pyrogenic tolerance. J Immunol 103:1223–1236
11. Draisma A, Pickkers P, Bouw MP, van der Hoeven JG (2009) Development of endotoxin tolerance in humans in vivo. Crit Care Med 37(4):1261–1267
12. Zhu X, Zhao H, Graveline AR, Buys ES, Schmidt U, Bloch KD, Rosenzweig A, Chao W (2006) MyD88 and NOS2 are essential for toll-like receptor 4-mediated survival effect in cardiomyocytes. Am J Physiol Heart Circ Physiol 291:H1900–H1909
13. Brown JM, Grosso MA, Terada LS, Whitman GJ, Banerjee A, White CW, Harken AH, Repine JE (1989) Endotoxin pretreatment increases endogenous myocardial catalase activity and decreases ischemia-reperfusion injury of isolated rat hearts. Proc Natl Acad Sci U S A 86:2516–2520
14. Nelson DW, Brown JM, Banerjee A et al (1991) Pretreatment with a nontoxic derivative of endotoxin induces functional protection against cardiac ischemia/reperfusion injury. Surgery 110:365–369
15. Rowland RT, Cleveland JC, Meng X, Ao L, Harken AH, Brown M (1996) A single endotoxin challenge induces delayed myocardial protection against infarcation. J Surg Res 63:193–198
16. Eising GP, Mao L, Schmid-Schonbein GW, Engler RL, Ross J (1996) Effects of induced tolerance to bacterial lipopolysaccharide on myocardial infarct size in rats. Cardiovasc Res 31(1):73–81
17. Lipton BP, Delcarpio JB, McDonough KH (2001) Effects of endotoxin on neutrophil-mediated ischemia/reperfusion injury in the rat heart in vivo. Exp Biol Med (Maywood) 226:320–327
18. McDonough KH, Giaimo ME, Miller HI (1995) Effects of endotoxin on the guinea pig heart response to ischemia reperfusion injury. Shock 4:139–142
19. Song W, Furman BL, Parratt JR (1996) Delayed protection against ischaemia-induced ventricular arrhythmias and infarct size limitation by the prior administration of Escherichia coli endotoxin. Br J Pharmacol 118(8):2157–2163
20. Czura CJ, Tracey KJ (2003) Targeting high mobility group box 1 as a late-acting mediator of inflammation. Crit Care Med 31(1 Suppl):S46–S50
21. Tao W, Deyo DJ, Traber DL et al (2004) Hemodynamic and cardiac contractile function during sepsis caused by cecal ligation and puncture in mice. Shock 21:31–37
22. Wichmann M, W, Haisken JM, Ayala A, Chaudry IH (1996) Melatonin administration following hemorrhagic shock decreases mortality from subsequent septic challenge. J Surg Res 65:109–114
23. Marschall JCC,D (1998) Pre-clinical models of sepsis. Sepsis 2:187–197
24. Chao W (2009) Toll-like receptor signaling: a critical modulator of cell survival and ischemic injury in the heart. Am J Physiol Heart Circ Physiol 196(1):H1–H12
25. Ismail JA, McDonough KH (2002) The role of K-ATP channels in the control of pre-and post-ischemic left ventricular developed pressure in septic rat hearts. Can J Physiol 79:213–219
26. Choi KB, Wong F, Harlan JM, Chaudhary PM, Hood L, Karsan A (1998) Lipopolysaccharide mediates endothelial apoptosis by a FADD-dependent pathway. J Biol Chem 273:20185–20188
27. Hamada E, Nishida T, Uchiyama Y, Nakamura J, Isahara K, Kazuo H, Huang TP, Momoi T, Ito T, Matsuda H (1999) Activation of Kupffer cells and caspase-3 involved in rat hepatocyte apoptosis induced by endotoxin. J Hepatol 30:807–818
28. Goyal A, Wang Y, Graham MM, Doseff AI, Bhatt NY, Marsh CB (2002) Monocyte survival factors induce Akt activation and suppress caspase-3. Am J Respir Cell Mol Biol 26:224–230
29. Ward C, Murray J, Clugston A, Dransfield I, Haslett C, Rossi AG (2005) Interleukin-10 inhibits lipopolysaccharide-induced survival and extracellular signal-regulated kinase activation in human neutrophils. Eur J Immunol 35:2728–2737
30. Lombardo E, Alvarez-Barrientos A, Maroto B, Bosca L, Knaus UG (2007) TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-alpha autocrine signalling. J Immunol 178:3731–3739
31. Lochner A, Marais E, Genade S, Huisamen B, du Toit EF, Moolman JA (2009) Protection of the ischaemic heart: investigations into the phenomenon of ischaemic preconditioning. Cardiovasc J Afr 20(1):43–51
32. Zaugg M, Schaub MC (2003) Signaling and cellular mechanisms in cardiac protection by ischemic and pharmacological preconditioning. J Muscle Res Cell Motil 24:219–249
33. Ip YT, Davis RJ (1998) Signal transduction by the c-Jun N-terminal kinase (JNK): from inflammation to development. Curr Opin Cell Biol 10:205–219
34. Robinson MJ, Cobb MH (1997) Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 9:180–186
35. Cowley S, Paterson H, Kemp P, Marchall CJ (1994) Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells. Cell Mol Life Sci 77:841–852
36. Leppa S, Saffrich R, Ansorge W, Bohmann D (1998) Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation. EMBO J 17:4404–4413
37. Mansour SJ, Matten WT, Herman AS, Candia JM, Rong S, Fukasawa K, Vande Woude GF, Ahn NG (1994) Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265:966–970
38. Lotze MT, Tracey KJ (2005) High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat Rev Immunol 5(4):331–342
39. Roulston A, Reinhard C, Amiri P, Williams LT (1998) Early activation of c-Jun N-terminal kinase and p38 kinase regulates cell survival in response to tumor necrosis factor-α. J Biol Chem 273:10232
40. Schwenger P, Bellosta P, Vietor I, Basilico C, Skolnik EY, Vilcek J (1997) Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation. Proc Natl Acad Sci U S A 94:2869
41. Xuan YT, Tang XL, Banerjee S, Takano H, Li RC, Han H, Qiu Y, Li JJ, Bolli R (1999) Nuclear factor-kappaB plays an essential role in the late phase of ischemic preconditioning in conscious rabbits. Circ Res 84(9):1095–1109
42. Yang RC, Chen HW, Lu TS, Hsu C (2000) Potential protective effect of NF-kappaB activity on the polymicrobial sepsis of rats preconditioning heat shock treatment. Clin Chim Acta 302(1–2):11–22
43. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ (1999) HMG-1 as a late mediator of endotoxin lethality in mice. Science 285(5425):248–251
44. Wang H, Yang H, Tracey KJ (2004) Extracellular role of HMGB1 in inflammation and sepsis. J Intern Med 255:320–331
45. Wang H, Liao H, Ochani M, Justiniani M, Lin X, Yang L, Al Abed Y, Wang H, Metz C, Miller EJ et al (2004) Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis. Nat Med 10:1216–1221
46. Yang H (2004) Reversing established sepsis with antagonists of endogenous high-mobility group box 1. Proc Natl Acad Sci U S A 101:296–301
47. Oozawa S, Mori S, Kanke T, Takahashi H, Liu K, Tomono Y, Asanuma M, Miyazaki I, Nishibori M, Sano S (2008) Effects of HMGB1 on ischemia-reperfusion injury in the rat heart. Circ J 72(7):1178–1184