MiR?221 targets HMGA2 to inhibit bleomycin induced pulmonary fibrosis by regulating TGF1/Smad3-induced EMT

International Journal of Molecular Medicine

Volumn 38, Issue 4, 2016, Pages 1208-1216

  Wang, Yi Chun ^a,b   Liu, Jing Shi ^b   Tang, Hao Ke ^c   Nie, Jing ^b   Zhu, Ji Xian ^b   Wen, Ling Ling ^b   Guo, Qu Lian ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Departments of Critical Care Medicine   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Bleomycin induced pulmonary fibrosis; Epithelial mesenchymal transition; High mobility group AT hook 2; MicroRNA?221; Transforming growth factor1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; EOSIN; HEMATOXYLIN; HIGH MOBILITY GROUP A2 PROTEIN; MICRORNA 221; NERVE CELL ADHESION MOLECULE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN; BLEOMYCIN; MICRORNA; MIRN221 MICRORNA, HUMAN; MIRN221 MICRORNA, MOUSE;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FIBROSING ALVEOLITIS; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HMGA2 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LUCIFERASE ASSAY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS WALL; LUNG FIBROSIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; A-549 CELL LINE; ANIMAL; BRONCHUS; DISEASE MODEL; EPITHELIUM CELL; GENETICS; METABOLISM; PATHOLOGY;

A549 CELLS; ANIMALS; BLEOMYCIN; BRONCHI; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOWN-REGULATION; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; HMGA2 PROTEIN; HUMANS; IDIOPATHIC PULMONARY FIBROSIS; MICE; MICRORNAS; SIGNAL TRANSDUCTION; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION;

EID: 84986893049     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2016.2705     Document Type: Article

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