Beta-adrenergic antagonists in the prevention of gastrointestinal rebleeding in patients with cirrhosis: A meta-analysis

Hepatology

Volumn 25, Issue 1, 1997, Pages 63-70

  Bernard, Brigitte ^a   Lebrec, Didier ^b   Mathurin, Philippe ^a   Opolon, Pierre ^a   Poynard, Thierry ^a,c  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b BEAUJON HOSPITAL   (France)

^c CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; NADOLOL; PLACEBO; PROPRANOLOL;

ARTICLE; ASTHMA; BRADYCARDIA; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; ESOPHAGUS VARICES BLEEDING; GASTROINTESTINAL HEMORRHAGE; HEART FAILURE; HUMAN; LIVER CIRRHOSIS; META ANALYSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURVIVAL TIME; TREATMENT OUTCOME;

EID: 0031030010     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.510250112     Document Type: Article

References (37)

1. Lebrec D, Nouel O, Corbic M, Benhamou JP. Propranolol - a medical treatment for portal hypertension? Lancet 1980;2:180-182.
2. Lebrec D, Poynard T, Hillon P, Benhamou JP. Propranolol for prevention or recurrent gastrointestinal bleeding in patients with cirrhosis. N Engl J Med 1981;305:1371-1374.
3. Burroughs AK, Jenkins WJ, Sherlock S, Dunk A, Walt RP, Osuafor OK, Mackie S, et al. Controlled trial of propranolol for the prevention of recurrent variceal hemorrhage in patients with cirrhosis. N Engl J Med 1983; 25:1539-1542.
4. Villeneuve JP, Pomier-Layrargues G, Infante-Rivard C, Willems B, Huet PM, Marleau D, Viallet A. Propranolol for the prevention of recurrent variceal hemorrhage: a controlled trial. HEPATOLOGY 1986;6:1239-1243.
5. Cerbelaud P, Lavignolle A, Perrin D, Jutel P, Beaujard E, Colomb P, Le Bodic L. Propranolol et prévention des récidives de rupture de varice oesophagienne du cirrhotique [Abstract]. Gastroentérol Clin Biol 1986;18: A10.
6. Queuniet AM, Czernichow P, Lerebours E, Ducrotte P, Tranvouez JL, Colin R. Etude contrôlée du propranolol dans la prévention des récidives hémorragiques chez les patients cirrhotiques. Gastroentérol Clin Biol 1987;11:41-47.
7. Gatta A, Merkel C, Sacerdoti D, Bolognesi M, Caregaro L, Zuin R, Angeli P, et al. Nadolol for prevention of variceal rebleeding in cirrhosis: a controlled clinical trial. Digestion 1987;37:22-28.
8. Kobe E, Schentke KU. Unsichere Rezidivprophylaxe von Ösophagusvarizenblutungen durch Propranolol bei Leberzirrhotikern: eine prospektive kontrollierte Studie. Z Klin Med 1987;42:507-510.
9. Colombo M, De Franchis R, Tommasini M, Sangiovanni A, Dioguardi N. β-blockade prevents recurrent gastrointestinal bleeding in well-compensated patients with alcoholic cirrhosis: a multicenter randomized controlled trial. HEPATOLOGY 1989;9:433-438.
10. Sheen IS, Chen TY, Liaw YF. Randomized controlled study of propranolol for prevention of recurrent esophageal varices bleeding in patients with cirrhosis. Liver 1989;9:1-5.
11. Colman J, Jones P, Finch C, Dudley F. Propranolol in the prevention of variceal hemorrhage in alcoholic cirrhotic patients [Abstract]. HEPATOLOGY 1990;12:851.
12. Garden OJ, Mills PR, Birnie GG, Murray GD, Carter DC. Propranolol in the prevention of recurrent variceal hemorrhage in cirrhotic patients. Gastroenterology 1990;98:185-190.
13. Rossi V, Calès P, Burtin P, Charneau J, Person B, Pujol P, Valentin S, et al. Prevention of recurrent variceal bleeding in alcoholic cirrhotic patients: prospective controlled trial of propranolol and sclerotherapy. J Hepatol 1991;12:283-289.
14. Kiire CF. Controlled trial of propranolol to prevent recurrent variceal bleeding in patients with non-cirrhotic portal fibrosis. Br Med J 1989;298: 1363-1365.
15. Pérez-Ayuso RM, Piqué JM, Bosch J, Panés J, Gonzalez A, Pérez R, Rigau J, et al. Propranolol in prevention of recurrent bleeding from severe portal hypertensive gastropathy in cirrhosis. Lancet 1991;337:1431-1434.
16. Pignon JP, Poynard T, Naveau S, Chaput JC. Méta-analyse des essais randomisés des β-bloquants dans la prévention des hémorragies digestives des sujets atteints de cirrhose [Abstract]. Gastroentérol Clin Biol 1988; 12:A175.
17. Pagliaro L, Burroughs AK, Sorensen TIA, Lebrec D, Morabito A, D'Amico G, Tiné F. Therapeutic controversies and randomized controlled trials (RCTs): prevention of bleeding and rebleeding in cirrhosis. Gastroenterol Int 1989;2:71-84.
18. Poynard T. β-blockers should be used to prevent variceal bleeding? In: Gitnick G, ed. Debates in Medicine. Vol 2. New York: Year Book Medical Publisher, Inc, 1989:76-83.
19. Hayes PC, Davis JM, Lewis JA, Bouchier IAD. Meta-analysis of value of propranolol in prevention of variceal haemorrhage. Lancet 1990;336:153-156.
20. Pagliaro L, Burroughs AK, Sorensen TIA, Lebrec D, Morabito A, D'Amico GD, Tine F. Beta-blockers for preventing variceal bleeding. Lancet 1990; 336:1001-1002.
21. Burroughs AK, McCormick PA. Prevention of variceal bleeding. Gastroenterol Clin North Am 1992;21:119-147.
22. D'Amico G, Pagliaro L, Bosch J. The treatment of portal hypertension: a meta-analytic review. HEPATOLOGY 1995;22:332-354.
23. Sacks HS, Berrier J, Reitman D, Ancona-Berk VA, Chalmers TC. Metaanalyses of randomized controlled trials. N Engl J Med 1987;316:450-455.
24. Poynard T, Conn HO. The retrieval of randomized clinical trials in liver disease from the medical literature: a comparison of MEDLARS and manual methods. Controlled Clin Trials 1985;6:271-279.
25. Pugh RNH, Murray-Lyon M, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg 1973; 60:646-649.
26. Yusuf S, Peto R, Lewis J, Collins R, Sleight P. Beta-blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 1985;27:335-371.
27. Der Simonian R, Laird N. Meta-analysis in clinical trials. Controlled Clin Trials 1986;7:177-188.
28. Poynard T. Evaluation de la qualité des essais thérapeutiques randomisés. Presse Med 1988;17:315-318.
29. Bützow GH, Remmecke J, Bräuer A. Metoprolol in portal hypertension. Klin Wochenschr 1982;60:1311-1314.
30. Uribe M, Ballesteros A, Strauss R, Rosales J, Guevara L. Use of cardioselective beta-blockers in portal hypertension and advanced liver disease [Abstract]. Gastroenterology 1983;2:1339A.
31. Pasta L, Pagliaro L, Simonetti RG, Maringhini A, Marceno MP, D'Amico G. Propranolol for prevention of upper GI rebleeding in cirrhosis. Ital J Gastroenterol 1985;17:136-138.
32. Lopez Fuerte F, Cardenas Rojas JA, Esquivel Lopez A, Perches Vega A. Prevencion de la hemorragia por varices esofagicas en pacientas con cirrosis hepatica mediante la administracion de propranolol. Rev Gastroenterol Mex 1986;51:187-190.
33. Hosking SW, Kennedy HJ, Seddon I, Triger DR. The role of propranolol in congestive gastropathy of portal hypertension. HEPATOLOGY 1987;7: 437-441.
34. Marbet UA, Straumann A, Gyr KE, Beglinger C, Schaub N, Vögtlin J, Loosli J, et al. Reduction in early recurrence of variceal bleeding by propranolol. Scand J Gastroenterol 1988;23:369-374.
35. Qureshi H, Zuberi SJ, Alam E. Efficacy of oral propranolol and injection sclerotherapy in the long-term management of variceal bleeding. Digestion 1990;46:193-198.
36. Poynard T, Calès P, Pasta L, Ideo G, Pascal JP, Pagliaro L, Lebrec D, et al. Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. N Engl J Med 1991;324:1532-1538.
37. Laine L, Cook D. Endoscopic ligation compared with sclerotherapy for treatment of esophageal variceal bleeding. Ann Intern Med 1995;123:280-287.