Increased levels of the acetaldehyde-derived DNA adduct N2-ethyldeoxyguanosine in oral mucosa DNA from Rhesus monkeys exposed to alcohol

Mutagenesis

Volumn 31, Issue 5, 2016, Pages 553-558

  Balbo, Silvia ^a   Juanes, Rita Cervera ^b   Khariwala, Samir ^a   Baker, Erich J ^c   Daunais, James B ^d   Grant, Kathleen A ^b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c Baylor University   (United States)

^d WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; ALCOHOL; DEOXYGUANOSINE DERIVATIVE; DNA; N 2 ETHYLDEOXYGUANOSINE; UNCLASSIFIED DRUG; DEOXYGUANOSINE; DNA ADDUCT; N(2)-ETHYLDEOXYGUANOSINE;

ADULT; ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; ELECTROSPRAY; ESOPHAGUS; FEMALE; LIQUID CHROMATOGRAPHY; MALE; MAMMARY GLAND; MOUTH MUCOSA; NONHUMAN; PRIORITY JOURNAL; RHESUS MONKEY; TANDEM MASS SPECTROMETRY; ADVERSE EFFECTS; ANALOGS AND DERIVATIVES; ANALYSIS; ANIMAL; CHEMISTRY; DRINKING BEHAVIOR; DRUG EFFECTS; ESOPHAGUS MUCOSA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; UDDER;

ACETALDEHYDE; ALCOHOL DRINKING; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYGUANOSINE; DNA ADDUCTS; DNA DAMAGE; ESOPHAGEAL MUCOSA; FEMALE; MACACA MULATTA; MALE; MAMMARY GLANDS, ANIMAL; MOUTH MUCOSA; TANDEM MASS SPECTROMETRY;

EID: 84986003577     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gew016     Document Type: Article

References (23)

1. IARC working group on the evaluation of carcinogenic risks to humans (2010) Alcohol consuption and ethyl carbamate. IARC Monogr Eval. Carcinog. Risks Hum., 96, 171-602.
2. Baan, R., Straif, K., Grosse, Y., Secretan, B., El Ghissassi, F., Bouvard, V., Altieri, A., and Cogliano, V. (2007) Carcinogenicity of alcoholic beverages. Lancet Oncol., 8, 292-293.
3. Seitz, H. K., and Mueller, S. (2010) Mechanisms of tumorgenesis associated with alcohol consumption. Alcohol. Clin. Exp. Res., 34, 47A.
4. Yokoyama, A., Tsutsumi, E., Imazeki, H., Suwa, Y., Nakamura, C., Mizukami, T., and Yokoyama, T. (2008) Salivary acetaldehyde concentration according to alcoholic beverage consumed and aldehyde dehydrogenase-2 genotype. Alcohol. Clin. Exp. Res., 32, 1607-1614.
5. Lachenmeier, D. W., and Monakhova, Y. B. (2011) Short-Term salivary acetaldehyde increase due to direct exposure to alcoholic beverages as an additional cancer risk factor beyond ethanol metabolism. J. Exp. Clin. Cancer Res., 30, 3.
6. Jokelainen, K., Heikkonen, E., Roine, R., Lehtonen, H., and Salaspuro, M. (1996) Increased acetaldehyde production by mouthwashings from patients with oral cavity, laryngeal, or pharyngeal cancer. Alcohol. Clin. Exp. Res., 20, 1206-1210.
7. Kurkivuori, J., Salaspuro, V., Kaihovaara, P., Kari, K., Rautemaa, R., Grönroos, L., Meurman, J. H., and Salaspuro, M. (2007) Acetaldehyde production from ethanol by oral streptococci. Oral Oncol., 43, 181-186.
8. Brooks, P. J., and Theruvathu, J. A. (2005) DNA adducts from acetaldehyde: implications for alcohol-related carcinogenesis. Alcohol, 35, 187-193.
9. Balbo, S., Meng, L., Bliss, R. L., Jensen, J. A., Hatsukami, D. K., and Hecht, S. S. (2012) Kinetics of DNA adduct formation in the oral cavity after drinking alcohol. Cancer Epidemiol. Biomarkers Prev., 21, 601-608.
10. Daunais, J. B., Davenport, A. T., Helms, C. M., Gonzales, S. W., Hemby, S. E., Friedman, D. P., Farro, J. P., Baker, E. J., and Grant, K. A. (2014) Monkey alcohol tissue research resource: banking tissues for alcohol research. Alcohol. Clin. Exp. Res., 38, 1973-1981.
11. Grant, K. A., Leng, X., Green, H. L., Szeliga, K. T., Rogers, L. S., and Gonzales, S. W. (2008) Drinking typography established by scheduled induction predicts chronic heavy drinking in a monkey model of ethanol selfadministration. Alcohol. Clin. Exp. Res., 32, 1824-1838.
12. Baker, E. J., Farro, J., Gonzales, S., Helms, C., and Grant, K. A. (2014) Chronic alcohol self-Administration in monkeys shows long-Term quantity/frequency categorical stability. Alcohol. Clin. Exp. Res., 38, 2835-2843.
13. Davenport, A. T., Grant, K. A., Szeliga, K. T., Friedman, D. P., and Daunais, J. B. (2014) Standardized method for the harvest of nonhuman primate tissue optimized for multiple modes of analyses. Cell Tissue Bank., 15, 99-110.
14. Wang, M., Yu, N., Chen, L., Villalta, P. W., Hochalter, J. B., and Hecht, S. S. (2006) Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosine. Chem. Res. Toxicol., 19, 319-324.
15. Zhao, L., Balbo, S., Wang, M., Upadhyaya, P., Khariwala, S. S., Villalta, P. W., and Hecht, S. S. (2013) Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with ®-or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study. Chem. Res. Toxicol., 26, 1526-1535.
16. Zhang, S., Villalta, P. W., Wang, M., and Hecht, S. S. (2006) Analysis of crotonaldehyde-And acetaldehyde-derived 1, n(2)-propanodeoxyguanosine adducts in DNA from human tissues using liquid chromatography electrospray ionization tandem mass spectrometry. Chem. Res. Toxicol., 19, 1386-1392.
17. Gunzerath, L., Faden, V., Zakhari, S., and Warren, K. (2004) National Institute on Alcohol Abuse and Alcoholism report on moderate drinking. Alcohol. Clin. Exp. Res., 28, 829-847.
18. Liu, Y., Chen, H., Sun, Z., and Chen, X. (2015) Molecular mechanisms of ethanol-Associated oro-esophageal squamous cell carcinoma. Cancer Lett., 361, 164-173.
19. Yu, H. S., Oyama, T., Matsuda, T., Isse, T., Yamaguchi, T., Tanaka, M., Tsuji, M., and Kawamoto, T. (2012) The effect of ethanol on the formation of N2-ethylidene-dG adducts in mice: implications for alcoholrelated carcinogenicity of the oral cavity and esophagus. Biomarkers, 17, 269-274.
20. Weinberg, M. A., and Bral, M. (1999) Laboratory animal models in periodontology. J. Clin. Periodontol., 26, 335-340.
21. Seitz, H. K., Pelucchi, C., Bagnardi, V., and La Vecchia, C. (2012) Epidemiology and pathophysiology of alcohol and breast cancer: Update 2012. Alcohol Alcohol, 47, 204-212.
22. Fanelli, S. L., Maciel, M. E., Díaz Gómez, M. I., Delgado de Layño, A. M., Bietto, F. M., Castro, J. A., and Castro, G. D. (2011) Further studies on the potential contribution of acetaldehyde accumulation and oxidative stress in rat mammary tissue in the alcohol drinking promotion of breast cancer. J. Appl. Toxicol., 31, 11-19.
23. Jones, A. W., and Andersson, L. (2003) Comparison of ethanol concentrations in venous blood and end-expired breath during a controlled drinking study. Forensic Sci. Int., 132, 18-25.