메뉴 건너뛰기




Volumn 335, Issue , 2016, Pages 103-113

Sex-dependent mitophagy and neuronal death following rat neonatal hypoxia–ischemia

Author keywords

cell death; lysosome; mitochondria; mitophagy; morphology; sex dependent

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MITOCHONDRIAL PROTEIN; TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20;

EID: 84985996031     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2016.08.026     Document Type: Article
Times cited : (58)

References (55)
  • 1
    • 84955476112 scopus 로고    scopus 로고
    • Mechanisms of neurodegeneration after severe hypoxic-ischemic injury in the neonatal rat brain
    • Askalan, R., Gabarin, N., Armstrong, E.A., Fang, L.Y., Couchman, D., Yager, J.Y., Mechanisms of neurodegeneration after severe hypoxic-ischemic injury in the neonatal rat brain. Brain Res 1629 (2015), 94–103.
    • (2015) Brain Res , vol.1629 , pp. 94-103
    • Askalan, R.1    Gabarin, N.2    Armstrong, E.A.3    Fang, L.Y.4    Couchman, D.5    Yager, J.Y.6
  • 2
    • 84936097947 scopus 로고    scopus 로고
    • Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro
    • Au, A.K., Chen, Y., Du, L., Smith, C.M., Manole, M.D., Baltagi, S.A., Chu, C.T., Aneja, R.K., Bayir, H., Kochanek, P.M., Clark, R.S., Ischemia-induced autophagy contributes to neurodegeneration in cerebellar Purkinje cells in the developing rat brain and in primary cortical neurons in vitro. Biochim Biophys Acta 1852 (2015), 1902–1911.
    • (2015) Biochim Biophys Acta , vol.1852 , pp. 1902-1911
    • Au, A.K.1    Chen, Y.2    Du, L.3    Smith, C.M.4    Manole, M.D.5    Baltagi, S.A.6    Chu, C.T.7    Aneja, R.K.8    Bayir, H.9    Kochanek, P.M.10    Clark, R.S.11
  • 3
    • 84905398294 scopus 로고    scopus 로고
    • Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage
    • Baek, S.H., Noh, A.R., Kim, K.A., Akram, M., Shin, Y.J., Kim, E.S., Yu, S.W., Majid, A., Bae, O.N., Modulation of mitochondrial function and autophagy mediates carnosine neuroprotection against ischemic brain damage. Stroke 45 (2014), 2438–2443.
    • (2014) Stroke , vol.45 , pp. 2438-2443
    • Baek, S.H.1    Noh, A.R.2    Kim, K.A.3    Akram, M.4    Shin, Y.J.5    Kim, E.S.6    Yu, S.W.7    Majid, A.8    Bae, O.N.9
  • 4
    • 31344439662 scopus 로고    scopus 로고
    • Free radicals, mitochondria, and hypoxia-ischemia in the developing brain
    • Blomgren, K., Hagberg, H., Free radicals, mitochondria, and hypoxia-ischemia in the developing brain. Free Radical Biol Med 40 (2006), 388–397.
    • (2006) Free Radical Biol Med , vol.40 , pp. 388-397
    • Blomgren, K.1    Hagberg, H.2
  • 5
    • 84856457651 scopus 로고    scopus 로고
    • Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation
    • Carloni, S., Buonocore, G., Longini, M., Proietti, F., Balduini, W., Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation. Neuroscience 203 (2012), 160–169.
    • (2012) Neuroscience , vol.203 , pp. 160-169
    • Carloni, S.1    Buonocore, G.2    Longini, M.3    Proietti, F.4    Balduini, W.5
  • 6
    • 84899056512 scopus 로고    scopus 로고
    • Sex differences in behavioral outcome following neonatal hypoxia ischemia: Insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic injury
    • Cohen, S.S., Stonestreet, B.S., Sex differences in behavioral outcome following neonatal hypoxia ischemia: Insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic injury. Exp Neurol 256 (2014), 70–73.
    • (2014) Exp Neurol , vol.256 , pp. 70-73
    • Cohen, S.S.1    Stonestreet, B.S.2
  • 7
    • 84944724631 scopus 로고    scopus 로고
    • Therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy – Where to from here?
    • Davidson, J.O., Wassink, G., van den Heuij, L.G., Bennet, L., Gunn, A.J., Therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy – Where to from here?. Front Neurol, 6, 2015, 198.
    • (2015) Front Neurol , vol.6 , pp. 198
    • Davidson, J.O.1    Wassink, G.2    van den Heuij, L.G.3    Bennet, L.4    Gunn, A.J.5
  • 8
    • 84925543833 scopus 로고    scopus 로고
    • Sex differences in mitochondrial (dys)function: implications for neuroprotection
    • Demarest, T.G., McCarthy, M.M., Sex differences in mitochondrial (dys)function: implications for neuroprotection. J Bioenerg Biomembr 47 (2015), 173–188.
    • (2015) J Bioenerg Biomembr , vol.47 , pp. 173-188
    • Demarest, T.G.1    McCarthy, M.M.2
  • 9
    • 84966400933 scopus 로고    scopus 로고
    • Sex-dependent mitochondrial respiratory impairment and oxidative stress in a rat model of neonatal hypoxic-ischemic encephalopathy
    • Demarest, T.G., Schuh, R.A., Waddell, J., McKenna, M.C., Fiskum, G., Sex-dependent mitochondrial respiratory impairment and oxidative stress in a rat model of neonatal hypoxic-ischemic encephalopathy. J Neurochem 137 (2016), 714–729.
    • (2016) J Neurochem , vol.137 , pp. 714-729
    • Demarest, T.G.1    Schuh, R.A.2    Waddell, J.3    McKenna, M.C.4    Fiskum, G.5
  • 10
    • 4644305774 scopus 로고    scopus 로고
    • Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway
    • Du, L., Bayir, H., Lai, Y., Zhang, X., Kochanek, P.M., Watkins, S.C., Graham, S.H., Clark, R.S., Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem 279 (2004), 38563–38570.
    • (2004) J Biol Chem , vol.279 , pp. 38563-38570
    • Du, L.1    Bayir, H.2    Lai, Y.3    Zhang, X.4    Kochanek, P.M.5    Watkins, S.C.6    Graham, S.H.7    Clark, R.S.8
  • 12
    • 84872090675 scopus 로고    scopus 로고
    • Hypothermia and erythropoietin for neuroprotection after neonatal brain damage
    • Fan, X., van, B.F., van der Kooij, M.A., Heijnen, C.J., Groenendaal, F., Hypothermia and erythropoietin for neuroprotection after neonatal brain damage. Pediatr Res 73 (2013), 18–23.
    • (2013) Pediatr Res , vol.73 , pp. 18-23
    • Fan, X.1    van, B.F.2    van der Kooij, M.A.3    Heijnen, C.J.4    Groenendaal, F.5
  • 14
    • 84959462043 scopus 로고    scopus 로고
    • Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury
    • He, G., Xu, W., Tong, L., Li, S., Su, S., Tan, X., Li, C., Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury. Apoptosis 21 (2016), 390–403.
    • (2016) Apoptosis , vol.21 , pp. 390-403
    • He, G.1    Xu, W.2    Tong, L.3    Li, S.4    Su, S.5    Tan, X.6    Li, C.7
  • 15
    • 84866170598 scopus 로고    scopus 로고
    • Sex differences in mechanisms and outcome of neonatal hypoxia-ischemia in rodent models: implications for sex-specific neuroprotection in clinical neonatal practice
    • Hill, C.A., Fitch, R.H., Sex differences in mechanisms and outcome of neonatal hypoxia-ischemia in rodent models: implications for sex-specific neuroprotection in clinical neonatal practice. Neurol Res Int, 2012, 2012, 867531.
    • (2012) Neurol Res Int , vol.2012 , pp. 867531
    • Hill, C.A.1    Fitch, R.H.2
  • 16
    • 84859103053 scopus 로고    scopus 로고
    • Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats
    • Hill, C.A., Alexander, M.L., McCullough, L.D., Fitch, R.H., Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats. Dev Neurosci 33 (2011), 494–504.
    • (2011) Dev Neurosci , vol.33 , pp. 494-504
    • Hill, C.A.1    Alexander, M.L.2    McCullough, L.D.3    Fitch, R.H.4
  • 17
    • 84859103053 scopus 로고    scopus 로고
    • Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats
    • Hill, C.A., Alexander, M.L., McCullough, L.D., Fitch, R.H., Inhibition of X-linked inhibitor of apoptosis with embelin differentially affects male versus female behavioral outcome following neonatal hypoxia-ischemia in rats. Dev Neurosci 33 (2011), 494–504.
    • (2011) Dev Neurosci , vol.33 , pp. 494-504
    • Hill, C.A.1    Alexander, M.L.2    McCullough, L.D.3    Fitch, R.H.4
  • 18
    • 84938270248 scopus 로고    scopus 로고
    • Ischemic preconditioning provides neuroprotection by induction of AMP-activated protein kinase-dependent autophagy in a rat model of ischemic stroke
    • Jiang, T., Yu, J.T., Zhu, X.C., Zhang, Q.Q., Tan, M.S., Cao, L., Wang, H.F., Shi, J.Q., Gao, L., Qin, H., Zhang, Y.D., Tan, L., Ischemic preconditioning provides neuroprotection by induction of AMP-activated protein kinase-dependent autophagy in a rat model of ischemic stroke. Mol Neurobiol 51 (2015), 220–229.
    • (2015) Mol Neurobiol , vol.51 , pp. 220-229
    • Jiang, T.1    Yu, J.T.2    Zhu, X.C.3    Zhang, Q.Q.4    Tan, M.S.5    Cao, L.6    Wang, H.F.7    Shi, J.Q.8    Gao, L.9    Qin, H.10    Zhang, Y.D.11    Tan, L.12
  • 19
    • 78650824047 scopus 로고    scopus 로고
    • Developmental time course of estradiol, testosterone, and dihydrotestosterone levels in discreteregions of male and female rat brain
    • Konkle, A.T., McCarthy, M.M., Developmental time course of estradiol, testosterone, and dihydrotestosterone levels in discreteregions of male and female rat brain. Endocrinology 152 (2011), 223–235.
    • (2011) Endocrinology , vol.152 , pp. 223-235
    • Konkle, A.T.1    McCarthy, M.M.2
  • 20
    • 77954315863 scopus 로고    scopus 로고
    • Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy
    • Kurinczuk, J.J., White-Koning, M., Badawi, N., Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy. Early Hum Dev 86 (2010), 329–338.
    • (2010) Early Hum Dev , vol.86 , pp. 329-338
    • Kurinczuk, J.J.1    White-Koning, M.2    Badawi, N.3
  • 22
    • 84931958134 scopus 로고    scopus 로고
    • ROS and autophagy: interactions and molecular regulatory mechanisms
    • Li, L., Tan, J., Miao, Y., Lei, P., Zhang, Q., ROS and autophagy: interactions and molecular regulatory mechanisms. Cell Mol Neurobiol 35 (2015), 615–621.
    • (2015) Cell Mol Neurobiol , vol.35 , pp. 615-621
    • Li, L.1    Tan, J.2    Miao, Y.3    Lei, P.4    Zhang, Q.5
  • 23
    • 84949563130 scopus 로고    scopus 로고
    • Helium preconditioning protects against neonatal hypoxia-ischemia via nitric oxide mediated up-regulation of antioxidases in a rat model
    • Li, Y., Liu, K., Kang, Z.M., Sun, X.J., Liu, W.W., Mao, Y.F., Helium preconditioning protects against neonatal hypoxia-ischemia via nitric oxide mediated up-regulation of antioxidases in a rat model. Behav Brain Res 300 (2016), 31–37.
    • (2016) Behav Brain Res , vol.300 , pp. 31-37
    • Li, Y.1    Liu, K.2    Kang, Z.M.3    Sun, X.J.4    Liu, W.W.5    Mao, Y.F.6
  • 24
    • 65549170958 scopus 로고    scopus 로고
    • Sex differences in caspase activation after stroke
    • Liu, F., Li, Z., Li, J., Siegel, C., Yuan, R., McCullough, L.D., Sex differences in caspase activation after stroke. Stroke 40 (2009), 1842–1848.
    • (2009) Stroke , vol.40 , pp. 1842-1848
    • Liu, F.1    Li, Z.2    Li, J.3    Siegel, C.4    Yuan, R.5    McCullough, L.D.6
  • 25
    • 79954792489 scopus 로고    scopus 로고
    • Sex differences in the response to poly(ADP-ribose) polymerase-1 deletion and caspase inhibition after stroke
    • Liu, F., Lang, J., Li, J., Benashski, S.E., Siegel, M., Xu, Y., McCullough, L.D., Sex differences in the response to poly(ADP-ribose) polymerase-1 deletion and caspase inhibition after stroke. Stroke 42 (2011), 1090–1096.
    • (2011) Stroke , vol.42 , pp. 1090-1096
    • Liu, F.1    Lang, J.2    Li, J.3    Benashski, S.E.4    Siegel, M.5    Xu, Y.6    McCullough, L.D.7
  • 26
    • 79957552463 scopus 로고    scopus 로고
    • Sexual dimorphism in ischemic stroke: lessons from the laboratory
    • Manwani, B., McCullough, L.D., Sexual dimorphism in ischemic stroke: lessons from the laboratory. Womens Health (Lond Engl) 7 (2011), 319–339.
    • (2011) Womens Health (Lond Engl) , vol.7 , pp. 319-339
    • Manwani, B.1    McCullough, L.D.2
  • 27
    • 84928748780 scopus 로고    scopus 로고
    • Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy
    • Mirza, M.A., Ritzel, R., Xu, Y., McCullough, L.D., Liu, F., Sexually dimorphic outcomes and inflammatory responses in hypoxic-ischemic encephalopathy. J Neuroinflamm, 12, 2015, 32.
    • (2015) J Neuroinflamm , vol.12 , pp. 32
    • Mirza, M.A.1    Ritzel, R.2    Xu, Y.3    McCullough, L.D.4    Liu, F.5
  • 28
    • 84857508603 scopus 로고    scopus 로고
    • The oxygen free radicals originating from mitochondrial complex I contribute to oxidative brain injury following hypoxia-ischemia in neonatal mice
    • Niatsetskaya, Z.V., Sosunov, S.A., Matsiukevich, D., Utkina-Sosunova, I.V., Ratner, V.I., Starkov, A.A., Ten, V.S., The oxygen free radicals originating from mitochondrial complex I contribute to oxidative brain injury following hypoxia-ischemia in neonatal mice. J Neurosci 32 (2012), 3235–3244.
    • (2012) J Neurosci , vol.32 , pp. 3235-3244
    • Niatsetskaya, Z.V.1    Sosunov, S.A.2    Matsiukevich, D.3    Utkina-Sosunova, I.V.4    Ratner, V.I.5    Starkov, A.A.6    Ten, V.S.7
  • 29
    • 33846441658 scopus 로고    scopus 로고
    • Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway
    • Nijboer, C.H., Groenendaal, F., Kavelaars, A., Hagberg, H.H., van, B.F., Heijnen, C.J., Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway. J Cereb Blood Flow Metab 27 (2007), 282–292.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 282-292
    • Nijboer, C.H.1    Groenendaal, F.2    Kavelaars, A.3    Hagberg, H.H.4    van, B.F.5    Heijnen, C.J.6
  • 30
    • 36248945038 scopus 로고    scopus 로고
    • Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as “continuum” phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain
    • Northington, F.J., Zelaya, M.E., O'Riordan, D.P., Blomgren, K., Flock, D.L., Hagberg, H., Ferriero, D.M., Martin, L.J., Failure to complete apoptosis following neonatal hypoxia-ischemia manifests as “continuum” phenotype of cell death and occurs with multiple manifestations of mitochondrial dysfunction in rodent forebrain. Neuroscience 149 (2007), 822–833.
    • (2007) Neuroscience , vol.149 , pp. 822-833
    • Northington, F.J.1    Zelaya, M.E.2    O'Riordan, D.P.3    Blomgren, K.4    Flock, D.L.5    Hagberg, H.6    Ferriero, D.M.7    Martin, L.J.8
  • 32
    • 41149164082 scopus 로고    scopus 로고
    • Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus
    • Nunez, J.L., McCarthy, M.M., Androgens predispose males to GABAA-mediated excitotoxicity in the developing hippocampus. Exp Neurol 210 (2008), 699–708.
    • (2008) Exp Neurol , vol.210 , pp. 699-708
    • Nunez, J.L.1    McCarthy, M.M.2
  • 33
    • 84925539116 scopus 로고    scopus 로고
    • Mitochondrial dynamics: cell-type and hippocampal region specific changes following global cerebral ischemia
    • Owens, K., Park, J.H., Gourley, S., Jones, H., Kristian, T., Mitochondrial dynamics: cell-type and hippocampal region specific changes following global cerebral ischemia. J Bioenerg Biomembr 47 (2015), 13–31.
    • (2015) J Bioenerg Biomembr , vol.47 , pp. 13-31
    • Owens, K.1    Park, J.H.2    Gourley, S.3    Jones, H.4    Kristian, T.5
  • 34
    • 84899887277 scopus 로고    scopus 로고
    • Drp1 in ischemic neuronal death: an unusual suspect
    • Pradeep, H., Sharma, B., Rajanikant, G.K., Drp1 in ischemic neuronal death: an unusual suspect. Curr Med Chem 21 (2014), 2183–2189.
    • (2014) Curr Med Chem , vol.21 , pp. 2183-2189
    • Pradeep, H.1    Sharma, B.2    Rajanikant, G.K.3
  • 35
    • 84939883006 scopus 로고    scopus 로고
    • AKT-related autophagy contributes to the neuroprotective efficacy of hydroxysafflor yellow A against ischemic stroke in rats
    • Qi, Z., Yan, F., Shi, W., Zhang, C., Dong, W., Zhao, Y., Shen, J., Ji, X., Liu, K.J., Luo, Y., AKT-related autophagy contributes to the neuroprotective efficacy of hydroxysafflor yellow A against ischemic stroke in rats. Transl Stroke Res 5 (2014), 501–509.
    • (2014) Transl Stroke Res , vol.5 , pp. 501-509
    • Qi, Z.1    Yan, F.2    Shi, W.3    Zhang, C.4    Dong, W.5    Zhao, Y.6    Shen, J.7    Ji, X.8    Liu, K.J.9    Luo, Y.10
  • 36
    • 84875239001 scopus 로고    scopus 로고
    • NAD+ and nicotinamide: sex differences in cerebral ischemia
    • Siegel, C.S., McCullough, L.D., NAD+ and nicotinamide: sex differences in cerebral ischemia. Neuroscience 237 (2013), 223–231.
    • (2013) Neuroscience , vol.237 , pp. 223-231
    • Siegel, C.S.1    McCullough, L.D.2
  • 37
    • 79960994356 scopus 로고    scopus 로고
    • MiR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia
    • Siegel, C., Li, J., Liu, F., Benashski, S.E., McCullough, L.D., MiR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia. Proc Natl Acad Sci U S A 108 (2011), 11662–11667.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11662-11667
    • Siegel, C.1    Li, J.2    Liu, F.3    Benashski, S.E.4    McCullough, L.D.5
  • 38
    • 84893437275 scopus 로고    scopus 로고
    • Sex differences in behavioral outcome following neonatal hypoxia ischemia: Insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic brain injury
    • Smith, A.L., Alexander, M., Rosenkrantz, T.S., Sadek, M.L., Fitch, R.H., Sex differences in behavioral outcome following neonatal hypoxia ischemia: Insights from a clinical meta-analysis and a rodent model of induced hypoxic ischemic brain injury. Exp Neurol, 2014.
    • (2014) Exp Neurol
    • Smith, A.L.1    Alexander, M.2    Rosenkrantz, T.S.3    Sadek, M.L.4    Fitch, R.H.5
  • 39
    • 84961897442 scopus 로고    scopus 로고
    • Effects of sex and mild intrainsult hypothermia on neuropathology and neural reorganization following neonatal hypoxic ischemic brain injury in rats
    • Smith, A.L., Rosenkrantz, T.S., Fitch, R.H., Effects of sex and mild intrainsult hypothermia on neuropathology and neural reorganization following neonatal hypoxic ischemic brain injury in rats. Neural Plast, 2016, 2016, 2585230.
    • (2016) Neural Plast , vol.2016 , pp. 2585230
    • Smith, A.L.1    Rosenkrantz, T.S.2    Fitch, R.H.3
  • 41
    • 84910122496 scopus 로고    scopus 로고
    • Autophagy activation contributes to the neuroprotection of remote ischemic perconditioning against focal cerebral ischemia in rats
    • Su, J., Zhang, T., Wang, K., Zhu, T., Li, X., Autophagy activation contributes to the neuroprotection of remote ischemic perconditioning against focal cerebral ischemia in rats. Neurochem Res 39 (2014), 2068–2077.
    • (2014) Neurochem Res , vol.39 , pp. 2068-2077
    • Su, J.1    Zhang, T.2    Wang, K.3    Zhu, T.4    Li, X.5
  • 42
    • 84863842930 scopus 로고    scopus 로고
    • Hypoxic-ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria
    • Ten, V.S., Starkov, A., Hypoxic-ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria. Neurol Res Int, 2012, 2012, 542976.
    • (2012) Neurol Res Int , vol.2012 , pp. 542976
    • Ten, V.S.1    Starkov, A.2
  • 43
    • 84921419580 scopus 로고    scopus 로고
    • Genetic deletion of neuronal pentraxin 1 expression prevents brain injury in a neonatal mouse model of cerebral hypoxia-ischemia
    • Thatipamula, S., Al, R.M., Zhang, J., Hossain, M.A., Genetic deletion of neuronal pentraxin 1 expression prevents brain injury in a neonatal mouse model of cerebral hypoxia-ischemia. Neurobiol Dis 75 (2015), 15–30.
    • (2015) Neurobiol Dis , vol.75 , pp. 15-30
    • Thatipamula, S.1    Al, R.M.2    Zhang, J.3    Hossain, M.A.4
  • 44
    • 77949400068 scopus 로고    scopus 로고
    • Sex-specific responses to stroke
    • Turtzo, L.C., McCullough, L.D., Sex-specific responses to stroke. Future Neurol 5 (2010), 47–59.
    • (2010) Future Neurol , vol.5 , pp. 47-59
    • Turtzo, L.C.1    McCullough, L.D.2
  • 46
    • 84952682681 scopus 로고    scopus 로고
    • Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI
    • Waddell, J., Hanscom, M., Shalon, E.N., McKenna, M.C., McCarthy, M.M., Sex differences in cell genesis, hippocampal volume and behavioral outcomes in a rat model of neonatal HI. Exp Neurol 275:Pt 2 (2016), 285–295.
    • (2016) Exp Neurol , vol.275 , pp. 285-295
    • Waddell, J.1    Hanscom, M.2    Shalon, E.N.3    McKenna, M.C.4    McCarthy, M.M.5
  • 47
    • 84907163183 scopus 로고    scopus 로고
    • ARRB1/beta-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia
    • Wang, P., Xu, T.Y., Wei, K., Guan, Y.F., Wang, X., Xu, H., Su, D.F., Pei, G., Miao, C.Y., ARRB1/beta-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia. Autophagy 10 (2014), 1535–1548.
    • (2014) Autophagy , vol.10 , pp. 1535-1548
    • Wang, P.1    Xu, T.Y.2    Wei, K.3    Guan, Y.F.4    Wang, X.5    Xu, H.6    Su, D.F.7    Pei, G.8    Miao, C.Y.9
  • 50
    • 84955216091 scopus 로고    scopus 로고
    • In vivo longitudinal proton magnetic resonance spectroscopy on neonatal hypoxic-ischemic rat brain injury: Neuroprotective effects of acetyl-L-carnitine
    • Xu, S., Waddell, J., Zhu, W., Shi, D., Marshall, A.D., McKenna, M.C., Gullapalli, R.P., In vivo longitudinal proton magnetic resonance spectroscopy on neonatal hypoxic-ischemic rat brain injury: Neuroprotective effects of acetyl-L-carnitine. Magn Reson Med 74 (2015), 1530–1542.
    • (2015) Magn Reson Med , vol.74 , pp. 1530-1542
    • Xu, S.1    Waddell, J.2    Zhu, W.3    Shi, D.4    Marshall, A.D.5    McKenna, M.C.6    Gullapalli, R.P.7
  • 51
    • 84949495277 scopus 로고    scopus 로고
    • Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia
    • Yang, X., Hei, C., Liu, P., Song, Y., Thomas, T., Tshimanga, S., Wang, F., Niu, J., Sun, T., Li, P.A., Inhibition of mTOR Pathway by Rapamycin Reduces Brain Damage in Rats Subjected to Transient Forebrain Ischemia. Int J Biol Sci 11 (2015), 1424–1435.
    • (2015) Int J Biol Sci , vol.11 , pp. 1424-1435
    • Yang, X.1    Hei, C.2    Liu, P.3    Song, Y.4    Thomas, T.5    Tshimanga, S.6    Wang, F.7    Niu, J.8    Sun, T.9    Li, P.A.10
  • 52
    • 84935485803 scopus 로고    scopus 로고
    • Activation of autophagy in rat brain cells following focal cerebral ischemia reperfusion through enhanced expression of Atg1/pULK and LC3
    • Yu, J., Bao, C., Dong, Y., Liu, X., Activation of autophagy in rat brain cells following focal cerebral ischemia reperfusion through enhanced expression of Atg1/pULK and LC3. Mol Med Rep 12 (2015), 3339–3344.
    • (2015) Mol Med Rep , vol.12 , pp. 3339-3344
    • Yu, J.1    Bao, C.2    Dong, Y.3    Liu, X.4
  • 53
    • 64249104435 scopus 로고    scopus 로고
    • Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke
    • Yuan, M., Siegel, C., Zeng, Z., Li, J., Liu, F., McCullough, L.D., Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke. Exp Neurol 217 (2009), 210–218.
    • (2009) Exp Neurol , vol.217 , pp. 210-218
    • Yuan, M.1    Siegel, C.2    Zeng, Z.3    Li, J.4    Liu, F.5    McCullough, L.D.6
  • 54
    • 84947033848 scopus 로고    scopus 로고
    • Suppression of mitochondrial fission in experimental cerebral ischemia: the potential neuroprotective target of p38 MAPK inhibition
    • Zhang, X.M., Zhang, L., Wang, G., Niu, W., He, Z., Ding, L., Jia, J., Suppression of mitochondrial fission in experimental cerebral ischemia: the potential neuroprotective target of p38 MAPK inhibition. Neurochem Int 90 (2015), 1–8.
    • (2015) Neurochem Int , vol.90 , pp. 1-8
    • Zhang, X.M.1    Zhang, L.2    Wang, G.3    Niu, W.4    He, Z.5    Ding, L.6    Jia, J.7
  • 55
    • 84905388716 scopus 로고    scopus 로고
    • Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage
    • Zuo, W., Zhang, S., Xia, C.Y., Guo, X.F., He, W.B., Chen, N.H., Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage. Neuropharmacology 86 (2014), 103–115.
    • (2014) Neuropharmacology , vol.86 , pp. 103-115
    • Zuo, W.1    Zhang, S.2    Xia, C.Y.3    Guo, X.F.4    He, W.B.5    Chen, N.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.