Gene copy-number variations (CNVs) of complement C4 and C4A deficiency in genetic risk and pathogenesis of juvenile dermatomyositis

Annals of the Rheumatic Diseases

Volumn 75, Issue 9, 2016, Pages 1599-1606

  Lintner, Katherine E ^a   Patwardhan, Anjali ^a   Rider, Lisa G ^b   Abdul Aziz, Rabheh ^a   Wu, Yee Ling ^a   Lundström, Emeli ^c   Padyukov, Leonid ^c   Zhou, Bi ^a   Alhomosh, Alaaedin ^a   Newsom, David ^a   White, Peter ^a   Jones, Karla B ^a   O'Hanlon, Terrance P ^b   Miller, Frederick W ^b   Spencer, Charles H ^a   Yu, Chack Yung ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Autoimmune Diseases; Dermatomyositis; Disease Activity; Epidemiology; Gene Polymorphism

Indexed keywords

CHEMOKINE; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C4A; COMPLEMENT COMPONENT C4B; HLA DR3 ANTIGEN; HLA DRB1 ANTIGEN; INTERFERON; MUSCLE ENZYME; RNA; DEATH RECEPTOR 3; TNFRSF25 PROTEIN, HUMAN;

ARTICLE; C4 GENE; C4A GENE; C4B GENE; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; COPY NUMBER VARIATION; ERYTHROCYTE; FEMALE; GENE EXPRESSION; GENETIC RISK; GENOTYPE; HLA DR3 GENE; HLA DRB1 GENE; HUMAN; JUVENILE DERMATOMYOSITIS; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE; UPREGULATION; ADOLESCENT; BLOOD; CASE CONTROL STUDY; CAUCASIAN; DEFICIENCY; DERMATOMYOSITIS; GENETIC PREDISPOSITION; GENETICS; IMMUNE DEFICIENCY; PRESCHOOL CHILD; RISK FACTOR;

ADOLESCENT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COMPLEMENT C4; COMPLEMENT C4A; COMPLEMENT C4B; DERMATOMYOSITIS; DNA COPY NUMBER VARIATIONS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-DRB1 CHAINS; HUMANS; IMMUNOLOGIC DEFICIENCY SYNDROMES; MALE; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 25; RISK FACTORS;

EID: 84985992327     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2015-207762     Document Type: Article

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