-
1
-
-
65649148301
-
Serine carboxypeptidases in regulation of vasoconstriction and elastogenesis
-
Pshezhetsky, A. V.; Hinek, A. Serine carboxypeptidases in regulation of vasoconstriction and elastogenesis Trends Cardiovasc. Med. 2009, 19, 11-17 10.1016/j.tcm.2009.03.002
-
(2009)
Trends Cardiovasc. Med.
, vol.19
, pp. 11-17
-
-
Pshezhetsky, A.V.1
Hinek, A.2
-
2
-
-
0036112468
-
Angiotensin 1-9 and 1-7 release in human heart: Role of cathepsin A
-
Jackman, H. L.; Massad, M. G.; Sekosan, M.; Tan, F.; Brovkovych, V.; Marcic, B. M.; Erdos, E. G. Angiotensin 1-9 and 1-7 release in human heart: role of cathepsin A Hypertension 2002, 39, 976-981 10.1161/01.HYP.0000017283.67962.02
-
(2002)
Hypertension
, vol.39
, pp. 976-981
-
-
Jackman, H.L.1
Massad, M.G.2
Sekosan, M.3
Tan, F.4
Brovkovych, V.5
Marcic, B.M.6
Erdos, E.G.7
-
3
-
-
84908889440
-
Carboxyterminal protein processing in health and disease: Key actors and emerging technologies
-
Petrera, A.; Lai, Z. W.; Schilling, O. Carboxyterminal protein processing in health and disease: key actors and emerging technologies J. Proteome Res. 2014, 13, 4497-4504 10.1021/pr5005746
-
(2014)
J. Proteome Res.
, vol.13
, pp. 4497-4504
-
-
Petrera, A.1
Lai, Z.W.2
Schilling, O.3
-
4
-
-
0026660234
-
Inactivation of endothelin i by deamidase (lysosomal protective protein)
-
Jackman, H. L.; Morris, P. W.; Deddish, P. A.; Skidgel, R. A.; Erdos, E. G. Inactivation of endothelin I by deamidase (lysosomal protective protein) J. Biol. Chem. 1992, 267, 2872-2875
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2872-2875
-
-
Jackman, H.L.1
Morris, P.W.2
Deddish, P.A.3
Skidgel, R.A.4
Erdos, E.G.5
-
5
-
-
0025366352
-
Structure of the lysosomal neuraminidase-beta-galactosidase-carboxypeptidase multienzymic complex
-
Potier, M.; Michaud, L.; Tranchemontagne, J.; Thauvette, L. Structure of the lysosomal neuraminidase-beta-galactosidase-carboxypeptidase multienzymic complex Biochem. J. 1990, 267, 197-202 10.1042/bj2670197
-
(1990)
Biochem. J.
, vol.267
, pp. 197-202
-
-
Potier, M.1
Michaud, L.2
Tranchemontagne, J.3
Thauvette, L.4
-
6
-
-
0020172109
-
Molecular defect in combined beta-galactosidase and neuraminidase deficiency in man
-
D'Azzo, A.; Hoogeveen, A.; Reuser, A. J.; Robinson, D.; Galjaard, H. Molecular defect in combined beta-galactosidase and neuraminidase deficiency in man Proc. Natl. Acad. Sci. U. S. A. 1982, 79, 4535-4539 10.1073/pnas.79.15.4535
-
(1982)
Proc. Natl. Acad. Sci. U. S. A.
, vol.79
, pp. 4535-4539
-
-
D'Azzo, A.1
Hoogeveen, A.2
Reuser, A.J.3
Robinson, D.4
Galjaard, H.5
-
7
-
-
0033385805
-
Cathepsin A/protective protein: An unusual lysosomal multifunctional protein
-
Hiraiwa, M. Cathepsin A/protective protein: an unusual lysosomal multifunctional protein Cell. Mol. Life Sci. 1999, 56, 894-907 10.1007/s000180050482
-
(1999)
Cell. Mol. Life Sci.
, vol.56
, pp. 894-907
-
-
Hiraiwa, M.1
-
8
-
-
42149140537
-
Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1
-
Seyrantepe, V.; Hinek, A.; Peng, J.; Fedjaev, M.; Ernest, S.; Kadota, Y.; Canuel, M.; Itoh, K.; Morales, C. R.; Lavoie, J.; Tremblay, J.; Pshezhetsky, A. V. Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1 Circulation 2008, 117, 1973-1981 10.1161/CIRCULATIONAHA.107.733212
-
(2008)
Circulation
, vol.117
, pp. 1973-1981
-
-
Seyrantepe, V.1
Hinek, A.2
Peng, J.3
Fedjaev, M.4
Ernest, S.5
Kadota, Y.6
Canuel, M.7
Itoh, K.8
Morales, C.R.9
Lavoie, J.10
Tremblay, J.11
Pshezhetsky, A.V.12
-
9
-
-
84866333904
-
Novel beta-amino acid derivatives as inhibitors of cathepsin A
-
Ruf, S.; Buning, C.; Schreuder, H.; Horstick, G.; Linz, W.; Olpp, T.; Pernerstorfer, J.; Hiss, K.; Kroll, K.; Kannt, A.; Kohlmann, M.; Linz, D.; Hubschle, T.; Rutten, H.; Wirth, K.; Schmidt, T.; Sadowski, T. Novel beta-amino acid derivatives as inhibitors of cathepsin A J. Med. Chem. 2012, 55, 7636-7649 10.1021/jm300663n
-
(2012)
J. Med. Chem.
, vol.55
, pp. 7636-7649
-
-
Ruf, S.1
Buning, C.2
Schreuder, H.3
Horstick, G.4
Linz, W.5
Olpp, T.6
Pernerstorfer, J.7
Hiss, K.8
Kroll, K.9
Kannt, A.10
Kohlmann, M.11
Linz, D.12
Hubschle, T.13
Rutten, H.14
Wirth, K.15
Schmidt, T.16
Sadowski, T.17
-
10
-
-
84971526204
-
Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels
-
Petrera, A.; Gassenhuber, J.; Ruf, S.; Gunasekaran, D.; Esser, J.; Shahinian, J. H.; Hubschle, T.; Rutten, H.; Sadowski, T.; Schilling, O. Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels J. Transl. Med. 2016, 14, 153 10.1186/s12967-016-0907-8
-
(2016)
J. Transl. Med.
, vol.14
, pp. 153
-
-
Petrera, A.1
Gassenhuber, J.2
Ruf, S.3
Gunasekaran, D.4
Esser, J.5
Shahinian, J.H.6
Hubschle, T.7
Rutten, H.8
Sadowski, T.9
Schilling, O.10
-
11
-
-
74949133174
-
Comparative transcriptome analysis of human aorta atherosclerotic lesions and peripheral blood leukocytes from essential hypertension patients
-
Timofeeva, A. V.; Goriunova, L. E.; Khaspekov, G. L.; Il'inskaia, O. P.; Sirotkin, V. N.; Andreeva, E. R.; Tararak, E. M.; Bulkina, O. S.; Buza, V. V.; Britareva, V. V.; Karpov, I. A.; Bibilashvili, R. [Comparative transcriptome analysis of human aorta atherosclerotic lesions and peripheral blood leukocytes from essential hypertension patients] Kardiologiia 2009, 49, 27-38
-
(2009)
Kardiologiia
, vol.49
, pp. 27-38
-
-
Timofeeva, A.V.1
Goriunova, L.E.2
Khaspekov, G.L.3
Il'Inskaia, O.P.4
Sirotkin, V.N.5
Andreeva, E.R.6
Tararak, E.M.7
Bulkina, O.S.8
Buza, V.V.9
Britareva, V.V.10
Karpov, I.A.11
Bibilashvili, R.12
-
12
-
-
0034640357
-
Altered patterns of gene expression in response to myocardial infarction
-
Stanton, L. W.; Garrard, L. J.; Damm, D.; Garrick, B. L.; Lam, A.; Kapoun, A. M.; Zheng, Q.; Protter, A. A.; Schreiner, G. F.; White, R. T. Altered patterns of gene expression in response to myocardial infarction Circ. Res. 2000, 86, 939-945 10.1161/01.RES.86.9.939
-
(2000)
Circ. Res.
, vol.86
, pp. 939-945
-
-
Stanton, L.W.1
Garrard, L.J.2
Damm, D.3
Garrick, B.L.4
Lam, A.5
Kapoun, A.M.6
Zheng, Q.7
Protter, A.A.8
Schreiner, G.F.9
White, R.T.10
-
13
-
-
84973349017
-
Cathepsin A Mediates Susceptibility to Atrial Tachyarrhythmia and Impairment of Atrial Emptying Function in Zucker Diabetic Fatty Rats
-
Linz, D.; Hohl, M.; Dhein, S.; Ruf, S.; Reil, J. C.; Kabiri, M.; Wohlfart, P.; Verheule, S.; Bohm, M.; Sadowski, T.; Schotten, U. Cathepsin A Mediates Susceptibility to Atrial Tachyarrhythmia and Impairment of Atrial Emptying Function in Zucker Diabetic Fatty Rats Cardiovasc. Res. 2016, 110, 371 10.1093/cvr/cvw071
-
(2016)
Cardiovasc. Res.
, vol.110
, pp. 371
-
-
Linz, D.1
Hohl, M.2
Dhein, S.3
Ruf, S.4
Reil, J.C.5
Kabiri, M.6
Wohlfart, P.7
Verheule, S.8
Bohm, M.9
Sadowski, T.10
Schotten, U.11
-
14
-
-
84893850175
-
Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis
-
Tholen, S.; Biniossek, M. L.; Gansz, M.; Ahrens, T. D.; Schlimpert, M.; Kizhakkedathu, J. N.; Reinheckel, T.; Schilling, O. Double deficiency of cathepsins B and L results in massive secretome alterations and suggests a degradative cathepsin-MMP axis Cell. Mol. Life Sci. 2014, 71, 899-916 10.1007/s00018-013-1406-1
-
(2014)
Cell. Mol. Life Sci.
, vol.71
, pp. 899-916
-
-
Tholen, S.1
Biniossek, M.L.2
Gansz, M.3
Ahrens, T.D.4
Schlimpert, M.5
Kizhakkedathu, J.N.6
Reinheckel, T.7
Schilling, O.8
-
15
-
-
84957851489
-
Impact of cathepsin B on the interstitial fluid proteome of murine breast cancers
-
Gomez-Auli, A.; Hillebrand, L. E.; Biniossek, M. L.; Peters, C.; Reinheckel, T.; Schilling, O. Impact of cathepsin B on the interstitial fluid proteome of murine breast cancers Biochimie 2016, 122, 88 10.1016/j.biochi.2015.10.009
-
(2016)
Biochimie
, vol.122
, pp. 88
-
-
Gomez-Auli, A.1
Hillebrand, L.E.2
Biniossek, M.L.3
Peters, C.4
Reinheckel, T.5
Schilling, O.6
-
16
-
-
84926507971
-
Limma powers differential expression analyses for RNA-sequencing and microarray studies
-
Ritchie, M. E.; Phipson, B.; Wu, D.; Hu, Y.; Law, C. W.; Shi, W.; Smyth, G. K. limma powers differential expression analyses for RNA-sequencing and microarray studies Nucleic Acids Res. 2015, 43, e47 10.1093/nar/gkv007
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. e47
-
-
Ritchie, M.E.1
Phipson, B.2
Wu, D.3
Hu, Y.4
Law, C.W.5
Shi, W.6
Smyth, G.K.7
-
17
-
-
84876515907
-
STRING v9.1: Protein-protein interaction networks, with increased coverage and integration
-
Franceschini, A.; Szklarczyk, D.; Frankild, S.; Kuhn, M.; Simonovic, M.; Roth, A.; Lin, J.; Minguez, P.; Bork, P.; von Mering, C.; Jensen, L. J. STRING v9.1: protein-protein interaction networks, with increased coverage and integration Nucleic Acids Res. 2013, 41, D808-815 10.1093/nar/gks1094
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. D808-815
-
-
Franceschini, A.1
Szklarczyk, D.2
Frankild, S.3
Kuhn, M.4
Simonovic, M.5
Roth, A.6
Lin, J.7
Minguez, P.8
Bork, P.9
Von Mering, C.10
Jensen, L.J.11
-
18
-
-
84891796097
-
ProteomeXchange provides globally coordinated proteomics data submission and dissemination
-
Vizcaino, J. A.; Deutsch, E. W.; Wang, R.; Csordas, A.; Reisinger, F.; Rios, D.; Dianes, J. A.; Sun, Z.; Farrah, T.; Bandeira, N.; Binz, P. A.; Xenarios, I.; Eisenacher, M.; Mayer, G.; Gatto, L.; Campos, A.; Chalkley, R. J.; Kraus, H. J.; Albar, J. P.; Martinez-Bartolome, S.; Apweiler, R.; Omenn, G. S.; Martens, L.; Jones, A. R.; Hermjakob, H. ProteomeXchange provides globally coordinated proteomics data submission and dissemination Nat. Biotechnol. 2014, 32, 223-226 10.1038/nbt.2839
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 223-226
-
-
Vizcaino, J.A.1
Deutsch, E.W.2
Wang, R.3
Csordas, A.4
Reisinger, F.5
Rios, D.6
Dianes, J.A.7
Sun, Z.8
Farrah, T.9
Bandeira, N.10
Binz, P.A.11
Xenarios, I.12
Eisenacher, M.13
Mayer, G.14
Gatto, L.15
Campos, A.16
Chalkley, R.J.17
Kraus, H.J.18
Albar, J.P.19
Martinez-Bartolome, S.20
Apweiler, R.21
Omenn, G.S.22
Martens, L.23
Jones, A.R.24
Hermjakob, H.25
more..
-
19
-
-
84901418451
-
Network analyses reveal pervasive functional regulation between proteases in the human protease web
-
Fortelny, N.; Cox, J. H.; Kappelhoff, R.; Starr, A. E.; Lange, P. F.; Pavlidis, P.; Overall, C. M. Network analyses reveal pervasive functional regulation between proteases in the human protease web PLoS Biol. 2014, 12, e1001869 10.1371/journal.pbio.1001869
-
(2014)
PLoS Biol.
, vol.12
, pp. e1001869
-
-
Fortelny, N.1
Cox, J.H.2
Kappelhoff, R.3
Starr, A.E.4
Lange, P.F.5
Pavlidis, P.6
Overall, C.M.7
-
20
-
-
84866660710
-
The role of calpains in myocardial remodelling and heart failure
-
Letavernier, E.; Zafrani, L.; Perez, J.; Letavernier, B.; Haymann, J. P.; Baud, L. The role of calpains in myocardial remodelling and heart failure Cardiovasc. Res. 2012, 96, 38-45 10.1093/cvr/cvs099
-
(2012)
Cardiovasc. Res.
, vol.96
, pp. 38-45
-
-
Letavernier, E.1
Zafrani, L.2
Perez, J.3
Letavernier, B.4
Haymann, J.P.5
Baud, L.6
-
21
-
-
0038337815
-
The calpain system
-
Goll, D. E.; Thompson, V. F.; Li, H.; Wei, W.; Cong, J. The calpain system Physiol. Rev. 2003, 83, 731-801 10.1152/physrev.00029.2002
-
(2003)
Physiol. Rev.
, vol.83
, pp. 731-801
-
-
Goll, D.E.1
Thompson, V.F.2
Li, H.3
Wei, W.4
Cong, J.5
-
22
-
-
34247121951
-
Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis
-
Galvez, A. S.; Diwan, A.; Odley, A. M.; Hahn, H. S.; Osinska, H.; Melendez, J. G.; Robbins, J.; Lynch, R. A.; Marreez, Y.; Dorn, G. W., 2nd Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis Circ. Res. 2007, 100, 1071-1078 10.1161/01.RES.0000261938.28365.11
-
(2007)
Circ. Res.
, vol.100
, pp. 1071-1078
-
-
Galvez, A.S.1
Diwan, A.2
Odley, A.M.3
Hahn, H.S.4
Osinska, H.5
Melendez, J.G.6
Robbins, J.7
Lynch, R.A.8
Marreez, Y.9
Dorn, G.W.10
-
23
-
-
84874615947
-
Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome
-
Tholen, S.; Biniossek, M. L.; Gansz, M.; Gomez-Auli, A.; Bengsch, F.; Noel, A.; Kizhakkedathu, J. N.; Boerries, M.; Busch, H.; Reinheckel, T.; Schilling, O. Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome Mol. Cell. Proteomics 2013, 12, 611-625 10.1074/mcp.M112.017962
-
(2013)
Mol. Cell. Proteomics
, vol.12
, pp. 611-625
-
-
Tholen, S.1
Biniossek, M.L.2
Gansz, M.3
Gomez-Auli, A.4
Bengsch, F.5
Noel, A.6
Kizhakkedathu, J.N.7
Boerries, M.8
Busch, H.9
Reinheckel, T.10
Schilling, O.11
-
24
-
-
84880589600
-
Arginine vasopressin enhances cell survival via a G protein-coupled receptor kinase 2/beta-arrestin1/extracellular-regulated kinase 1/2-dependent pathway in H9c2 cells
-
Zhu, W.; Tilley, D. G.; Myers, V. D.; Coleman, R. C.; Feldman, A. M. Arginine vasopressin enhances cell survival via a G protein-coupled receptor kinase 2/beta-arrestin1/extracellular-regulated kinase 1/2-dependent pathway in H9c2 cells Mol. Pharmacol. 2013, 84, 227-235 10.1124/mol.113.086322
-
(2013)
Mol. Pharmacol.
, vol.84
, pp. 227-235
-
-
Zhu, W.1
Tilley, D.G.2
Myers, V.D.3
Coleman, R.C.4
Feldman, A.M.5
-
25
-
-
33644658460
-
Oxidative stress and lysosomes: CNS-related consequences and implications for lysosomal enhancement strategies and induction of autophagy
-
Butler, D.; Bahr, B. A. Oxidative stress and lysosomes: CNS-related consequences and implications for lysosomal enhancement strategies and induction of autophagy Antioxid. Redox Signaling 2006, 8, 185-196 10.1089/ars.2006.8.185
-
(2006)
Antioxid. Redox Signaling
, vol.8
, pp. 185-196
-
-
Butler, D.1
Bahr, B.A.2
-
26
-
-
30044436438
-
Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: Implication for endothelial cell apoptosis
-
Haendeler, J.; Popp, R.; Goy, C.; Tischler, V.; Zeiher, A. M.; Dimmeler, S. Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis J. Biol. Chem. 2005, 280, 42945-42951 10.1074/jbc.M506985200
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 42945-42951
-
-
Haendeler, J.1
Popp, R.2
Goy, C.3
Tischler, V.4
Zeiher, A.M.5
Dimmeler, S.6
-
27
-
-
33644643603
-
Oxidative stress and autophagy
-
Kiffin, R.; Bandyopadhyay, U.; Cuervo, A. M. Oxidative stress and autophagy Antioxid. Redox Signaling 2006, 8, 152-162 10.1089/ars.2006.8.152
-
(2006)
Antioxid. Redox Signaling
, vol.8
, pp. 152-162
-
-
Kiffin, R.1
Bandyopadhyay, U.2
Cuervo, A.M.3
-
28
-
-
58149350129
-
The proteasome and its role in the degradation of oxidized proteins
-
Jung, T.; Grune, T. The proteasome and its role in the degradation of oxidized proteins IUBMB Life 2008, 60, 743-752 10.1002/iub.114
-
(2008)
IUBMB Life
, vol.60
, pp. 743-752
-
-
Jung, T.1
Grune, T.2
-
29
-
-
84955205182
-
Tolerability, safety and pharmacokinetics of the novel Cathepsin A inhibitor SAR164653 in healthy subjects
-
Tillner, J.; Paehler, T.; Lukacs, Z.; Ruf, S.; Sadowski, T.; Pinquier, J.-L.; Ruetten, H.; Lehmann, A. Tolerability, safety and pharmacokinetics of the novel Cathepsin A inhibitor SAR164653 in healthy subjects Clin. Pharm. Drug Dev. 2016, 5, 57 10.1002/cpdd.201
-
(2016)
Clin. Pharm. Drug Dev.
, vol.5
, pp. 57
-
-
Tillner, J.1
Paehler, T.2
Lukacs, Z.3
Ruf, S.4
Sadowski, T.5
Pinquier, J.-L.6
Ruetten, H.7
Lehmann, A.8
|