Nitroxyl (HNO) reduces endothelial and monocyte activation and promotes M2 macrophage polarization

Clinical Science

Volumn 130, Issue 18, 2016, Pages 1629-1640

  Andrews, Karen L ^a,b   Sampson, Amanda K ^b   Irvine, Jennifer C ^b   Shihata, Waled A ^a,b   Michell, Danielle L ^a   Lumsden, Natalie G ^a   Lim, Chloe ^a   Huet, Olivier ^a   Drummond, Grant R ^b   Kemp Harper, Barbara K ^b   Chin Dusting, Jaye P F ^a,b  

^a BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^b MONASH UNIVERSITY   (Australia)

Author keywords

Inflammation; Leucocyte adhesion; Nitrate tolerance; Nitric oxide; Nitroxyl

Indexed keywords

ANGELI SALT; CARDIOVASCULAR AGENT; GLYCERYL TRINITRATE; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; ISOPROPYLAMINE NONOATE; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; NITROGEN OXIDE; NITROXYL;

ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AORTA; ARTICLE; ATHEROSCLEROSIS; CELL ACTIVATION; CELL DIFFERENTIATION; CELL POLARITY; CONTROLLED STUDY; CYTOKINE RELEASE; ENDOTHELIUM CELL; GENE EXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE ACTIVATION; LEUKOCYTE ADHERENCE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR ENDOTHELIUM; VASODILATATION; ANIMAL; C57BL MOUSE; CYTOLOGY; DRUG EFFECTS; IMMUNOLOGY; PATHOPHYSIOLOGY;

ANIMALS; AORTA; ATHEROSCLEROSIS; CELL POLARITY; CHEMOKINE CCL2; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MONOCYTES; NITROGEN OXIDES;

EID: 84985867069     PISSN: 01435221     EISSN: 14708736     Source Type: Journal    
DOI: 10.1042/CS20160097     Document Type: Article

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