Perioperative antiplatelet therapy and cardiovascular outcomes in patients undergoing joint and spine surgery

Journal of Clinical Anesthesia

Volumn 35, Issue , 2016, Pages 163-169

  Smilowitz, Nathaniel R ^a   Oberweis, Brandon S ^b   Nukala, Swetha ^a   Rosenberg, Andrew ^a   Stuchin, Steven ^a   Iorio, Richard ^a   Errico, Thomas ^a   Radford, Martha J ^a   Berger, Jeffrey S ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Medicine   (United States)

Author keywords

Antiplatelet; Aspirin; Bleeding; Cardiovascular; Coronary artery disease; Myocardial infarction; Myocardial injury; Orthopedic surgery; Perioperative; Transfusion

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; TROPONIN I; ANTITHROMBOCYTIC AGENT;

ADULT; ANTICOAGULANT THERAPY; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR EFFECT; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; COMORBIDITY; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; ERYTHROCYTE TRANSFUSION; FEMALE; HEART INFARCTION; HEART MUSCLE INJURY; HIGH RISK PATIENT; HIP SURGERY; HOSPITAL PATIENT; HUMAN; INCIDENCE; KNEE SURGERY; MAJOR CLINICAL STUDY; MALE; MANAGED CARE; OUTCOME ASSESSMENT; PERIOPERATIVE PERIOD; POPULATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SPINE SURGERY; TERTIARY CARE CENTER; ADVERSE EFFECTS; AGED; CHEMICALLY INDUCED; COMPLICATION; MIDDLE AGED; MORTALITY; OPERATIVE BLOOD LOSS; ORTHOPEDIC SURGERY; PROCEDURES; STATISTICS AND NUMERICAL DATA; THROMBOSIS; TREATMENT OUTCOME;

AGED; ASPIRIN; BLOOD LOSS, SURGICAL; CORONARY ARTERY DISEASE; ERYTHROCYTE TRANSFUSION; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; ORTHOPEDIC PROCEDURES; PERIOPERATIVE CARE; PLATELET AGGREGATION INHIBITORS; POSTOPERATIVE HEMORRHAGE; RETROSPECTIVE STUDIES; TERTIARY CARE CENTERS; THROMBOSIS; TREATMENT OUTCOME;

EID: 84984853581     PISSN: 09528180     EISSN: 18734529     Source Type: Journal    
DOI: 10.1016/j.jclinane.2016.07.028     Document Type: Article

References (30)

1. [1] Weiss, AJ, Elixhauseer, A, Trends in operating room procedures in U.S. hospitals, 2001–2011. HCUP statistical brief #171. 2014, Agency for Healthcare Research and Quality, Rockville, MD.
2. [2] Steiner, C, Andrews, R, Barrett, M, Weiss, A, HCUP projections: mobility/orthopedic procedures 2003 to 2012. Report # 2012–03. 2012, U.S. Agency for Healthcare Research and Quality [ http://www.hcup-us.ahrq.gov/reports/projections/2012-03.pdf. Published September 20, 2012. Accessed November 1, 2014].
3. [3] Landesberg, G, Beattie, WS, Mosseri, M, Jaffe, AS, Alpert, JS, Perioperative myocardial infarction. Circulation 119 (2009), 2936–2944.
4. [4] Devereaux, PJ, Xavier, D, Pogue, J, Guyatt, G, Sigamani, A, Garutti, I, et al. Characteristics and short-term prognosis of perioperative myocardial infarction in patients undergoing noncardiac surgery: a cohort study. Ann Intern Med 154 (2011), 523–528.
5. [5] Lalmohamed, A, Vestergaard, P, Klop, C, Grove, EL, de Boer, A, Leufkens, HG, et al. Timing of acute myocardial infarction in patients undergoing total hip or knee replacement: a nationwide cohort study. Arch Intern Med 172 (2012), 1229–1235.
6. [6] Thygesen, K, Alpert, JS, Jaffe, AS, Simoons, ML, Chaitman, BR, White, HD, et al. Third universal definition of myocardial infarction. J Am Coll Cardiol 60 (2012), 1581–1598.
7. [7] Redfern, G, Rodseth, RN, Biccard, BM, Outcomes in vascular surgical patients with isolated postoperative troponin leak: a meta-analysis. Anaesthesia 66 (2011), 604–610.
8. [8] van Waes, JA, Nathoe, HM, de Graaff, JC, Kemperman, H, de Borst, GJ, Peelen, LM, et al. Myocardial injury after noncardiac surgery and its association with short-term mortality. Circulation 127 (2013), 2264–2271.
9. [9] Vascular Events In Noncardiac Surgery Patients Cohort Evaluation Study I, Devereaux, PJ, Chan, MT, Alonso-Coello, P, Walsh, M, Berwanger, O, et al. Association between postoperative troponin levels and 30-day mortality among patients undergoing noncardiac surgery. JAMA 307 (2012), 2295–2304.
10. [10] Botto, F, Alonso-Coello, P, Chan, MT, Villar, JC, Xavier, D, Srinathan, S, et al. Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes. Anesthesiology 120 (2014), 564–578.
11. [11] Naesh, O, Friis, JT, Hindberg, I, Winther, K, Platelet function in surgical stress. Thromb Haemost 54 (1985), 849–852.
12. [12] Oberweis, BS, Cuff, G, Rosenberg, A, Pardo, L, Nardi, MA, Guo, Y, et al. Platelet aggregation and coagulation factors in orthopedic surgery. J Thromb Thrombolysis 38 (2014), 430–438.
13. [13] Antithrombotic Trialists, C, Baigent, C, Blackwell, L, Collins, R, Emberson, J, Godwin, J, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 373 (2009), 1849–1860.
14. [14] Oberweis, BS, Nukala, S, Rosenberg, A, Guo, Y, Stuchin, S, Radford, MJ, et al. Thrombotic and bleeding complications after orthopedic surgery. Am Heart J 165 (2013), 427–433 [e1].
15. [15] Devereaux, PJ, Mrkobrada, M, Sessler, DI, Leslie, K, Alonso-Coello, P, Kurz, A, et al. Aspirin in patients undergoing noncardiac surgery. N Engl J Med 370 (2014), 1494–1503.
16. [16] Kilic, A, Sultan, IS, Arnaoutakis, GJ, Black, JH III, Reifsnyder, T, Significant differences between vascular and nonvascular surgeons in the perioperative management of antiplatelet therapies in patients with coronary stents. Ann Vasc Surg 29 (2015), 526–533 [e2].
17. [17] Gerstein, NS, Charlton, GA, Questions linger over POISE-2 and perioperative aspirin management. Evid Based Med 19 (2014), 224–225.
18. [18] Group, PS, Devereaux, PJ, Yang, H, Yusuf, S, Guyatt, G, Leslie, K, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet 371 (2008), 1839–1847.
19. [19] Garcia, S, Marston, N, Sandoval, Y, Pierpont, G, Adabag, S, Brenes, J, et al. Prognostic value of 12-lead electrocardiogram and peak troponin I level after vascular surgery. J Vasc Surg 57 (2013), 166–172.
20. [20] Fleisher, LA, Beckman, JA, Brown, KA, Calkins, H, Chaikof, EL, Fleischmann, KE, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 2002 guidelines on perioperative cardiovascular evaluation for noncardiac surgery) developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, Society for Vascular Medicine and Biology, and Society for Vascular Surgery. J Am Coll Cardiol 50 (2007), e159–e241.
21. [21] Ausset, S, Auroy, Y, Lambert, E, Vest, P, Plotton, C, Rigal, S, et al. Cardiac troponin I release after hip surgery correlates with poor long-term cardiac outcome. Eur J Anaesthesiol 25 (2008), 158–164.
22. [22] Chong, CP, Lam, QT, Ryan, JE, Sinnappu, RN, Lim, WK, Incidence of post-operative troponin I rises and 1-year mortality after emergency orthopaedic surgery in older patients. Age Ageing 38 (2009), 168–174.
23. [23] Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet, 355, 2000, 1295–1302.
24. [24] Vaishnava, P, Eagle, KA, The yin and yang of perioperative medicine. N Engl J Med 370 (2014), 1554–1555.
25. [25] Oscarsson, A, Gupta, A, Fredrikson, M, Jarhult, J, Nystrom, M, Pettersson, E, et al. To continue or discontinue aspirin in the perioperative period: a randomized, controlled clinical trial. Br J Anaesth 104 (2010), 305–312.
26. [26] Wolf, AM, Pucci, MJ, Gabale, SD, McIntyre, CA, Irizarry, AM, Kennedy, EP, et al. Safety of perioperative aspirin therapy in pancreatic operations. Surgery 155 (2014), 39–46.
27. [27] Cuellar, JM, Petrizzo, A, Vaswani, R, Goldstein, JA, Bendo, JA, Does aspirin administration increase perioperative morbidity in patients with cardiac stents undergoing spinal surgery?. Spine (Phila Pa 1976) 40 (2015), 629–635.
28. [28] Fleisher, LA, Fleischmann, KE, Auerbach, AD, Barnason, SA, Beckman, JA, Bozkurt, B, et al. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol 64 (2014), e77–e137.
29. [29] Bangalore, S, Kumar, S, Fusaro, M, Amoroso, N, Attubato, MJ, Feit, F, et al. Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials. Circulation 125 (2012), 2873–2891.
30. [30] Oberweis, B.S., Smilowitz, N.R., Nukala, S., Rosenberg, A., Xu, J., Stuchin, S., et al. Relation of perioperative elevation of troponin to long-term mortality after orthopedic surgery. Am J Cardiol 115:12 (2015 Jun 15), 1643–1648.