Incidence of post-operative troponin I rises and 1-year mortality after emergency orthopaedic surgery in older patients

Age and Ageing

Volumn 38, Issue 2, 2009, Pages 168-174

  Chong, Carol P ^a   Lam, Que T ^a   Ryan, Julie E ^a   Sinnappu, Rabindra N ^a   Lim, Wen Kwang ^a,b  

^a NORTHERN HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Aged; Cardiac outcome; Fracture; Mortality; Orthopaedic surgery; Troponin I

Indexed keywords

TROPONIN I;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; CONGESTIVE HEART FAILURE; EMERGENCY SURGERY; FEMALE; GERIATRIC SURGERY; HEART ARRHYTHMIA; HEART ATRIUM FIBRILLATION; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; ORTHOPEDIC SURGERY; PERIOPERATIVE PERIOD; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; SURGICAL MORTALITY; SURVIVAL;

AGED; AGED, 80 AND OVER; AGING; EMERGENCY MEDICAL SERVICES; FEMALE; FRACTURES, BONE; HEART DISEASES; HUMANS; INCIDENCE; INPATIENTS; MALE; MIDDLE AGED; ORTHOPEDIC PROCEDURES; OUTPATIENTS; POSTOPERATIVE COMPLICATIONS; PREDICTIVE VALUE OF TESTS; RISK FACTORS; TROPONIN I;

EID: 61449176129     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afn231     Document Type: Article

References (28)

1. Devereaux PJ, Goldman L, Cook DJ, Gilbert K, Leslie K, Guyatt GH. Perioperative cardiac events in patients undergoing noncardiac surgery: a review of the magnitude of the problem, the pathophysiology of the events and methods to estimate and communicate risk. CMAJ: Can Med Assoc J 2005; 173: 627-34.
2. Lam Q, Black M, Youdell O, Spilsbury H, Schneider HG. Performance evaluation and subsequent clinical experience with the Abbott Automated Architect STAT Troponin-I Assay. Clin Chem 2006; 52: 298-300.
3. Babuin L, Jaffe A. Troponin: The biomarker of choice for the detection of cardiac injury. CMAJ 2005; 173: 1191-202.
4. Jules-Elysee K, Urban MK, Urquhart B, Milman S. Troponin I as a diagnostic marker of a perioperative myocardial infarction in the orthopedic population. J Clin Anesth 2001; 13: 556-60.
5. Adams JE, III, Bodor G, Davila-Roman V et al. Cardiac Troponin I - a marker with high specificity for cardiac injury. Circulation 1993; 88: 101-6.
6. Thygesen K, Alpert JS, White HD, on behalf of the Joint ESCAAHAWHFTFftRoMI. Universal definition of myocardial infarction. J Am Coll Cardiol 2007; 50: 2173-95.
7. Landesberg G, Shatz V, Akopnik I et al. Association of cardiac troponin, CK-MB, and postoperative myocardial ischemia with long-term survival after major vascular surgery [see comment]. J Am Coll Cardiol 2003; 42: 1547-54.
8. Devereaux PJ, Goldman L, Yusuf S, Gilbert K, Leslie K, Guyatt GH. Surveillance and prevention of major perioperative ischemic cardiac events in patients undergoing noncardiac surgery: A review. CMAJ: Can Med Assoc J 2005; 173: 779-88.
9. Fleisher LA, Beckman JA, Brown KA et al. ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Circulation 2007; 116: 1971-96.
10. Mouzopoulos G, Kouvaris C, Antonopoulos D et al. Perioperative creatine phosphokinase (CPK) and troponin I trends after elective hip surgery. J Trauma Inj Infect Crit Care 2007; 63: 388-93.
11. Ausset S, Auroy Y, Lambert E et al. Cardiac troponin I release after hip surgery correlates with poor long-term cardiac outcome. Eur J Anaesthesiol 2008; 25: 158-64.
12. Rapp HJ, Rabethge S, Luiz T, Haux P. Perioperative ST-segment depression and troponin T release. Identification of patients with highest risk for myocardial damage. Acta Anaesthesiol Scand 1999; 43: 124-9.
13. Metzler H, Gries M, Rehak P, Lang T, Fruhwald S, Toller W. Perioperative myocardial cell injury: The role of troponins. Br J Anaesth 1997; 78: 386-90.
14. Bursi F, Babuin L, Barbieri A et al. Vascular surgery patients: perioperative and long-term risk according to the ACC/AHA guidelines, the additive role of post-operative troponin elevation [see comment]. Eur Heart J 2005; 26: 2448-56.
15. Filipovic M, Jeger RV, Girard T et al. Predictors of long-term mortality and cardiac events in patients with known or suspected coronary artery disease who survive major noncardiac surgery [see comment]. Anaesthesia 2005; 60: 5-11.
16. Kim LJ, Martinez EA, Faraday N, et al. Cardiac troponin I predicts short-term mortality in vascular surgery patients. [see comment]. Circulation 2002; 106: 2366-71.
17. Higham H, Sear JW, Sear YM, Kemp M, Hooper RJL, Foex P. Peri-operative troponin I concentration as a marker of long-term postoperative adverse cardiac outcomes - a study in high-risk surgical patients. Anaesthesia 2004; 59: 318-23.
18. Adams JE, 3rd, Sicard GA, Allen BT et al. Diagnosis of perioperative myocardial infarction with measurement of cardiac troponin I [see comment]. N Engl J Med 1994; 330: 670-4.
19. Badner NH, Knill RL, Brown JE, Novick TV, Gelb AW. Myocardial infarction after noncardiac surgery. Anesthesiology 1998; 88: 572-8.
20. Bueti J, Krahn J, Karpinski M, Bohm C, Fine A, Rigatto C. Troponin I testing in dialysis patients presenting to the emergency room: Does troponin I predict the 30-day outcome?. Nephron Clin Pract 2006; 103: 129-36.
21. Lim W, Cook DJ, Griffith LE, Crowther MA, Devereaux PJ. Elevated cardiac troponin levels in critically ill patients: Prevalence, incidence, and outcomes. Am J Crit Care 2006; 15: 280-8; quiz 289.
22. Mahajan N, Mehta Y, Rose M, Shani J, Lichstein E. Elevated troponin level is not synonymous with myocardial infarction. Int J Cardiol 2006; 111: 442-9.
23. Mangano DT, Goldman L. Preoperative assessment of patients with known or suspected coronary disease. N Engl J Med 1995; 333: 1750-6.
24. Boufous S, Finch C, Lord S. Incidence of hip fracture in New South Wales: Are our efforts having an effect? Med J Aust 2004; 180: 623-6.
25. Goldacre M, Roberts S, Yeates D. Mortality after admission to hospital with fractured neck of femur: Database study. BMJ 2002; 325: 868-9.
26. Chong C, Christou J, Fitzpatrick K, Wee R, Lim WK. Description of an orthopaedic-geriatric model of care in Australia with 3 years data. Geriatr Gerontol Int 2008; 8: 86-92.
27. Fisher AA, Southcott EK, Srikusalanukul W et al. Relationships between myocardial injury, all-cause mortality, vitamin D, PTH, and biochemical bone turnover markers in older patients with hip fractures. Ann Clin Lab Sci 2007; 37: 222-32.
28. Lucreziotti S, Foroni C, Fiorentini C. Perioperative myocardial infarction in noncardiac surgery: The diagnostic and prognostic role of cardiac troponins. J Intern Med 2002; 252: 11-20.