Glimpse of natural selection of long-lived T-cell clones in healthy life

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 35, 2016, Pages 9858-9863

  Zhang, Baojun ^a   Jia, Qingzhu ^b   Bock, Cheryl ^a   Chen, Gang ^b   Yu, Haili ^b   Ni, Qingshan ^b   Wan, Ying ^b   Li, Qijing ^a   Zhuang, Yuan ^a  

^a DUKE UNIVERSITY   (United States)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Aging; Lineage tracking; T regulatory cells; TCR repertoire; Tolerance

Indexed keywords

ANIMAL CELL; ANTIGEN SPECIFICITY; CD4+ T LYMPHOCYTE; CELL AGING; CELL CLONE; CELL TRANSFER; COMPLEMENTARITY DETERMINING REGION; CONFERENCE PAPER; CONTROLLED STUDY; GENE REARRANGEMENT; HOMEOSTASIS; IMMUNOLOGICAL TOLERANCE; MOUSE; NATURAL SELECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; THYMUS; 129 MOUSE; AGING; ANIMAL; CD8+ T LYMPHOCYTE; CYTOLOGY; GENETIC SELECTION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; METABOLISM; TRANSGENIC MOUSE;

CYTOKINE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR;

AGING; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CLONE CELLS; CYTOKINES; FORKHEAD TRANSCRIPTION FACTORS; HOMEOSTASIS; IMMUNOLOGIC MEMORY; MICE, 129 STRAIN; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; SELECTION, GENETIC; T-LYMPHOCYTES; T-LYMPHOCYTES, REGULATORY; THYMUS GLAND;

EID: 84984698714     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1601634113     Document Type: Article

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