δ-Aminolevulinate dehydratase inhibition by 2,3-dimercaptopropanol is mediated by chelation of zinc from a site involved in maintaining cysteinyl residues in a reduced state

Pharmacology and Toxicology

Volumn 83, Issue 3, 1998, Pages 95-103

  Emanuelli, Tatiana ^a,b   Rocha, João Batista T ^a   Pereira, Maria Ester ^a   Nascimento, Paulo C ^a   Souza, Diogo O G ^b   Beber, Flávio A ^a  

^a FEDERAL UNIVERSITY OF SANTA MARIA   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DIMERCAPROL; PORPHOBILINOGEN SYNTHASE; ZINC;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CHELATION; DRUG INHIBITION; DRUG RECEPTOR BINDING; ENZYME ACTIVITY; ENZYME INHIBITION; HEAVY METAL POISONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RESIDUE ANALYSIS;

ANIMALIA; BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 84984590339     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1998.tb01451.x     Document Type: Article

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