Phase 2 trial of linifanib (ABT-869) in patients with unresectable or metastatic hepatocellular carcinoma

Cancer

Volumn 119, Issue 2, 2013, Pages 380-387

  Toh, Han Chong ^a   Chen, Pei Jer ^b   Carr, Brian I ^c,i   Knox, Jennifer J ^d   Gill, Sharlene ^e   Ansell, Peter ^f   McKeegan, Evelyn M ^f   Dowell, Barry ^f   Pedersen, Michelle ^f   Qin, Qin ^f   Qian, Jiang ^f   Scappaticci, Frank A ^g   Ricker, Justin L ^f   Carlson, Dawn M ^f   Yong, Wei Peng ^h  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e BRITISH COLUMBIA CANCER AGENCY   (Canada)

^f ABBOTT LABORATORIES   (United States)

^g GENENTECH INC   (United States)

^h NATIONAL UNIVERSITY HOSPITAL   (Singapore)

ⁱ IRCCS de Bellis Medical Center   (Italy)

Author keywords

angiogenesis; hepatocellular carcinoma (HCC); linifanib; platelet derived growth factor receptor (PDGFR); sorafenib; vascular endothelial growth factor receptor (VEGFR)

Indexed keywords

CA 125 ANTIGEN; CYTOKERATIN FRAGMENT 21.1; DECARBOXYPROTHROMBIN; KERATIN; LINIFANIB; TUMOR MARKER; UNCLASSIFIED DRUG;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANEMIA; ARTICLE; ASIAN; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BEDTIME DOSAGE; BILIRUBIN BLOOD LEVEL; CANCER GROWTH; CANCER PROGNOSIS; CANCER SURVIVAL; CHILD PUGH SCORE; CLINICAL ARTICLE; DECREASED APPETITE; DIARRHEA; DRUG EFFICACY; DRUG ERUPTION; DRUG SAFETY; FATIGUE; FEMALE; HAND FOOT SYNDROME; HUMAN; HYPERTENSION; LEUKOPENIA; LIVER CELL CARCINOMA; LIVER FUNCTION; MALE; METASTASIS POTENTIAL; MULTICENTER STUDY; NEUTROPENIA; OPEN STUDY; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN BLOOD LEVEL; PROTEINURIA; SIDE EFFECT; SYSTEMIC THERAPY; THROMBOCYTOPENIA; TREATMENT RESPONSE; VOMITING;

EID: 84984559340     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.27758     Document Type: Article

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