A systematic review of Fusobacterium necrophorum-positive acute tonsillitis: prevalence, methods of detection, patient characteristics, and the usefulness of the Centor score

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 35, Issue 12, 2016, Pages 1903-1912

  Klug, T E ^a   Rusan, M ^a,b   Fuursted, K ^c   Ovesen, T ^d   Jorgensen, A W ^e  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b HARVARD MEDICAL SCHOOL   (United States)

^c STATENS SERUM INSTITUT   (Denmark)

^d Region Hospital West   (Denmark)

^e AALBORG UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA;

AGE; ASYMPTOMATIC INFECTION; BACTERIAL LOAD; BACTERIUM CULTURE; BACTERIUM ISOLATION; CENTOR SCORE; HUMAN; LEMIERRE SYNDROME; NONHUMAN; POLYMERASE CHAIN REACTION; PREVALENCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RESPIRATORY TRACT DISEASE ASSESSMENT; REVIEW; SMOKING; SORE THROAT; STREPTOCOCCUS GROUP A; SYSTEMATIC REVIEW; FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NECROPHORUM; ISOLATION AND PURIFICATION; MICROBIOLOGY; PATHOLOGY; RISK FACTOR; TONSILLITIS;

FUSOBACTERIUM INFECTIONS; FUSOBACTERIUM NECROPHORUM; HUMANS; PREVALENCE; RISK FACTORS; TONSILLITIS;

EID: 84983751868     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-016-2757-y     Document Type: Review

References (26)

1. ESCMID Sore Throat Guideline Group, Pelucchi C, Grigoryan L, Galeone C, Esposito S, Huovinen P, Little P, Verheij T (2012) Guideline for the management of acute sore throat. Clin Microbiol Infect 18:1–28. doi:10.1111/j.1469-0691.2012.03766.x
2. Hedin K, Bieber L, Lindh M, Sundqvist M (2015) The aetiology of pharyngotonsillitis in adolescents and adults - Fusobacterium necrophorum is commonly found. Clin Microbiol Infect 21:263.e1–263.e7. doi:10.1016/j.cmi.2014.08.020
3. Shulman ST, Tanz RR (2010) Group A streptococcal pharyngitis and immune-mediated complications: from diagnosis to management. Expert Rev Anti Infect Ther 8:137–150
4. Centor RM, Witherspoon JM, Dalton HP, Brody CE, Link K (1981) The diagnosis of strep throat in adults in the emergency room. Med Decis Making 1:239–246
5. Tan ZL, Nagaraja TG, Chengappa MM (1996) Fusobacterium necrophorum infections: virulence factors, pathogenic mechanism and control measures. Vet Res Commun 20:113–140
6. Hagelskjaer Kristensen L, Prag J (2008) Lemierre’s syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey. Eur J Clin Microbiol Infect Dis 27:779–789
7. Ehlers Klug T, Rusan M, Fuursted K, Ovesen T (2009) Fusobacterium necrophorum: most prevalent pathogen in peritonsillar abscess in Denmark. Clin Infect Dis 49:1467–1472
8. Klug TE, Henriksen JJ, Fuursted K, Ovesen T (2011) Significant pathogens in peritonsillar abscesses. Eur J Clin Microbiol Infect Dis 30:619–627
9. Klug TE, Henriksen JJ, Rusan M, Fuursted K, Krogfelt KA, Ovesen T, Struve C (2014) Antibody development to Fusobacterium necrophorum in patients with peritonsillar abscess. Eur J Clin Microbiol Infect Dis 33:1733–1739. doi:10.1007/s10096-014-2130-y
10. Scottish Intercollegiate Guidelines Network (SIGN) (2014) Critical appraisal: notes and checklists. Available online at: http://www.sign.ac.uk/methodology/checklists.html
11. Aliyu SH, Marriott RK, Curran MD, Parmar S, Bentley N, Brown NM, Brazier JS, Ludlam H (2004) Real-time PCR investigation into the importance of Fusobacterium necrophorum as a cause of acute pharyngitis in general practice. J Med Microbiol 53:1029–1035
12. Jensen A, Hagelskjaer Kristensen L, Prag J (2007) Detection of Fusobacterium necrophorum subsp. funduliforme in tonsillitis in young adults by real-time PCR. Clin Microbiol Infect 13:695–701
13. Jensen A, Hansen TM, Bank S, Kristensen LH, Prag J (2015) Fusobacterium necrophorum tonsillitis: an important cause of tonsillitis in adolescents and young adults. Clin Microbiol Infect 21:266.e1–266.e3. doi:10.1016/j.cmi.2014.09.020
14. Centor RM, Atkinson TP, Ratliff AE, Xiao L, Crabb DM, Estrada CA, Faircloth MB, Oestreich L, Hatchett J, Khalife W, Waites KB (2015) The clinical presentation of Fusobacterium-positive and streptococcal-positive pharyngitis in a university health clinic: a cross-sectional study. Ann Intern Med 162:241–247
15. Kjærulff AM, Thomsen MK, Ovesen T, Klug TE (2015) Clinical and biochemical characteristics of patients with Fusobacterium necrophorum-positive acute tonsillitis. Eur Arch Otorhinolaryngol 272:1457–1463
16. Batty A, Wren MW (2005) Prevalence of Fusobacterium necrophorum and other upper respiratory tract pathogens isolated from throat swabs. Br J Biomed Sci 62:66–70
17. Amess JA, O’Neill W, Giollariabhaigh CN, Dytrych JK (2007) A six-month audit of the isolation of Fusobacterium necrophorum from patients with sore throat in a district general hospital. Br J Biomed Sci 64:63–65
18. Price SL, Hardy S, Gale P, Basten GP (2011) Prevalence of Fusobacterium necrophorum in persistent sore throat samples. Br J Biomed Sci 68:209–210
19. Eaton C, Swindells J (2014) The significance and epidemiology of Fusobacterium necrophorum in sore throats. J Infect 69:194–196
20. Ludlam H, Howard J, Kingston B, Donachie L, Foulkes J, Guha S, Curran MD (2009) Epidemiology of pharyngeal carriage of Fusobacterium necrophorum. J Med Microbiol 58:1264–1265
21. Klug TE (2014) Incidence and microbiology of peritonsillar abscess: the influence of season, age, and gender. Eur J Clin Microbiol Infect Dis 33:1163–1167. doi:10.1007/s10096-014-2052-8
22. Klug TE, Rusan M, Clemmensen KK, Fuursted K, Ovesen T (2013) Smoking promotes peritonsillar abscess. Eur Arch Otorhinolaryngol 270:3163–3167. doi:10.1007/s00405-013-2474-4
23. Fine AM, Nizet V, Mandl KD (2012) Large-scale validation of the Centor and McIsaac scores to predict group a streptococcal pharyngitis. Arch Intern Med 172:847–852
24. Klug TE, Rusan M, Fuursted K, Ovesen T (2016) Peritonsillar abscess: complication of acute tonsillitis or Weber’s glands infection? Otolaryngol Head Neck Surg 155:199–207. doi:10.1177/0194599816639551
25. Brook I (2011) The impact of smoking on oral and nasopharyngeal bacterial flora. J Dent Res 90:704–710
26. Kordeluk S, Novack L, Puterman M, Kraus M, Joshua BZ (2011) Relation between peritonsillar infection and acute tonsillitis: myth or reality? Otolaryngol Head Neck Surg 145:940–945