Evaluation of high-dose rifampin in patients with new, smear-positive tuberculosis (HIRIF): Study protocol for a randomized controlled trial

BMC Infectious Diseases

Volumn 16, Issue 1, 2016, Pages

  Milstein, Meredith ^a   Lecca, Leonid ^b,c   Peloquin, Charles ^d   Mitchison, Denis ^e   Seung, Kwonjune ^b,f   Pagano, Marcello ^g   Coleman, David ^e   Osso, Elna ^a   Coit, Julia ^a   Vargas Vasquez, Dante Elmo ^h   Sanchez Garavito, Epifanio ⁱ   Calderon, Roger ^b,c   Contreras, Carmen ^b,c   Davies, Geraint ^j   Mitnick, Carole D ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b PARTNERS IN HEALTH   (United States)

^c SOCIOS EN SALUD   (Peru)

^d UNIVERSITY OF FLORIDA   (United States)

^e ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^h Hospital Nacional Hipólito Unanue   (Peru)

ⁱ Hospital Nacional Sergio E Bernales   (Peru)

^j UNIVERSITY OF LIVERPOOL   (United Kingdom)

more..

Author keywords

Pharmacokinetics; Randomized trial; Rifampi(ci)n; Treatment shortening; Tuberculosis

Indexed keywords

ETHAMBUTOL; ISONIAZID; PYRAZINAMIDE; RIFAMPICIN; TUBERCULOSTATIC AGENT;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; DRUG SAFETY; FOLLOW UP; HUMAN; LIVER TOXICITY; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MINIMUM INHIBITORY CONCENTRATION; MULTICENTER STUDY; OUTCOME ASSESSMENT; PHASE 2 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; DOSE RESPONSE; MICROBIOLOGY; MULTICENTER STUDY (TOPIC); ORAL DRUG ADMINISTRATION; PHASE 2 CLINICAL TRIAL (TOPIC); RANDOMIZED CONTROLLED TRIAL (TOPIC); SPUTUM; TUBERCULOSIS, PULMONARY;

ADMINISTRATION, ORAL; ADULT; ANTITUBERCULAR AGENTS; CLINICAL TRIALS, PHASE II AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MULTICENTER STUDIES AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RIFAMPIN; SPUTUM; TUBERCULOSIS, PULMONARY;

EID: 84983684728     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/s12879-016-1790-x     Document Type: Article

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