Allogeneic Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe for Single-Stage Cartilage Repair in Humans upon Mixture with Recycled Autologous Chondrons

Stem Cells

Volumn 35, Issue 1, 2017, Pages 256-264

  de Windt, Tommy S ^a   Vonk, Lucienne A ^a   Slaper Cortenbach, Ineke C M ^a   van den Broek, Marcel P H ^a   Nizak, Razmara ^a   van Rijen, Mattie H P ^a   de Weger, Roel A ^a   Dhert, Wouter J A ^b   Saris, Daniel B F ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Bone marrow stromal cells; Cellular therapy; chondrons; Clinical translation; First in man; Tissue regeneration

Indexed keywords

C REACTIVE PROTEIN; COLLAGEN TYPE 2; DNA; PROTEOGLYCAN; MICROSATELLITE DNA;

ADULT; ALLOGENEIC STEM CELL TRANSPLANTATION; ARTHRALGIA; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE BIOPSY; CARTILAGE GRAFT; CHONDROPATHY; CLINICAL ARTICLE; CLINICAL OUTCOME; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRACKLE; ERYTHROCYTE SEDIMENTATION RATE; FAINTNESS; FEASIBILITY STUDY; FEMALE; HEADACHE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; JOINT INSTABILITY; JOINT SWELLING; KNEE ARTHROSCOPY; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SAFETY; PHASE 1 CLINICAL TRIAL; PHASE 2 CLINICAL TRIAL; PHYSIOTHERAPY; POSTOPERATIVE NAUSEA AND VOMITING; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SHORT TANDEM REPEAT; TISSUE REGENERATION; TISSUE REPAIR; URINE RETENTION; ARTHROSCOPY; AUTOTRANSPLANTATION; CHONDROCYTE; CLINICAL TRIAL; CYTOLOGY; DIAGNOSTIC IMAGING; GENETICS; MESENCHYMAL STROMA CELL; PATHOLOGY; PATHOPHYSIOLOGY; REGENERATION; TREATMENT OUTCOME;

ADULT; ARTHROSCOPY; CARTILAGE, ARTICULAR; CHONDROCYTES; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICROSATELLITE REPEATS; REGENERATION; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 84983667051     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2475     Document Type: Article

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