Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase

Redox Biology

Volumn 9, Issue , 2016, Pages 220-228

  Li, Chuan ^a   Zhang, Wei Jian ^a   Choi, Jaewoo ^a   Frei, Balz ^a  

^a OREGON STATE UNIVERSITY   (United States)

Author keywords

Endothelial cells; Glutathione; Oxidants; Quercetin

Indexed keywords

ASCORBIC ACID PHOSPHATASE; BUTHIONINE SULFOXIMINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; LIPOPOLYSACCHARIDE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHATASE; QUERCETIN; UNCLASSIFIED DRUG; ANTIOXIDANT; GCLC PROTEIN, HUMAN; GLUTAMATE-CYSTEINE LIGASE MODIFIER SUBUNIT, HUMAN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; OXIDIZING AGENT;

ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; INCUBATION TIME; OXIDATIVE STRESS; PRIORITY JOURNAL; UPREGULATION; AORTA; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; OXIDATION REDUCTION REACTION;

ANTIOXIDANTS; AORTA; CELLS, CULTURED; ENDOTHELIAL CELLS; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; HUMANS; LIPOPOLYSACCHARIDES; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; OXIDANTS; OXIDATION-REDUCTION; OXIDATIVE STRESS; QUERCETIN;

EID: 84983517621     PISSN: 22132317     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.redox.2016.08.012     Document Type: Article

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