Stranglehold on the spindle assembly checkpoint: The human papillomavirus E2 protein provokes BUBR1-dependent aneuploidy

Cell Cycle

Volumn 14, Issue 9, 2015, Pages 1459-1470

  Tan, Chye Ling ^a,b   Teissier, Sébastien ^a   Gunaratne, Jayantha ^c   Quek, Ling Shih ^a   Bellanger, Sophie ^a  

^a INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^b SINGAPORE GENERAL HOSPITAL   (Singapore)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

Aneuploidy; BUBR1; E2; Mitosis; P53; Papillomavirus; Spindle assembly checkpoint

Indexed keywords

BUB1 RELATED PROTEIN; CELL CYCLE PROTEIN 20; HISTONE H3; PROTEIN E2; PROTEIN E6; PROTEIN E7; PROTEIN MAD2; PROTEIN P53; UNCLASSIFIED DRUG; VIRAL PROTEIN; BUB1 PROTEIN, HUMAN; CDC20 PROTEIN, HUMAN; DNA BINDING PROTEIN; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 18; E7 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 18; MAD2L1 PROTEIN, HUMAN; ONCOGENE PROTEIN E2, HUMAN PAPILLOMAVIRUS TYPE 18; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; TP53 PROTEIN, HUMAN;

ANAPHASE; ANEUPLOIDY; ARTICLE; CELL DEATH; CONTROLLED STUDY; DNA STRAND BREAKAGE; DOWN REGULATION; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 18; KERATINOCYTE; M PHASE CELL CYCLE CHECKPOINT; MITOSIS; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HELA CELL LINE; HOST PATHOGEN INTERACTION; METABOLISM; PAPILLOMAVIRUS INFECTION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPINDLE APPARATUS; TIME FACTOR; UTERINE CERVIX TUMOR; VIROLOGY;

ANEUPLOIDY; CDC20 PROTEINS; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HELA CELLS; HOST-PATHOGEN INTERACTIONS; HUMAN PAPILLOMAVIRUS 18; HUMANS; KERATINOCYTES; M PHASE CELL CYCLE CHECKPOINTS; MAD2 PROTEINS; ONCOGENE PROTEINS, VIRAL; PAPILLOMAVIRUS INFECTIONS; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPINDLE APPARATUS; TIME FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

EID: 84983514217     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.1080/15384101.2015.1021519     Document Type: Article

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