Activation of IL-8 via PI3K/AKT-dependent pathway is involved in leptin-mediated epithelial-mesenchymal transition in human breast cancer cells

Cancer Biology and Therapy

Volumn 16, Issue 8, 2015, Pages 1220-1230

  Wang, Lin ^a   Tang, Cuiping ^a   Cao, Hong ^a   Li, Kuangfa ^a   Pang, Xueli ^a   Zhong, Liang ^a   Dang, Weiqi ^a   Tang, Hao ^a   Huang, Yunxiu ^a   Wei, Lan ^a   Su, Min ^a   Chen, Tingmei ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; EMT; IL 8; Leptin; PI3K Akt

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BIOLOGICAL MARKER; INTERLEUKIN 8; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; UVOMORULIN; VIMENTIN; LEPTIN RECEPTOR, HUMAN; STAT3 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOMA; CANCER GROWTH; CANCER PROGNOSIS; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; LYMPH NODE METASTASIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; BREAST TUMOR; CELL MOTION; DRUG EFFECTS; GENETICS; MCF-7 CELL LINE; METABOLISM; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; HUMANS; INTERLEUKIN-8; LEPTIN; MCF-7 CELLS; MICE, NUDE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, LEPTIN; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84983509016     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.1080/15384047.2015.1056409     Document Type: Article

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