Novel cationic peptide TP359 down-regulates the expression of outer membrane biogenesis genes in Pseudomonas aeruginosa: A potential TP359 anti-microbial mechanism

BMC Microbiology

Volumn 16, Issue 1, 2016, Pages

  Dosunmu, Ejovwoke F ^a   Chaudhari, Atul A ^a   Bawage, Swapnil ^a   Bakeer, Mona K ^b   Owen, Donald R ^c   Singh, Shree R ^a   Dennis, Vida A ^a   Pillai, Shreekumar R ^a  

^a ALABAMA STATE UNIVERSITY   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c Therapeutic Peptides Inc   (United States)

Author keywords

Antimicrobial effect; Antimicrobial peptides; Pseudomonas aeruginosa

Indexed keywords

ANTIMICROBIAL CATIONIC PEPTIDE; MEMBRANE PROTEIN; POLYPEPTIDE ANTIBIOTIC AGENT; PORIN; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; OPRF PROTEIN, PSEUDOMONAS AERUGINOSA; OUTER MEMBRANE PROTEIN;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL COUNT; BACTERIAL STRAIN; BACTERIUM CULTURE; BIOGENESIS; CELL DEATH; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; DRUG MECHANISM; ELECTRON MICROSCOPY; EPITHELIUM CELL; GENE EXPRESSION; MACROPHAGE; MEMBRANE DAMAGE; MEMBRANE DEPOLARIZATION; NONHUMAN; OUTER MEMBRANE; PSEUDOMONAS AERUGINOSA; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY; A-549 CELL LINE; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MICROBIAL SENSITIVITY TEST; MOUSE;

A549 CELLS; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; CELL LINE; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; DOWN-REGULATION; HUMANS; MACROPHAGES; MICE; MICROBIAL SENSITIVITY TESTS; PORINS; PSEUDOMONAS AERUGINOSA;

EID: 84983283339     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/s12866-016-0808-2     Document Type: Article

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