A selective V1A receptor agonist, selepressin, is superior to arginine vasopressin and to norepinephrine in ovine septic shock

Critical Care Medicine

Volumn 44, Issue 1, 2016, Pages 23-31

  He, Xinrong ^a,b   Su, Fuhong ^a   Taccone, Fabio Silvio ^a   Laporte, RéGent ^c   Kjølbye, Anne Louise ^c   Zhang, Jing ^d   Xie, Keliang ^a   Moussa, Mouhamed Djahoum ^a   Reinheimer, Torsten Michael ^c   Vincent, Jean Louis ^a  

^a ERASME HOSPITAL   (Belgium)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c Ferring Pharmaceuticals AS   (Denmark)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

hemodynamics; septic; shock; survival rate; vasopressor agents

Indexed keywords

ARGIPRESSIN; INTERLEUKIN 6; LACTIC ACID; NITRATE; NITRITE; NORADRENALIN; SELEPRESSIN; VASOPRESSIN V1A RECEPTOR; VASOCONSTRICTOR AGENT; VASOPRESSIN DERIVATIVE; VASOPRESSIN RECEPTOR; VASOPRESSIN, PHE(2)-ILE(3)-HGN(4)-ORN(IPR)(8)-;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRY WEIGHT; EARLY INTERVENTION; EXPERIMENTAL SHEEP; FEMALE; FLUID BALANCE; FLUID RESUSCITATION; HEART INDEX; HEMODYNAMICS; KIDNEY BLOOD FLOW; LACTATE BLOOD LEVEL; LUNG ARTERY PRESSURE; LUNG EDEMA; LUNG VASCULAR RESISTANCE; LUNG WEIGHT; MEAN ARTERIAL PRESSURE; MESENTERY BLOOD FLOW; NONHUMAN; OXYGEN CONSUMPTION; PARTIAL THROMBOPLASTIN TIME; PERITONITIS; PRIORITY JOURNAL; PROTHROMBIN TIME; REGIONAL PERFUSION; SEPTIC SHOCK; SURVIVAL TIME; URINE VOLUME; AGONISTS; ANIMAL; COMPARATIVE STUDY; RANDOMIZATION; SHEEP; SHEEP DISEASES; SHOCK, SEPTIC; VETERINARY;

ANIMALS; ARGININE VASOPRESSIN; FEMALE; NOREPINEPHRINE; RANDOM ALLOCATION; RECEPTORS, VASOPRESSIN; SHEEP; SHEEP DISEASES; SHOCK, SEPTIC; VASOCONSTRICTOR AGENTS; VASOPRESSINS;

EID: 84983151080     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001380     Document Type: Article

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