Intracellular retention of thyroglobulin in the absence of the low-density lipoprotein receptor-associated protein (RAP) is likely due to premature binding to megalin in the biosynthetic pathway

Journal of Endocrinological Investigation

Volumn 39, Issue 9, 2016, Pages 1039-1044

  Lisi, S ^a,b   Botta, R ^a,c   Rotondo Dottore, G ^a   Leo, M ^a   Latrofa, F ^a   Vitti, P ^a   Marino M ^a  

^a UNIVERSITY HOSPITAL OF PISA   (Italy)

^b SCUOLA NORMALE SUPERIORE   (Italy)

^c Diasorin SpA   (Italy)

Author keywords

LDL receptor associated protein; Megalin; RAP; Thyroglobulin; Thyroid

Indexed keywords

LOW DENSITY LIPOPROTEIN RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR ASSOCIATED PROTEIN; MEGALIN; THYROGLOBULIN; THYROTROPIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN ASSOCIATED PROTEIN; PROTEIN BINDING;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; BIOSYNTHESIS; CELL INTERACTION; COS 7 CELL LINE; EPITHELIUM CELL; FEMALE; GENETIC TRANSFECTION; HUMAN; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BINDING; THYROID CELL; WESTERN BLOTTING; ANIMAL; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BIOMARKERS; BIOSYNTHETIC PATHWAYS; BLOTTING, WESTERN; FEMALE; HUMANS; LDL-RECEPTOR RELATED PROTEIN-ASSOCIATED PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-2; MALE; MICE; MICE, KNOCKOUT; PROTEIN BINDING; THYROGLOBULIN;

EID: 84983035667     PISSN: 03914097     EISSN: 17208386     Source Type: Journal    
DOI: 10.1007/s40618-016-0464-2     Document Type: Article

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