Sputum is a surrogate for bronchoalveolar lavage for monitoring Mycobacterium tuberculosis transcriptional profiles in TB patients

Tuberculosis

Volumn 100, Issue , 2016, Pages 89-94

  Garcia, Benjamin J ^a,b   Loxton, Andre G ^c   Dolganov, Gregory M ^d   Van, Tran T ^d   Davis, J Lucian ^e,f   de Jong, Bouke C ^g   Voskuil, Martin I ^h   Leach, Sonia M ^a,b   Schoolnik, Gary K ^d   Walzl, Gerhard ^c   Strong, Michael ^a,b   Walter, Nicholas D ^a,h,i  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c STELLENBOSCH UNIVERSITY   (South Africa)

^d STANFORD UNIVERSITY   (United States)

^e YALE UNIVERSITY   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^h UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

ⁱ VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

*Gene expression profiling; Bronchoalveolar lavage microbiology; Computational biology methods; Mycobacterium tuberculosis genetics; Mycobacterium tuberculosis physiology; Sputum microbiology; Tuberculosis, pulmonary epidemiology *microbiology

Indexed keywords

BACTERIAL PROTEIN; BACTERIAL RNA; GAMMA INTERFERON; INTERLEUKIN 13; INTERLEUKIN 18; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; NITRIC OXIDE; OXYGEN; RIBOSOME PROTEIN; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TRANSCRIPTOME; DOSR PROTEIN, MYCOBACTERIUM TUBERCULOSIS; PROTEIN KINASE; TUBERCULOSTATIC AGENT;

ADULT; ARTICLE; BACTERIAL GROWTH; BACTERIAL IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; LUNG; LUNG GRANULOMA; LUNG LAVAGE; LUNG TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXYGEN CONCENTRATION; PRIORITY JOURNAL; REGULON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTH AFRICAN; SPUTUM; TRANSCRIPTOMICS; BACTERIAL GENE; BRONCHOALVEOLAR LAVAGE FLUID; COMPARATIVE STUDY; DRUG EFFECTS; DRUG MONITORING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PROCEDURES; SPECIMEN HANDLING;

ADULT; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; BRONCHOALVEOLAR LAVAGE FLUID; DRUG MONITORING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; HUMANS; MYCOBACTERIUM TUBERCULOSIS; PROTEIN KINASES; RNA, BACTERIAL; RNA, MESSENGER; SPECIMEN HANDLING; SPUTUM; TRANSCRIPTION, GENETIC; TUBERCULOSIS, PULMONARY;

EID: 84982830399     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2016.07.004     Document Type: Article

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