Resting-state Network-specific Breakdown of Functional Connectivity during Ketamine Alteration of Consciousness in Volunteers

Anesthesiology

Volumn 125, Issue 5, 2016, Pages 873-888

  Bonhomme, Vincent ^a,b   Vanhaudenhuyse, Audrey ^b,c   Demertzi, Athena ^b,c,f   Bruno, Marie Aurélie ^b,c   Jaquet, Oceane ^a,b   Bahri, Mohamed Ali ^b,c   Plenevaux, Alain ^c   Boly, Melanie ^d   Boveroux, Pierre ^b,e   Soddu, Andrea ^c,e   Brichant, Jean François ^b   Maquet, Pierre ^b,c   Laureys, Steven ^b,c  

^a Centre Hospitalier Regional de La Citadelle   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e UNIVERSITY OF WESTERN ONTARIO   (Canada)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALIZAPRIDE; KETAMINE; ONDANSETRON; ANESTHETIC AGENT;

ADULT; AGITATION; ANESTHESIA LEVEL; ARTICLE; ASSOCIATION CORTEX; BOLD SIGNAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONSCIOUSNESS; DRUG BLOOD LEVEL; ELECTROENCEPHALOGRAM; EXECUTIVE FUNCTION; FEMALE; FUNCTIONAL CONNECTIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; INSULA; MALE; MEDIAL PREFRONTAL CORTEX; NAUSEA; NUCLEAR MAGNETIC RESONANCE SCANNER; PARIETAL OPERCULUM; PARS TRIANGULARIS; POSTERIOR CINGULATE; PRECUNEUS; PREMOTOR CORTEX; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; RESTING STATE NETWORK; SEDATION; SENSORY CORTEX; SUPERIOR TEMPORAL GYRUS; SUPRAMARGINAL GYRUS; BRAIN; DIAGNOSTIC IMAGING; DRUG EFFECTS; IMAGE PROCESSING; NERVE CELL NETWORK; NUCLEAR MAGNETIC RESONANCE IMAGING; REFERENCE VALUE; REST; YOUNG ADULT;

ADULT; ANESTHETICS, DISSOCIATIVE; BRAIN; CONSCIOUSNESS; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KETAMINE; MAGNETIC RESONANCE IMAGING; MALE; NERVE NET; REFERENCE VALUES; REST; YOUNG ADULT;

EID: 84982803624     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0000000000001275     Document Type: Article

References (48)

1. Bonhomme V, Boveroux P, Brichant JF, Laureys S, Boly M: Neural correlates of consciousness during general anesthesia using functional magnetic resonance imaging (fMRI). Arch Ital Biol 2012; 150:155-63
2. Pattinson KT: Functional magnetic resonance imaging in anaesthesia research. Br J Anaesth 2013; 111:872-6
3. Friston K, Moran R, Seth AK: Analysing connectivity with Granger causality and dynamic causal modelling. Curr Opin Neurobiol 2013; 23:172-8
4. Guldenmund P, Demertzi A, Boveroux P, Boly M, Vanhaudenhuyse A, Bruno MA, Gosseries O, Noirhomme Q, Brichant JF, Bonhomme V, Laureys S, Soddu A: Thalamus, brainstem and salience network connectivity changes during propofol-induced sedation and unconsciousness. Brain Connect 2013; 3:273-85
5. Lee H, Mashour GA, Noh GJ, Kim S, Lee U: Reconfguration of network hub structure after propofol-induced unconsciousness. ANESTHESIOLOGY 2013; 119:1347-59
6. Ku SW, Lee U, Noh GJ, Jun IG, Mashour GA: Preferential inhibition of frontal-to-parietal feedback connectivity is a neurophysiologic correlate of general anesthesia in surgical patients. PLoS One 2011; 6:e25155
7. Amico e, Gomez F, Di Perri C, Vanhaudenhuyse A, Lesenfants D, Boveroux P, Bonhomme V, Brichant JF, Marinazzo D, Laureys S: Posterior cingulate cortex-related co-activation patterns: A resting state FMRI study in propofol-induced loss of consciousness. PLoS One 2014; 9:e100012
8. Jordan D, Ilg R, Riedl V, Schorer A, Grimberg S, Neufang S, Omerovic A, Berger S, Untergehrer G, Preibisch C, Schulz e, Schuster T, Schröter M, Spoormaker V, Zimmer C, Hemmer B, Wohlschläger A, Kochs eF, Schneider G: Simultaneous electroencephalographic and functional magnetic resonance imaging indicate impaired cortical top-down processing in association with anesthetic-induced unconsciousness. ANESTHESIOLOGY 2013; 119:1031-42
9. Hudetz AG: General anesthesia and human brain connectivity. Brain Connect 2012; 2:291-302
10. Boveroux P, Vanhaudenhuyse A, Bruno MA, Noirhomme Q, Lauwick S, Luxen A, Degueldre C, Plenevaux A, Schnakers C, Phillips C, Brichant JF, Bonhomme V, Maquet P, Greicius MD, Laureys S, Boly M: Breakdown of within- and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness. ANESTHESIOLOGY 2010; 113:1038-53
11. Buckner RL, Andrews-Hanna JR, Schacter DL: The brain's default network: Anatomy, function, and relevance to disease. Ann Ny Acad Sci 2008; 1124:1-38
12. Damoiseaux JS, Rombouts SA, Barkhof F, Scheltens P, Stam CJ, Smith SM, Beckmann CF: Consistent resting-state networks across healthy subjects. Proc Natl Acad Sci USA 2006; 103:13848-53
13. Laird AR, Fox PM, eickhoff SB, Turner JA, Ray KL, McKay DR, Glahn DC, Beckmann CF, Smith SM, Fox PT: Behavioral interpretations of intrinsic connectivity networks. J Cogn Neurosci 2011; 23:4022-37
14. Shackman AJ, Salomons TV, Slagter HA, Fox AS, Winter JJ, Davidson RJ: The integration of negative affect, pain and cognitive control in the cingulate cortex. Nat Rev Neurosci 2011; 12:154-67
15. Boly M, Moran R, Murphy M, Boveroux P, Bruno MA, Noirhomme Q, Ledoux D, Bonhomme V, Brichant JF, Tononi G, Laureys S, Friston K: Connectivity changes underlying spectral eeG changes during propofol-induced loss of consciousness. J Neurosci 2012; 32:7082-90
16. Vanhaudenhuyse A, Demertzi A, Schabus M, Noirhomme Q, Bredart S, Boly M, Phillips C, Soddu A, Luxen A, Moonen G, Laureys S: Two distinct neuronal networks mediate the awareness of environment and of self. J Cogn Neurosci 2011; 23:570-8
17. Sleigh J, Harvey M, Voss L, Denny B: Ketamine-More mechanisms of action than just NMDA blockade. Trends Anaesth Crit Care 2014; 4:76-81
18. Liao y, Tang J, Fornito A, Liu T, Chen X, Chen H, Xiang X, Wang X, Hao W: Alterations in regional homogeneity of resting-state brain activity in ketamine addicts. Neurosci Lett 2012; 522:36-40
19. Scheidegger M, Walter M, Lehmann M, Metzger C, Grimm S, Boeker H, Boesiger P, Henning A, Seifritz e: Ketamine decreases resting state functional network connectivity in healthy subjects: Implications for antidepressant drug action. PLoS One 2012; 7:e44799
20. Niesters M, Khalili-Mahani N, Martini C, Aarts L, van Gerven J, van Buchem MA, Dahan A, Rombouts S: effect of subanesthetic ketamine on intrinsic functional brain connectivity: A placebo-controlled functional magnetic resonance imaging study in healthy male volunteers. ANESTHESIOLOGY 2012; 117:868-77
21. Driesen NR, McCarthy G, Bhagwagar Z, Bloch M, Calhoun V, D'Souza DC, Gueorguieva R, He G, Ramachandran R, Suckow RF, Anticevic A, Morgan PT, Krystal JH: Relationship of resting brain hyperconnectivity and schizophrenia-like symptoms produced by the NMDA receptor antagonist ket-amine in humans. Mol Psychiatry 2013; 18:1199-204
22. Driesen NR, McCarthy G, Bhagwagar Z, Bloch MH, Calhoun VD, D'Souza DC, Gueorguieva R, He G, Leung HC, Ramani R, Anticevic A, Suckow RF, Morgan PT, Krystal JH: The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity. Neuropsychopharmacology 2013; 38:2613-22
23. Lee U, Ku S, Noh G, Baek S, Choi B, Mashour GA: Disruption of frontal-parietal communication by ketamine, propofol, and sevofurane. ANESTHESIOLOGY 2013; 118:1264-75
24. Blain-Moraes S, Lee U, Ku S, Noh G, Mashour GA: electroencephalographic effects of ketamine on power, cross-frequency coupling, and connectivity in the alpha bandwidth. Front Syst Neurosci 2014; 8:114
25. Domino eF, Zsigmond eK, Domino Le, Domino Ke, Kothary SP, Domino Se: Plasma levels of ketamine and two of its metabolites in surgical patients using a gas chromatographic mass fragmentographic assay. Anesth Analg 1982; 61:87-92
26. Absalom AR, Lee M, Menon DK, Sharar SR, De Smet T, Halliday J, Ogden M, Corlett P, Honey GD, Fletcher PC: Predictive performance of the Domino, Hijazi, and Clements models during low-dose target-controlled ketamine infusions in healthy volunteers. Br J Anaesth 2007; 98:615-23
27. Ramsay MA, Savege TM, Simpson BR, Goodwin R: Controlled sedation with alphaxalone-alphadolone. Br Med J 1974; 2:656-9
28. Malviya S, Voepel-Lewis T, Tait AR, Merkel S, Tremper K, Naughton N: Depth of sedation in children undergoing computed tomography: Validity and reliability of the University of Michigan Sedation Scale (UMSS). Br J Anaesth 2002; 88:241-5
29. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van essen DC, Raichle Me: The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci USA 2005; 102:9673-8
30. Raichle Me: The restless brain. Brain Connect 2011; 1:3-12
31. Fair DA, Cohen AL, Power JD, Dosenbach NU, Church JA, Miezin FM, Schlaggar BL, Petersen Se: Functional brain networks develop from a "local to distributed" organization. PLoS Comput Biol 2009; 5:e1000381
32. Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD: Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 2007; 27:2349-56
33. Maudoux A, Lefebvre P, Cabay Je, Demertzi A, Vanhaudenhuyse A, Laureys S, Soddu A: Auditory resting-state network connectivity in tinnitus: A functional MRI study. PLoS One 2012; 7:e36222
34. De Luca M, Beckmann CF, De Stefano N, Matthews PM, Smith SM: fMRI resting state networks defne distinct modes of long-distance interactions in the human brain. Neuroimage 2006; 29:1359-67
35. Demertzi A, Antonopoulos G, Heine L, Voss HU, Crone JS, de Los Angeles C, Bahri MA, Di Perri C, Vanhaudenhuyse A, Charland-Verville V, Kronbichler M, Trinka e, Phillips C, Gomez F, Tshibanda L, Soddu A, Schiff ND, Whitfeld-Gabrieli S, Laureys S: Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients. Brain 2015; 138(pt 9):2619-31
36. Ferrer-Allado T, Brechner VL, Dymond A, Cozen H, Crandall P: Ketamine-induced electroconvulsive phenomena in the human limbic and thalamic regions. ANESTHESIOLOGY 1973; 38:333-44
37. Höfich A, Hahn A, Küblböck M, Kranz GS, Vanicek T, Windischberger C, Saria A, Kasper S, Winkler D, Lanzenberger R: Ketamine-induced modulation of the thalamo-cortical network in healthy volunteers as a model for schizophrenia. Int J Neuropsychopharmacol 2015; 18
38. Alkire MT, Haier RJ, Fallon JH: Toward a unifed theory of narcosis: Brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness. Conscious Cogn 2000; 9:370-86
39. Sarasso S, Boly M, Napolitani M, Gosseries O, Charland-Verville V, Casarotto S, Rosanova M, Casali AG, Brichant JF, Boveroux P, Rex S, Tononi G, Laureys S, Massimini M: Consciousness and complexity during unresponsiveness induced by propofol, xenon, and ketamine. Curr Biol 2015; 25:3099-105
40. Schroeder Ke, Irwin ZT, Gaidica M, Bentley JN, Patil PG, Mashour GA, Chestek CA: Disruption of corticocortical information transfer during ketamine anesthesia in the primate brain. Neuroimage 2016; 134:459-65
41. Thirion B, Pinel P, Mériaux S, Roche A, Dehaene S, Poline JB: Analysis of a large fMRI cohort: Statistical and methodological issues for group analyses. Neuroimage 2007; 35:105-20
42. Barttfeld P, Uhrig L, Sitt JD, Sigman M, Jarraya B, Dehaene S: Signature of consciousness in the dynamics of resting-state brain activity. Proc Natl Acad Sci USA 2015; 112:887-92
43. Smith DV, Utevsky AV, Bland AR, Clement N, Clithero JA, Harsch Ae, McKell Carter R, Huettel SA: Characterizing individual differences in functional connectivity using dual-regression and seed-based approaches. Neuroimage 2014; 95:1-12
44. Cole DM, Smith SM, Beckmann CF: Advances and pitfalls in the analysis and interpretation of resting-state FMRI data. Front Syst Neurosci 2010; 4:8
45. Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD: Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci 2007; 27:2349-56
46. Parashchanka A, Schelfout S, Coppens M: Role of novel drugs in sedation outside the operating room: Dexmedetomidine, ketamine and remifentanil. Curr Opin Anaesthesiol 2014; 27:442-7
47. Långsjö JW, Maksimow A, Salmi e, Kaisti K, Aalto S, Oikonen V, Hinkka S, Aantaa R, Sipilä H, Viljanen T, Parkkola R, Scheinin H: S-ketamine anesthesia increases cerebral blood fow in excess of the metabolic needs in humans. ANESTHESIOLOGY 2005; 103:258-68
48. Schmidt A, Ryding e, Akeson J: Racemic ketamine does not abolish cerebrovascular autoregulation in the pig. Acta Anaesthesiol Scand 2003; 47:569-75