Electroencephalographic effects of ketamine on power, cross-frequency coupling, and connectivity in the alpha bandwidth

Frontiers in Systems Neuroscience

Volumn 8, Issue JULY, 2014, Pages

  Blain Moraes, Stefanie ^a   Lee, UnCheol ^a   Ku, SeungWoo ^b   Noh, GyuJeong ^b   Mashour, George A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Anesthetic mechanisms; Anesthetic induced unconsciousness; Consciousness; General anesthesia; Ketamine

Indexed keywords

4 AMINOBUTYRIC ACID; KETAMINE;

ADULT; ALPHA RHYTHM; ARTICLE; BRAIN FUNCTION; CLINICAL ARTICLE; CONNECTOME; CONSCIOUSNESS; CROSS FREQUENCY COUPLING; DEFAULT MODE NETWORK; ELECTROENCEPHALOGRAPHY; FEMALE; FRONTAL CORTEX; HUMAN; MALE; NERVE CELL NETWORK; NEUROPSYCHOLOGICAL TEST; OSCILLATION; PARIETAL LOBE; PHASE LAG INDEX; SIGNAL PROCESSING; SPECTROSCOPY; UNCONSCIOUSNESS;

EID: 84903724778     PISSN: 16625137     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnsys.2014.00114     Document Type: Article

References (41)

1. Barrett, A. B., Murphy, M., Bruno, M.-A., Noirhomme, Q., Boly, M., Laureys, S., et al. (2012). Granger causality analysis of steady-state electroencephalographic signals during propofol-induced anaesthesia. PLoS ONE 7:e29072. doi: 10.1371/journal.pone.0029072
2. Boly, M., Balteau, E., Schnakers, C., Degueldre, C., Moonen, G., Luxen, A., et al. (2007). Baseline brain activity fluctuations predict somatosensory perception in humans. Proc. Natl. Acad. Sci. U.S.A. 104, 12187-12192. doi: 10.1073/pnas.0611404104
3. Boly, M., Moran, R., Murphy, M., Boveroux, P., Bruno, M.-A., Noirhomme, Q., et al. (2012). Connectivity changes underlying spectral EEG changes during propofol-induced loss of consciousness. J. Neurosci. 32, 7082-7090. doi: 10.1523/JNEUROSCI.3769-11.2012
4. Boveroux, P., Vanhaudenhuyse, A., Bruno, M.-A., Noirhomme, Q., Lauwick, S., Luxen, A., et al. (2010). Breakdown of within-and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness. Anesthesiology 113, 1038-1053. doi: 10.1097/ALN.0b013e3181f697f5
5. Canolty, R. T., Edwards, E., Dalal, S. S., Soltani, M., Nagarajan, S. S., Kirsch, H. E., et al. (2006). High gamma power is phase-locked to theta oscillations in human neocortex. Science 313, 1626-1628. doi: 10.1126/science.1128115
6. Chen, X., Shu, S., and Bayliss, D. A. (2009). HCN1 channel subunits are a molecular substrate for hypnotic actions of ketamine. J. Neurosci. 29, 600-609. doi: 10.1523/JNEUROSCI.3481-08.2009
7. Ching, S., and Brown, E. N. (2014). Modeling the dynamical effects of anesthesia on brain circuits. Curr. Opin. Neurobiol. 25, 116-122. doi: 10.1016/j.conb.2013.12.011
8. Ching, S., Cimenser, A., Purdon, P. L., Brown, E. N., and Kopell, N. J. (2010). Thalamocortical model for a propofol-induced α-rhythm associated with loss of consciousness. Proc. Natl. Acad. Sci. U.S.A. 107, 22665-22670. doi: 10.1073/pnas.1017069108
9. Corssen, G., and Domino, E. F. (1966). Dissociative anesthesia: further pharmacologic studies and first clinical experience with the phencyclidine derivative CI-581. Anesth. Analg. 45, 29-40.
10. Dehaene, S., and Changeux, J.-P. (2011). Experimental and theoretical approaches to conscious processing. Neuron 70, 200-227. doi: 10.1016/j.neuron.2011.03.018
11. Delorme, A., and Makeig, S. (2004). EEGLAB: an open source toolbox for analysis of single-trial EEG dynamics including independent component analysis. J. Neurosci. Methods 134, 9-21. doi: 10.1016/j.jneumeth.2003.10.009
12. Demertzi, A., Soddu, A., and Laureys, S. (2013). Consciousness supporting networks. Curr. Opin. Neurobiol. 23, 239-211. doi: 10.1016/j.conb.2012.12.003
13. Feshchenko, V. A., Veselis, R. A., and Reinsel, R. A. (2004). Propofol-induced alpha rhythm. Neuropsychobiology 50, 257-266. doi: 10.1159/000079981
14. Grace, R. F. (2003). The effect of variable-dose diazepam on dreaming and emergence phenomena in 400 cases of ketamine-fentanyl anaesthesia. Anaesthesia 58, 904-910. doi: 10.1046/j.1365-2044.2003.03341.x
15. Imas, O. A., Ropella, K. M., Ward, B. D., Wood, J. D., and Hudetz, A. G. (2005). Volatile anesthetics disrupt frontal-posterior recurrent information transfer at gamma frequencies in rat. Neurosci. Lett. 387, 145-150. doi: 10.1016/j.neulet.2005.06.018
16. Jordan, D., Ilg, R., Riedl, V., Schorer, A., Grimberg, S., Neufang, S., et al. (2013). Simultaneous electroencephalographic and functional magnetic resonance imaging indicate impaired cortical top-down processing in association with anesthetic-induced unconsciousness. Anesthesiology 119, 1031-1042. doi: 10.1097/ALN.0b013e3182a7ca92
17. Kikuchi, T., Wang, Y., Shinbori, H., Sato, K., and Okumura, F. (1997). Effects of ketamine and pentobarbitone on acetylcholine release from the rat frontal cortex in vivo. Br. J. Anaesth. 79, 128-130.
18. Ku, S.-W., Lee, U., Noh, G.-J., Jun, I.-G., and Mashour, G. A. (2011). Preferential inhibition of frontal-to-parietal feedback connectivity is a neurophysiologic correlate of general anesthesia in surgical patients. PLoS ONE 6:e25155. doi: 10.1371/journal.pone.0025155
19. Kushikata, T., Yoshida, H., Kudo, M., Kudo, T., Kudo, T., and Hirota, K. (2011). Role of coerulean noradrenergic neurones in general anaesthesia in rats. Br. J. Anaesth. 107, 924-929. doi: 10.1093/bja/aer303
20. Långsjö, J. W., Maksimow, A., Salmi, E., Kaisti, K., Aalto, S., Oikonen, V., et al. (2005). S-ketamine anesthesia increases cerebral blood flow in excess of the metabolic needs in humans. Anesthesiology 103, 258-268. doi: 10.1097/00000542-200508000-00008
21. Lee, H., Mashour, G. A., Noh, G.-J., Kim, S., and Lee, U. (2013a). Reconfiguration of network hub structure after propofol-induced unconsciousness. Anesthesiology 119, 1347-1359. doi: 10.1097/ALN.0b013e3182a8ec8c
22. Lee, U., Kim, S., Noh, G.-J., Choi, B.-M., Hwang, E., and Mashour, G. A. (2009). The directionality and functional organization of frontoparietal connectivity during consciousness and anesthesia in humans. Conscious. Cogn. 18, 1069-1078. doi: 10.1016/j.concog.2009.04.004
23. Lee, U., Ku, S., Noh, G., Baek, S., Choi, B., and Mashour, G. A. (2013b). Disruption of frontal-parietal communication by ketamine, propofol, and sevoflurane. Anesthesiology 118, 1264-1275. doi: 10.1097/ALN.0b013e31829103f5
24. Leslie, K., Skrzypek, H., Paech, M., Kurowski, I., and Whybrow, T. (2007). Dreaming during anesthesia and anesthetic depth in elective surgery patients: a prospective cohort study. Anesthesiology 106, 33-42. doi: 10.1097/00000542-200701000-00010
25. Lu, J., Nelson, L. E., Franks, N., Maze, M., Chamberlin, N. L., and Saper, C. B. (2008). Role of endogenous sleep-wake and analgesic systems in anesthesia. J. Comp. Neurol. 508, 648-662. doi: 10.1002/cne.21685
26. Maksimow, A., Särkelä, M., Långsjö, J. W., Salmi, E., Kaisti, K. K., Yli-Hankala, A., et al. (2006). Increase in high frequency EEG activity explains the poor performance of EEG spectral entropy monitor during S-ketamine anesthesia. Clin. Neurophysiol. 117, 1660-1668. doi: 10.1016/j.clinph.2006.05.011
27. Miyakoshi, M., Delorme, A., Mullen, T., Kojima, K., Makeig, S., and Asano, E. (2013). Automated detection of cross-frequency coupling in the electrocorticogram for clinical inspection. Conf. Proc. IEEE Eng. Med. Biol. Soc. 2013, 3282-3285. doi: 10.1109/EMBC.2013.6610242
28. Mukamel, E. A., Pirondini, E., Babadi, B., Wong, K. F. K., Pierce, E. T., Harrell, P. G., et al. (2014). A transition in brain state during propofol-induced unconsciousness. J. Neurosci. 34, 839-845. doi: 10.1523/JNEUROSCI.5813-12.2014
29. Murphy, M., Bruno, M.-A., Riedner, B. A., Boveroux, P., Noirhomme, Q., Landsness, E. C., et al. (2011). Propofol anesthesia and sleep: a high-density EEG study. Sleep 34, 283-291.
30. Purdon, P. L., Pierce, E. T., Mukamel, E. A., Prerau, M. J., Walsh, J. L., Wong, K. F. K., et al. (2013). Electroencephalogram signatures of loss and recovery of consciousness from propofol. Proc. Natl. Acad. Sci. U.S.A. 110, E1142-E1151. doi: 10.1073/pnas.1221180110
31. Sanders, R. D., Tononi, G., Laureys, S., and Sleigh, J. W. (2012). Unresponsiveness ≠ unconsciousness. Anesthesiology 116, 946-959. doi: 10.1097/ALN.0b013e318249d0a7
32. Schrouff, J., Perlbarg, V., Boly, M., Marrelec, G., Boveroux, P., Vanhaudenhuyse, A., et al. (2011). Brain functional integration decreases during propofol-induced loss of consciousness. Neuroimage 57, 198-205. doi: 10.1016/j.neuroimage.2011.04.020
33. Stam, C. J., Nolte, G., and Daffertshofer, A. (2007). Phase lag index: assessment of functional connectivity from multi channel EEG and MEG with diminished bias from common sources. Hum. Brain Mapp. 28, 1178-1193. doi: 10.1002/hbm.20346
34. Stam, C. J., and van Straaten, E. C. W. (2012). Go with the flow: use of a directed phase lag index (dPLI) to characterize patterns of phase relations in a large-scale model of brain dynamics. Neuroimage 62, 1415-1428. doi: 10.1016/j.neuroimage.2012.05.050
35. Supp, G. G., Siegel, M., Hipp, J. F., and Engel, A. K. (2011). Cortical hypersynchrony predicts breakdown of sensory processing during loss of consciousness. Curr. Biol. 21, 1988-1993. doi: 10.1016/j.cub.2011.10.017
36. Tononi, G. (2011). The integrated information theory of consciousness: an updated account. Arch. Ital. Biol. 150, 56-90. doi: 10.4449/aib.v149i5.1388
37. Vijayan, S., Ching, S., Purdon, P. L., Brown, E. N., and Kopell, N. J. (2013). Thalamocortical mechanisms for the anteriorization of alpha rhythms during propofol-induced unconsciousness. J. Neurosci. 33, 11070-11075. doi: 10.1523/JNEUROSCI.5670-12.2013
38. Welch, P. D. (1967). The use of fast Fourier transform for the estimation of power spectra: a method based on time averaging over short, modified periodograms. IEEE Trans. Audio Electroacoustics 15, 70-73. doi: 10.1109/TAU.1967.1161901
39. Xia, M., Wang, J., and He, Y. (2013). BrainNet Viewer: a network visualization tool for human brain connectomics. PLoS ONE 8:e68910. doi: 10.1371/journal.pone.0068910
40. Yamamura, T., Harada, K., Okamura, A., and Kemmotsu, O. (1990). Is the site of action of ketamine anesthesia the N-methyl-D-aspartate receptor? Anesthesiology 72, 704-710.
41. Zhou, C., Douglas, J. E., Kumar, N. N., Shu, S., Bayliss, D. A., and Chen, X. (2013). Forebrain HCN1 channels contribute to hypnotic actions of ketamine. Anesthesiology 118, 785-795. doi: 10.1097/ALN.0b013e318287b7c8