Rapid and Selective Detection of Pathogenic Bacteria in Bloodstream Infections with Aptamer-Based Recognition

ACS Applied Materials and Interfaces

Volumn 8, Issue 30, 2016, Pages 19371-19378

  Shen, Haijing ^a   Wang, Jie ^a   Liu, Haoyang ^a   Li, Zhihao ^a   Jiang, Fenglei ^a   Wang, Fu Bing ^a   Yuan, Quan ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

aptamer; bacteria; bloodstream infection; magnetic nanoparticle; sepsis

Indexed keywords

BACTERIOLOGY; DIAGNOSIS; NANOMAGNETICS; NANOPARTICLES;

APTAMERS; BACTERIAL IDENTIFICATIONS; BLOODSTREAM INFECTION; MAGNETIC NANO-PARTICLES; PATHOGENIC BACTERIUM; SELECTIVE DETECTION; SENSITIVE DETECTION; SEPSIS;

BACTERIA;

APTAMER;

BACTEREMIA; BACTERIUM; CATHETER INFECTION; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR DIAGNOSIS; PROCEDURES; SENSITIVITY AND SPECIFICITY;

APTAMERS, NUCLEOTIDE; BACTEREMIA; BACTERIA; BACTERIOLOGICAL TECHNIQUES; CATHETER-RELATED INFECTIONS; HUMANS; MOLECULAR DIAGNOSTIC TECHNIQUES; SENSITIVITY AND SPECIFICITY;

EID: 84982719971     PISSN: 19448244     EISSN: 19448252     Source Type: Journal    
DOI: 10.1021/acsami.6b06671     Document Type: Article

References (55)

1. Cohen, J. The Immunopathogenesis of Sepsis Nature 2002, 420, 885-891 10.1038/nature01326
2. Angus, D. C.; van der Poll, T. Severe Sepsis and Septic Shock N. Engl. J. Med. 2013, 369, 840-851 10.1056/NEJMra1208623
3. Rocheteau, P.; Chatre, L.; Briand, D.; Mebarki, M.; Jouvion, G.; Bardon, J.; Crochemore, C.; Serrani, P.; Lecci, P. P.; Latil, M.; Matot, B.; Carlier, P. G.; Latronico, N.; Huchet, C.; Lafoux, A.; Sharshar, T.; Ricchetti, M.; Chretien, F. Sepsis Induces Long-Term Metabolic and Mitochondrial Muscle Stem Cell Dysfunction Amenable by Mesenchymal Stem Cell Therapy Nat. Commun. 2015, 6, 10145 10.1038/ncomms10145
4. Hidron, A. I.; Edwards, J. R.; Patel, J.; Horan, T. C.; Sievert, D. M.; Pollock, D. A.; Fridkin, S. K. Antimicrobial-Resistant Pathogens Associated with Healthcare-Associated Infections: Annual Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007 Infect. Cont. Hosp. Ep. 2008, 29, 996-1011 10.1086/591861
5. Zhu, L. X.; Shen, D. X.; Zhou, Q. M.; Liu, C. J.; Li, Z. X.; Fang, X. D.; Li, Q. Z. Universal Probe Library Based Real-time PCR for Rapid Detection of Bacterial Pathogens from Positive Blood Culture Bottles World J. Microbiol. Biotechnol. 2014, 30, 967-975 10.1007/s11274-013-1515-x
6. Ray, P. C.; Khan, S. A.; Singh, A. K.; Senapati, D.; Fan, Z. Nanomaterials for Targeted Detection and Photothermal Killing of Bacteria Chem. Soc. Rev. 2012, 41, 3193-3209 10.1039/c2cs15340h
7. Lee, A.; Mirrett, S.; Reller, L. B.; Weinstein, M. P. Detection of Bloodstream Infections in Adults: How Many Blood Cultures Are Needed? J. Clin. Microbiol. 2007, 45, 3546-3548 10.1128/JCM.01555-07
8. Reisner, B. S.; Woods, G. L. Times to Detection of Bacteria and Yeasts in BACTEC 9240 Blood Culture Bottles J. Clin. Microbiol. 1999, 37, 2024-2026
9. Sarkar, S.; Bhagat, I.; DeCristofaro, J. D.; Wiswell, T. E.; Spitzer, A. R. A Study of the Role of Multiple Site Blood Cultures in the Evaluation of Neonatal Sepsis J. Perinatol. 2006, 26, 18-22 10.1038/sj.jp.7211410
10. Saito, T.; Aoki, Y.; Mori, Y.; Kohi, F. Blood Culture Examinations at a Community Hospital Without a Microbiology Laboratory: Using an Automated Blood Culture System and Performing a Gram Stain on Positive Culture Bottles in the Institution J. Infect. Chemother. 2004, 10, 239-241 10.1007/s10156-004-0328-0
11. Khan, S. A.; Singh, A. K.; Senapati, D.; Fan, Z.; Ray, P. C. Bio-conjugated Popcorn Shaped Gold Nanoparticles for Targeted Photothermal Killing of Multiple Drug Resistant Salmonella DT104 J. Mater. Chem. 2011, 21, 17705-17709 10.1039/c1jm13320a
12. Fan, Z.; Senapati, D.; Khan, S. A.; Singh, A. K.; Hamme, A.; Yust, B.; Sardar, D.; Ray, P. C. Popcorn-Shaped Magnetic Core-Plasmonic Shell Multifunctional Nanoparticles for the Targeted Magnetic Separation and Enrichment, Label-Free SERS Imaging, and Photothermal Destruction of Multidrug-Resistant Bacteria Chem.-Eur. J. 2013, 19, 2839-2847 10.1002/chem.201202948
13. Kavruk, M.; Celikbicak, O.; Ozalp, V. C.; Borsa, B. A.; Hernandez, F. J.; Bayramoglu, G.; Salih, B.; Arica, M. Y. Antibiotic Loaded Nanocapsules Functionalized with Aptamer Gates for Targeted Destruction of Pathogens Chem. Commun. 2015, 51, 8492-8495 10.1039/C5CC01869B
14. Boedicker, J. Q.; Li, L.; Kline, T. R.; Ismagilov, R. F. Detecting Bacteria and Determining Their Susceptibility to Antibiotics by Stochastic Confinement in Nanoliter Droplets Using Plug-based Microfluidics Lab Chip 2008, 8, 1265-1272 10.1039/b804911d
15. Yealy, D. M.; Kellum, J. A.; Huang, D. T.; Barnato, A. E.; Weissfeld, L. A.; Pike, F.; Terndrup, T.; Wang, H. E.; Hou, P. C.; LoVecchio, F.; Filbin, M. R.; Shapiro, N. I.; Angus, D. C. A Randomized Trial of Protocol-Based Care for Early Septic Shock N. Engl. J. Med. 2014, 370, 1683-1693 10.1056/NEJMoa1401602
16. Niemz, A.; Ferguson, T. M.; Boyle, D. S. Point-of-care Nucleic Acid Testing for Infectious Diseases Trends Biotechnol. 2011, 29, 240-250 10.1016/j.tibtech.2011.01.007
17. Shepard, J. R.; Addison, R. M.; Alexander, B. D.; Della-Latta, P.; Gherna, M.; Haase, G.; Hall, G.; Johnson, J. K.; Merz, W. G.; Peltroche-Llacsahuanga, H.; Stender, H.; Venezia, R. A.; Wilson, D.; Procop, G. W.; Wu, F.; Fiandaca, M. J. Multicenter Evaluation of the Candida albicans/Candida glabrata Peptide Nucleic Acid Fluorescent in situ Hybridization Method for Simultaneous Dual-Color Identification of C. albicans and C. glabrata Directly from Blood Culture Bottles J. Clin. Microbiol. 2008, 46, 50-55 10.1128/JCM.01385-07
18. Wang, P. Rapid Differentiation of Candida albicans from non-C. albicans Directly in a Variety of Clinical Specimens Using Fluorescent in situ Hybridisation Mycoses 2011, 54, 331-336 10.1111/j.1439-0507.2009.01851.x
19. Burtscher, C.; Wuertz, S. Evaluation of the Use of PCR and Reverse Transcriptase PCR for Detection of Pathogenic Bacteria in Biosolids from Anaerobic Digestors and Aerobic Composters Appl. Environ. Microb. 2003, 69, 4618-4627 10.1128/AEM.69.8.4618-4627.2003
20. Ottesen, E. A.; Hong, J. W.; Quake, S. R.; Leadbetter, J. R. Microfluidic Digital PCR Enables Multigene Analysis of Individual Environmental Bacteria Science 2006, 314, 1464-1467 10.1126/science.1131370
21. Pechorsky, A.; Nitzan, Y.; Lazarovitch, T. Identification of Pathogenic Bacteria in Blood Cultures: Comparison Between Conventional and PCR Methods J. Microbiol. Methods 2009, 78, 325-330 10.1016/j.mimet.2009.07.008
22. Zhang, L.; Xu, J. J.; Mi, L.; Gong, H.; Jiang, S. Y.; Yu, Q. M. Multifunctional Magnetic-Plasmonic Nanoparticles for Fast Concentration and Sensitive Detection of Bacteria Using SERS Biosens. Bioelectron. 2012, 31, 130-136 10.1016/j.bios.2011.10.006
23. Shi, M. L.; Zheng, J.; Tan, Y. J.; Tan, G. X.; Li, J. S.; Li, Y. H.; Li, X.; Zhou, Z. G.; Yang, R. H. Ultrasensitive Detection of Single Nucleotide Polymorphism in Human Mitochondrial DNA Utilizing Ion-Mediated Cascade Surface-Enhanced Raman Spectroscopy Amplification Anal. Chem. 2015, 87, 2734-2740 10.1021/ac504000p
24. Wang, H. Y.; Zhou, Y. F.; Jiang, X. X.; Sun, B.; Zhu, Y.; Wang, H.; Su, Y. Y.; He, Y. Simultaneous Capture, Detection, and Inactivation of Bacteria as Enabled by a Surface-Enhanced Raman Scattering Multifunctional Chip Angew. Chem., Int. Ed. 2015, 54, 5132-5136 10.1002/anie.201412294
25. Chung, H. J.; Reiner, T.; Budin, G.; Min, C.; Liong, M.; Issadore, D.; Lee, H.; Weissleder, R. Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles ACS Nano 2011, 5, 8834-8841 10.1021/nn2029692
26. Miranda, O. R.; Li, X. N.; Garcia-Gonzalez, L.; Zhu, Z. J.; Yan, B.; Bunz, U. H.; Rotello, V. M. Colorimetric Bacteria Sensing Using a Supramolecular Enzyme-Nanoparticle Biosensor J. Am. Chem. Soc. 2011, 133, 9650-9653 10.1021/ja2021729
27. Shangguan, J. F.; Li, Y. H.; He, D. G.; He, X. X.; Wang, K. M.; Zou, Z.; Shi, H. A Combination of Positive Dielectrophoresis Driven On-line Enrichment and Aptamer-Fluorescent Silica Nanoparticle Label for Rapid and Sensitive Detection of Staphylococcus aureus Analyst 2015, 140, 4489-4497 10.1039/C5AN00535C
28. Kang, D. K.; Ali, M. M.; Zhang, K. X.; Huang, S. S.; Peterson, E.; Digman, M. A.; Gratton, E.; Zhao, W. Rapid Detection of Single Bacteria in Unprocessed Blood Using Integrated Comprehensive Droplet Digital Detection Nat. Commun. 2014, 5, 5427 10.1038/ncomms6427
29. Lee, H.; Yoon, T. J.; Weissleder, R. Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System Angew. Chem., Int. Ed. 2009, 48, 5657-5660 10.1002/anie.200901791
30. Liu, J. W.; Cao, Z. H.; Lu, Y. Functional Nucleic Acid Sensors Chem. Rev. 2009, 109, 1948-1998 10.1021/cr030183i
31. Wang, J.; Shen, H. J.; Hu, X. X.; Li, Y.; Li, Z. H.; Xu, J. F.; Song, X. F.; Zeng, H. B.; Yuan, Q. A Targeted "Capture" and "Removal" Scavenger toward Multiple Pollutants for Water Remediation based on Molecular Recognition Adv. Sci. 2016, 3, 1500289 10.1002/advs.201500289
32. Zheng, J.; Bai, J. H.; Zhou, Q. F.; Li, J. S.; Li, Y. H.; Yang, J. F.; Yang, R. H. DNA-Templated in situ Growth of AgNPs on SWNTs: A New Approach for Highly Sensitive SERS Assay of microRNA Chem. Commun. 2015, 51, 6552-6555 10.1039/C5CC01003A
33. Zhu, G. Z.; Zheng, J.; Song, E. Q.; Donovan, M.; Zhang, K. J.; Liu, C.; Tan, W. H. Self-assembled, Aptamer-tethered DNA Nanotrains for Targeted Transport of Molecular Drugs in Cancer Theranostics Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 7998-8003 10.1073/pnas.1220817110
34. Guo, W.; Hong, F.; Liu, N. N.; Huang, J. Y.; Wang, B. Y.; Duan, R. X.; Lou, X. D.; Xia, F. Target-Specific 3D DNA Gatekeepers for Biomimetic Nanopores Adv. Mater. 2015, 27, 2090-2095 10.1002/adma.201405078
35. 4@Polydopamine Core Shell Nanocomposites for Intracellular mRNA Detection and Imaging-Guided Photothermal Therapy ACS Nano 2014, 8, 3876-3883 10.1021/nn500722y
36. Chen, F.; Zhou, J.; Luo, F. L.; Mohammed, A. B.; Zhang, X.-L. Aptamer from Whole-Bacterium SELEX as New Therapeutic Reagent Against Virulent Mycobacterium tuberculosis Biochem. Biophys. Res. Commun. 2007, 357, 743-748 10.1016/j.bbrc.2007.04.007
37. Zhang, C. X.; Lv, X. F.; Han, X.; Man, Y.; Saeed, Y.; Qing, H.; Deng, Y. L. Whole-Cell based Aptamer Selection for Selective Capture of Microorganisms using Microfluidic Devices Anal. Methods 2015, 7, 6339-6345 10.1039/C5AY01016K
38. Wu, S. J.; Duan, N.; Shi, Z.; Fang, C. C.; Wang, Z. P. Simultaneous Aptasensor for Multiplex Pathogenic Bacteria Detection Based on Multicolor Upconversion Nanoparticles Labels Anal. Chem. 2014, 86, 3100-3107 10.1021/ac404205c
39. Wang, J. F.; Wu, X. Z.; Wang, C. W.; Shao, N. S.; Dong, P. T.; Xiao, R.; Wang, S. Q. Magnetically Assisted Surface-Enhanced Raman Spectroscopy for the Detection of Staphylococcus aureus Based on Aptamer Recognition ACS Appl. Mater. Interfaces 2015, 7, 20919-20929 10.1021/acsami.5b06446
40. Cheng, D.; Yu, M. Q.; Fu, F.; Han, W. Y.; Li, G.; Xie, J. P.; Song, Y.; Swihart, M. T.; Song, E. Q. Dual Recognition Strategy for Specific and Sensitive Detection of Bacteria Using Aptamer-Coated Magnetic Beads and Antibiotic-Capped Gold Nanoclusters Anal. Chem. 2016, 88, 820-825 10.1021/acs.analchem.5b03320
41. Luo, C. H.; Lei, Y. N.; Yan, L.; Yu, T. X.; Li, Q.; Zhang, D. C.; Ding, S. J.; Ju, H. X. A Rapid and Sensitive Aptamer-Based Electrochemical Biosensor for Direct Detection of Escherichia ColiO111 Electroanalysis 2012, 24, 1186-1191 10.1002/elan.201100700
42. Chang, Y. C.; Yang, C. Y.; Sun, R. L.; Cheng, Y. F.; Kao, W. C.; Yang, P. C. Rapid Single Cell Detection of Staphylococcus aureus by Aptamer-Conjugated Gold Nanoparticles Sci. Rep. 2013, 3, 1863 10.1038/srep01863
43. 2 Shells for Multifunctional Core-Shell Structures J. Am. Chem. Soc. 2012, 134, 11864-11867 10.1021/ja3037146
44. Liu, J.; Sun, Z. K.; Deng, Y. H.; Zou, Y.; Li, C. Y.; Guo, X. H.; Xiong, L. Q.; Gao, Y.; Li, F. Y.; Zhao, D. Y. Highly Water-Dispersible Biocompatible Magnetite Particles with Low Cytotoxicity Stabilized by Citrate Groups Angew. Chem., Int. Ed. 2009, 48, 5875-5879 10.1002/anie.200901566
45. Yue, Q.; Li, J. L.; Luo, W.; Zhang, Y.; Elzatahry, A. A.; Wang, X. Q.; Wang, C.; Li, W.; Cheng, X. W.; Alghamdi, A.; Abdullah, A. M.; Deng, Y. H.; Zhao, D. Y. An Interface Coassembly in Biliquid Phase: Toward Core-Shell Magnetic Mesoporous Silica Microspheres with Tunable Pore Size J. Am. Chem. Soc. 2015, 137, 13282-13289 10.1021/jacs.5b05619
46. Li, W.; Deng, Y. H.; Wu, Z. X.; Qian, X. F.; Yang, J. P.; Wang, Y.; Gu, D.; Zhang, F.; Tu, B.; Zhao, D. Y. Hydrothermal Etching Assisted Crystallization: A Facile Route to Functional Yolk-Shell Titanate Microspheres with Ultrathin Nanosheets-Assembled Double Shells J. Am. Chem. Soc. 2011, 133, 15830-15833 10.1021/ja2055287
47. Deng, Y. H.; Cai, Y.; Sun, Z. K.; Zhao, D. Y. Magnetically Responsive Ordered Mesoporous Materials: A Burgeoning Family of Functional Composite Nanomaterials Chem. Phys. Lett. 2011, 510, 1-13 10.1016/j.cplett.2011.04.093
48. Neely, A.; Perry, C.; Varisli, B.; Singh, A. K.; Arbneshi, T.; Senapati, D.; Kalluri, J. R.; Ray, P. C. Ultrasensitive and Highly Selective Detection of Alzheimer's Disease Biomarker Using Two-Photon Rayleigh Scattering Properties of Gold Nanoparticle ACS Nano 2009, 3, 2834-2840 10.1021/nn900813b
49. Singh, A. K.; Senapati, D.; Wang, S. G.; Griffin, J.; Neely, A.; Candice, P.; Naylor, K. M.; Varisli, B.; Kalluri, J. R.; Ray, P. C. Gold Nanorod Based Selective Identification of Escherichia coli Bacteria Using Two-Photon Rayleigh Scattering Spectroscopy ACS Nano 2009, 3, 1906-1912 10.1021/nn9005494
50. Li, W.; Yue, Q.; Deng, Y. H.; Zhao, D. Y. Ordered Mesoporous Materials Based on Interfacial Assembly and Engineering Adv. Mater. 2013, 25, 5129-5152 10.1002/adma.201302184
51. Reasoner, D. J. Heterotrophic Plate Count Methodology in the United States Int. J. Food Microbiol. 2004, 92, 307-315 10.1016/j.ijfoodmicro.2003.08.008
52. Peñuelas-Urquides, K.; Villarreal-Treviño, L.; Silva-Ramírez, B.; Rivadeneyra-Espinoza, L.; Said-Fernández, S.; León, M. Measuring of Mycobacterium tuberculosis Growth. A Correlation of the Optical Measurements with Colony Forming Units Braz. J. Microbiol. 2013, 44, 287-290 10.1590/S1517-83822013000100042
53. Zhang, Z. H.; Liu, C. H.; Bai, J. H.; Wu, C. C.; Xiao, Y.; Li, Y. H.; Zheng, J.; Yang, R. H.; Tan, W. H. Silver Nanoparticle Gated, Mesoporous Silica Coated Gold Nanorods (AuNR@MS@AgNPs): Low Premature Release and Multifunctional Cancer Theranostic Platform ACS Appl. Mater. Interfaces 2015, 7, 6211-6219 10.1021/acsami.5b00368
54. Hans Gulliksson, H.; van der Meer, P. F. Storage of Whole Blood Overnight in Different Blood Bags Preceding Preparation of Blood Components: in vitro Effects on Red Blood Cells Blood Transfus 2009, 7, 210-215
55. Song, H.; Nor, Y. A.; Yu, M. H.; Yang, Y. N.; Zhang, J.; Zhang, H. W.; Xu, C.; Mitter, N.; Yu, C. Z. Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition J. Am. Chem. Soc. 2016, 138, 6455-6462 10.1021/jacs.6b00243