Cerebrospinal α-synuclein in α-synuclein aggregation disorders: tau/α-synuclein ratio as potential biomarker for dementia with Lewy bodies

Journal of Neurology

Volumn 263, Issue 11, 2016, Pages 2271-2277

  Llorens, Franc ^a,b   Schmitz, Matthias ^a,b   Varges, Daniela ^a   Kruse, Niels ^c   Gotzmann, Nadine ^a,b   Gmitterová, Karin ^a,d   Mollenhauer, Brit ^c,e   Zerr, Inga ^a,b  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d Physics and Informatics   (Slovakia)

^e Center of Parkinsonism and Movement Disorders   (Germany)

Author keywords

Biomarker; Cerebrospinal fluid; Neurodegenerative diseases; Synuclein; Synuclein aggregation disorders

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; TAU PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); BIOLOGICAL MARKER; PEPTIDE FRAGMENT;

AGED; ARTICLE; CONTROLLED STUDY; DEMENTIA; DIAGNOSTIC VALUE; DIFFUSE LEWY BODY DISEASE; ESSENTIAL TREMOR; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; NEUROPATHOLOGY; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN CEREBROSPINAL FLUID LEVEL; SHY DRAGER SYNDROME; CEREBROSPINAL FLUID; COMPLICATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; MALE; MIDDLE AGED; NONPARAMETRIC TEST; PROTEIN AGGREGATION, PATHOLOGICAL; RECEIVER OPERATING CHARACTERISTIC;

AGED; AMYLOID BETA-PEPTIDES; BIOMARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; LEWY BODY DISEASE; MALE; MIDDLE AGED; PEPTIDE FRAGMENTS; PROTEIN AGGREGATION, PATHOLOGICAL; ROC CURVE; STATISTICS, NONPARAMETRIC; TAU PROTEINS;

EID: 84982282603     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-016-8259-0     Document Type: Article

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