-
1
-
-
81755185429
-
Autism spectrum disorders in older adults: toward defining a research agenda
-
Piven J, Rabins P; Autism-in-Older Adults Working Group. Autism spectrum disorders in older adults: toward defining a research agenda. J Am Geriatr Soc 2011; 59: 2151-2155.
-
(2011)
J Am Geriatr Soc
, vol.59
, pp. 2151-2155
-
-
Piven, J.1
Rabins, P.2
-
2
-
-
79953863215
-
-
United Kingdom: NHS The Information Centre for Health and Social Care;
-
Brugha T, McManus S, Meltzer H, Smith J, Scott F, Purdon S, Harris J and Bankart J. Autism spectrum disorders in adults living in households throughout England-2007, report from the adult psychiatric morbidity survey. United Kingdom: NHS The Information Centre for Health and Social Care; 2009.
-
(2009)
Autism spectrum disorders in adults living in households throughout England-2007, report from the adult psychiatric morbidity survey
-
-
Brugha, T.1
McManus, S.2
Meltzer, H.3
Smith, J.4
Scott, F.5
Purdon, S.6
Harris, J.7
Bankart, J.8
-
3
-
-
4644373224
-
Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice
-
Moy SS, Nadler JJ, Perez A, Barbaro RP, Johns JM, Magnuson TR, Piven J and Crawley JN. Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice. Genes Brain Behav 2004; 3: 287-302.
-
(2004)
Genes Brain Behav
, vol.3
, pp. 287-302
-
-
Moy, S.S.1
Nadler, J.J.2
Perez, A.3
Barbaro, R.P.4
Johns, J.M.5
Magnuson, T.R.6
Piven, J.7
Crawley, J.N.8
-
4
-
-
33845284824
-
Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains
-
Moy SS, Nadler JJ, Young NB, Perez A, Holloway LP, Barbaro RP, Barbaro JR, Wilson LM, Threadgill DW, Lauder JM, Magnuson TR and Crawley JN. Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains. Behav Brain Res 2007; 176: 4-20.
-
(2007)
Behav Brain Res
, vol.176
, pp. 4-20
-
-
Moy, S.S.1
Nadler, J.J.2
Young, N.B.3
Perez, A.4
Holloway, L.P.5
Barbaro, R.P.6
Barbaro, J.R.7
Wilson, L.M.8
Threadgill, D.W.9
Lauder, J.M.10
Magnuson, T.R.11
Crawley, J.N.12
-
5
-
-
84880326065
-
The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers
-
Meyza KZ, Defensor EB, Jensen AL, Corley MJ, Pearson BL, Pobbe RL, Bolivar VJ, Blanchard DC and Blanchard RJ. The BTBR T+ tf/J mouse model for autism spectrum disorders-in search of biomarkers. Behav Brain Res 2013; 251: 25-34.
-
(2013)
Behav Brain Res
, vol.251
, pp. 25-34
-
-
Meyza, K.Z.1
Defensor, E.B.2
Jensen, A.L.3
Corley, M.J.4
Pearson, B.L.5
Pobbe, R.L.6
Bolivar, V.J.7
Blanchard, D.C.8
Blanchard, R.J.9
-
6
-
-
76749128438
-
Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP
-
Silverman JL, Tolu SS, Barkan CL and Crawley JN. Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. Neuropsychopharmacology 2010; 35: 976-989.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 976-989
-
-
Silverman, J.L.1
Tolu, S.S.2
Barkan, C.L.3
Crawley, J.N.4
-
7
-
-
84896279364
-
Enhancement of inhibitory neurotransmission by GABAA receptors having alpha2,3-subunits ameliorates behavioral deficits in a mouse model of autism
-
Han S, Tai C, Jones CJ, Scheuer T and Catterall WA. Enhancement of inhibitory neurotransmission by GABAA receptors having alpha2,3-subunits ameliorates behavioral deficits in a mouse model of autism. Neuron 2014; 81: 1282-1289.
-
(2014)
Neuron
, vol.81
, pp. 1282-1289
-
-
Han, S.1
Tai, C.2
Jones, C.J.3
Scheuer, T.4
Catterall, W.A.5
-
8
-
-
84987657081
-
The effects of aging on the BTBR mouse model of autism spectrum disorder
-
Jasien JM, Daimon CM, Wang R, Shapiro BK, Martin B and Maudsley S. The effects of aging on the BTBR mouse model of autism spectrum disorder. Front Aging Neurosci 2014; 6: 225.
-
(2014)
Front Aging Neurosci
, vol.6
, pp. 225
-
-
Jasien, J.M.1
Daimon, C.M.2
Wang, R.3
Shapiro, B.K.4
Martin, B.5
Maudsley, S.6
-
9
-
-
33846921789
-
Autism spectrum disorders: developmental disconnection syndromes
-
Geschwind DH and Levitt P. Autism spectrum disorders: developmental disconnection syndromes. Curr Opin Neurobiol 2007; 17: 103-111.
-
(2007)
Curr Opin Neurobiol
, vol.17
, pp. 103-111
-
-
Geschwind, D.H.1
Levitt, P.2
-
10
-
-
0242300623
-
Postnatal neurodevelopmental disorders: meeting at the synapse?
-
Zoghbi HY. Postnatal neurodevelopmental disorders: meeting at the synapse? Science 2003; 302: 826-830.
-
(2003)
Science
, vol.302
, pp. 826-830
-
-
Zoghbi, H.Y.1
-
11
-
-
33748998205
-
Fragile X syndrome and autism at the intersection of genetic and neural networks
-
Belmonte MK and Bourgeron T. Fragile X syndrome and autism at the intersection of genetic and neural networks. Nat Neurosci 2006; 9: 1221-1225.
-
(2006)
Nat Neurosci
, vol.9
, pp. 1221-1225
-
-
Belmonte, M.K.1
Bourgeron, T.2
-
12
-
-
84907598831
-
Sensory integration in mouse insular cortex reflects GABA circuit maturation
-
Gogolla N, Takesian AE, Feng G, Fagiolini M and Hensch TK. Sensory integration in mouse insular cortex reflects GABA circuit maturation. Neuron 2014; 83: 894-905.
-
(2014)
Neuron
, vol.83
, pp. 894-905
-
-
Gogolla, N.1
Takesian, A.E.2
Feng, G.3
Fagiolini, M.4
Hensch, T.K.5
-
13
-
-
84908702335
-
Structural plasticity: mechanisms and contribution to developmental psychiatric disorders
-
Bernardinelli Y, Nikonenko I and Muller D. Structural plasticity: mechanisms and contribution to developmental psychiatric disorders. Front Neuroanat 2014; 8: 123.
-
(2014)
Front Neuroanat
, vol.8
, pp. 123
-
-
Bernardinelli, Y.1
Nikonenko, I.2
Muller, D.3
-
14
-
-
79951960867
-
Dendritic spine pathology in neuropsychiatric disorders
-
Penzes P, Cahill ME, Jones KA, VanLeeuwen JE and Woolfrey KM. Dendritic spine pathology in neuropsychiatric disorders. Nat Neurosci 2011; 14: 285-293.
-
(2011)
Nat Neurosci
, vol.14
, pp. 285-293
-
-
Penzes, P.1
Cahill, M.E.2
Jones, K.A.3
VanLeeuwen, J.E.4
Woolfrey, K.M.5
-
15
-
-
84907220674
-
Synaptic proteins and receptors defects in autism spectrum disorders
-
Chen J, Yu S, Fu Y and Li X. Synaptic proteins and receptors defects in autism spectrum disorders. Front Cell Neurosci 2014; 8: 276.
-
(2014)
Front Cell Neurosci
, vol.8
, pp. 276
-
-
Chen, J.1
Yu, S.2
Fu, Y.3
Li, X.4
-
16
-
-
0028535113
-
Anatomy and physiology of glutamate in the CNS
-
Greenamyre JT and Porter RH. Anatomy and physiology of glutamate in the CNS. Neurology 1994; 44: S7-13.
-
(1994)
Neurology
, vol.44
, pp. S7-S13
-
-
Greenamyre, J.T.1
Porter, R.H.2
-
17
-
-
0028535070
-
The role of glutamate in epilepsy and other CNS disorders
-
Meldrum BS. The role of glutamate in epilepsy and other CNS disorders. Neurology 1994; 44: S14-23.
-
(1994)
Neurology
, vol.44
, pp. S14-S23
-
-
Meldrum, B.S.1
-
18
-
-
80055102539
-
Quantifying synapses: an immunocytochemistry-based assay to quantify synapse number
-
Ippolito DM and Eroglu C. Quantifying synapses: an immunocytochemistry-based assay to quantify synapse number. J Vis Exp 2010. pii: 2270.
-
(2010)
J Vis Exp
-
-
Ippolito, D.M.1
Eroglu, C.2
-
19
-
-
13544273916
-
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
-
Christopherson KS, Ullian EM, Stokes CC, Mullowney CE, Hell JW, Agah A, Lawler J, Mosher DF, Bornstein P and Barres BA. Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis. Cell 2005; 120: 421-433.
-
(2005)
Cell
, vol.120
, pp. 421-433
-
-
Christopherson, K.S.1
Ullian, E.M.2
Stokes, C.C.3
Mullowney, C.E.4
Hell, J.W.5
Agah, A.6
Lawler, J.7
Mosher, D.F.8
Bornstein, P.9
Barres, B.A.10
-
20
-
-
84858963873
-
Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors
-
Wei H, Chadman KK, McCloskey DP, Sheikh AM, Malik M, Brown WT and Li X. Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors. Biochim Biophys Acta 2012; 1822: 831-842.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 831-842
-
-
Wei, H.1
Chadman, K.K.2
McCloskey, D.P.3
Sheikh, A.M.4
Malik, M.5
Brown, W.T.6
Li, X.7
-
22
-
-
0023370658
-
Calcium-dependent and-independent release of glutamate from synaptosomes monitored by continuous fluorometry
-
Nicholls DG, Sihra TS and Sanchez-Prieto J. Calcium-dependent and-independent release of glutamate from synaptosomes monitored by continuous fluorometry. J Neurochem 1987; 49: 50-57.
-
(1987)
J Neurochem
, vol.49
, pp. 50-57
-
-
Nicholls, D.G.1
Sihra, T.S.2
Sanchez-Prieto, J.3
-
23
-
-
33646150903
-
High throughput analysis of endogenous glutamate release using a fluorescence plate reader
-
Sim AT, Herd L, Proctor DT, Baldwin ML, Meunier FA and Rostas JA. High throughput analysis of endogenous glutamate release using a fluorescence plate reader. J Neurosci Methods 2006; 153: 43-47.
-
(2006)
J Neurosci Methods
, vol.153
, pp. 43-47
-
-
Sim, A.T.1
Herd, L.2
Proctor, D.T.3
Baldwin, M.L.4
Meunier, F.A.5
Rostas, J.A.6
-
24
-
-
84855341900
-
SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism
-
Durand CM, Perroy J, Loll F, Perrais D, Fagni L, Bourgeron T, Montcouquiol M and Sans N. SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism. Mol Psychiatry 2012; 17: 71-84.
-
(2012)
Mol Psychiatry
, vol.17
, pp. 71-84
-
-
Durand, C.M.1
Perroy, J.2
Loll, F.3
Perrais, D.4
Fagni, L.5
Bourgeron, T.6
Montcouquiol, M.7
Sans, N.8
-
25
-
-
0022260733
-
Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes
-
Hollingsworth EB, McNeal ET, Burton JL, Williams RJ, Daly JW and Creveling CR. Biochemical characterization of a filtered synaptoneurosome preparation from guinea pig cerebral cortex: cyclic adenosine 3':5'-monophosphate-generating systems, receptors, and enzymes. J Neurosci 1985; 5: 2240-2253.
-
(1985)
J Neurosci
, vol.5
, pp. 2240-2253
-
-
Hollingsworth, E.B.1
McNeal, E.T.2
Burton, J.L.3
Williams, R.J.4
Daly, J.W.5
Creveling, C.R.6
-
26
-
-
33749531024
-
Rapid isolation of synaptoneurosomes and postsynaptic densities from adult mouse hippocampus
-
Villasana LE, Klann E and Tejada-Simon MV. Rapid isolation of synaptoneurosomes and postsynaptic densities from adult mouse hippocampus. J Neurosci Methods 2006; 158: 30-36.
-
(2006)
J Neurosci Methods
, vol.158
, pp. 30-36
-
-
Villasana, L.E.1
Klann, E.2
Tejada-Simon, M.V.3
-
27
-
-
84907987626
-
Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
-
Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, Goldman J and Sulzer D. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron 2014; 83: 1131-1143.
-
(2014)
Neuron
, vol.83
, pp. 1131-1143
-
-
Tang, G.1
Gudsnuk, K.2
Kuo, S.H.3
Cotrina, M.L.4
Rosoklija, G.5
Sosunov, A.6
Sonders, M.S.7
Kanter, E.8
Castagna, C.9
Yamamoto, A.10
Yue, Z.11
Arancio, O.12
Peterson, B.S.13
Champagne, F.14
Dwork, A.J.15
Goldman, J.16
Sulzer, D.17
-
28
-
-
35448953476
-
Synaptophysin and postsynaptic density protein 95 in the human prefrontal cortex from mid-gestation into early adulthood
-
Glantz LA, Gilmore JH, Hamer RM, Lieberman JA and Jarskog LF. Synaptophysin and postsynaptic density protein 95 in the human prefrontal cortex from mid-gestation into early adulthood. Neuroscience 2007; 149: 582-591.
-
(2007)
Neuroscience
, vol.149
, pp. 582-591
-
-
Glantz, L.A.1
Gilmore, J.H.2
Hamer, R.M.3
Lieberman, J.A.4
Jarskog, L.F.5
-
29
-
-
79957651404
-
Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex
-
Bloss EB, Janssen WG, Ohm DT, Yuk FJ, Wadsworth S, Saardi KM, McEwen BS and Morrison JH. Evidence for reduced experience-dependent dendritic spine plasticity in the aging prefrontal cortex. J Neurosci 2011; 31: 7831-7839.
-
(2011)
J Neurosci
, vol.31
, pp. 7831-7839
-
-
Bloss, E.B.1
Janssen, W.G.2
Ohm, D.T.3
Yuk, F.J.4
Wadsworth, S.5
Saardi, K.M.6
McEwen, B.S.7
Morrison, J.H.8
-
31
-
-
80054889797
-
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication
-
Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, Hof PR and Buxbaum JD. Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication. Mol Autism 2010; 1: 15.
-
(2010)
Mol Autism
, vol.1
, pp. 15
-
-
Bozdagi, O.1
Sakurai, T.2
Papapetrou, D.3
Wang, X.4
Dickstein, D.L.5
Takahashi, N.6
Kajiwara, Y.7
Yang, M.8
Katz, A.M.9
Scattoni, M.L.10
Harris, M.J.11
Saxena, R.12
Silverman, J.L.13
Crawley, J.N.14
Zhou, Q.15
Hof, P.R.16
Buxbaum, J.D.17
-
32
-
-
79955536349
-
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
-
Peca J, Feliciano C, Ting JT, Wang W, Wells MF, Venkatraman TN, Lascola CD, Fu Z and Feng G. Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. Nature 2011; 472: 437-442.
-
(2011)
Nature
, vol.472
, pp. 437-442
-
-
Peca, J.1
Feliciano, C.2
Ting, J.T.3
Wang, W.4
Wells, M.F.5
Venkatraman, T.N.6
Lascola, C.D.7
Fu, Z.8
Feng, G.9
-
33
-
-
77950899212
-
Connecting genes to brain in the autism spectrum disorders
-
Abrahams BS and Geschwind DH. Connecting genes to brain in the autism spectrum disorders. Arch Neurol 2010; 67: 395-399.
-
(2010)
Arch Neurol
, vol.67
, pp. 395-399
-
-
Abrahams, B.S.1
Geschwind, D.H.2
-
34
-
-
79952313620
-
Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting
-
Betancur C. Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still counting. Brain Res 2011; 1380: 42-77.
-
(2011)
Brain Res
, vol.1380
, pp. 42-77
-
-
Betancur, C.1
-
35
-
-
84927178221
-
Disturbed cingulate glutamate metabolism in adults with high-functioning autism spectrum disorder: evidence in support of the excitatory/inhibitory imbalance hypothesis
-
Tebartz van Elst L, Maier S, Fangmeier T, Endres D, Mueller GT, Nickel K, Ebert D, Lange T, Hennig J, Biscaldi M, Riedel A and Perlov E. Disturbed cingulate glutamate metabolism in adults with high-functioning autism spectrum disorder: evidence in support of the excitatory/inhibitory imbalance hypothesis. Mol Psychiatry 2014; 19: 1314-1325.
-
(2014)
Mol Psychiatry
, vol.19
, pp. 1314-1325
-
-
Tebartz van Elst, L.1
Maier, S.2
Fangmeier, T.3
Endres, D.4
Mueller, G.T.5
Nickel, K.6
Ebert, D.7
Lange, T.8
Hennig, J.9
Biscaldi, M.10
Riedel, A.11
Perlov, E.12
-
36
-
-
84880162430
-
Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [(1)H]MRS study
-
Horder J, Lavender T, Mendez MA, O'Gorman R, Daly E, Craig MC, Lythgoe DJ, Barker GJ and Murphy DG. Reduced subcortical glutamate/glutamine in adults with autism spectrum disorders: a [(1)H]MRS study. Transl Psychiatry 2013; 3: e279.
-
(2013)
Transl Psychiatry
, vol.3
-
-
Horder, J.1
Lavender, T.2
Mendez, M.A.3
O'Gorman, R.4
Daly, E.5
Craig, M.C.6
Lythgoe, D.J.7
Barker, G.J.8
Murphy, D.G.9
-
37
-
-
84864398872
-
Elevated glutamatergic compounds in pregenual anterior cingulate in pediatric autism spectrum disorder demonstrated by 1H MRS and 1H MRSI
-
Bejjani A, O'Neill J, Kim JA, Frew AJ, Yee VW, Ly R, Kitchen C, Salamon N, McCracken JT, Toga AW, Alger JR and Levitt JG. Elevated glutamatergic compounds in pregenual anterior cingulate in pediatric autism spectrum disorder demonstrated by 1H MRS and 1H MRSI. PLoS One 2012; 7: e38786.
-
(2012)
PLoS One
, vol.7
-
-
Bejjani, A.1
O'Neill, J.2
Kim, J.A.3
Frew, A.J.4
Yee, V.W.5
Ly, R.6
Kitchen, C.7
Salamon, N.8
McCracken, J.T.9
Toga, A.W.10
Alger, J.R.11
Levitt, J.G.12
-
38
-
-
79952313504
-
Brain growth across the life span in autism: age-specific changes in anatomical pathology
-
Courchesne E, Campbell K and Solso S. Brain growth across the life span in autism: age-specific changes in anatomical pathology. Brain Res 2011; 1380: 138-145.
-
(2011)
Brain Res
, vol.1380
, pp. 138-145
-
-
Courchesne, E.1
Campbell, K.2
Solso, S.3
-
39
-
-
80755130317
-
Neuron number and size in prefrontal cortex of children with autism
-
Courchesne E, Mouton PR, Calhoun ME, Semendeferi K, Ahrens-Barbeau C, Hallet MJ, Barnes CC and Pierce K. Neuron number and size in prefrontal cortex of children with autism. JAMA 2011; 306: 2001-2010.
-
(2011)
JAMA
, vol.306
, pp. 2001-2010
-
-
Courchesne, E.1
Mouton, P.R.2
Calhoun, M.E.3
Semendeferi, K.4
Ahrens-Barbeau, C.5
Hallet, M.J.6
Barnes, C.C.7
Pierce, K.8
-
40
-
-
80052563319
-
Neocortical excitation/inhibition balance in information processing and social dysfunction
-
Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT, Stehfest K, Fudim R, Ramakrishnan C, Huguenard JR, Hegemann P and Deisseroth K. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature 2011; 477: 171-178.
-
(2011)
Nature
, vol.477
, pp. 171-178
-
-
Yizhar, O.1
Fenno, L.E.2
Prigge, M.3
Schneider, F.4
Davidson, T.J.5
O'Shea, D.J.6
Sohal, V.S.7
Goshen, I.8
Finkelstein, J.9
Paz, J.T.10
Stehfest, K.11
Fudim, R.12
Ramakrishnan, C.13
Huguenard, J.R.14
Hegemann, P.15
Deisseroth, K.16
-
41
-
-
0242291090
-
Model of autism: increased ratio of excitation/inhibition in key neural systems
-
Rubenstein JL and Merzenich MM. Model of autism: increased ratio of excitation/inhibition in key neural systems. Genes Brain Behav 2003; 2: 255-267.
-
(2003)
Genes Brain Behav
, vol.2
, pp. 255-267
-
-
Rubenstein, J.L.1
Merzenich, M.M.2
|