Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication

Phytomedicine

Volumn 23, Issue 12, 2016, Pages 1383-1391

  Esposito, Francesca ^a   Carli, Ilaria ^b   Del Vecchio, Claudia ^b   Xu, Lijia ^c   Corona, Angela ^a   Grandi, Nicole ^a   Piano, Dario ^a   Maccioni, Elias ^a   Distinto, Simona ^a   Parolin, Cristina ^b   Tramontano, Enzo ^a,d  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^d Milan Unit   (Italy)

Author keywords

Antiviral activity; Dual inhibitor; HIV 1; Plant extracts; Reverse transcriptase; Sennoside A

Indexed keywords

ALOE EMODIN; ANTHRAQUINONE DERIVATIVE; ANTIVIRUS AGENT; CRYSOPHANOL; DNA POLYMERASE; EFAVIRENZ; EMODIN; INTEGRASE; PHYSCION; PLANT EXTRACT; RHEIN; RHEUM OFFICINALE EXTRACT; RHEUM PALMATUM EXTRACT; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; SENNOSIDE A; SENNOSIDE B; UNCLASSIFIED DRUG; VIRUS DNA; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; P31 INTEGRASE PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; REVERSE TRANSCRIPTASE, HUMAN IMMUNODEFICIENCY VIRUS 1; RNA DIRECTED DNA POLYMERASE INHIBITOR; SENNA EXTRACT; SENNOSIDE A&B;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; CELL ASSAY; CHINESE MEDICINE; CONTROLLED STUDY; DRUG SCREENING; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IN VITRO STUDY; LIFE CYCLE; NONHUMAN; PRIORITY JOURNAL; RHEUM; RHEUM OFFICINALE; RHUBARB; VIRUS MUTATION; VIRUS REPLICATION; CHEMISTRY; DRUG EFFECTS; HIV INFECTIONS; METABOLISM; SPECIES DIFFERENCE; VIROLOGY;

ANTHRAQUINONES; ANTI-HIV AGENTS; HIV INFECTIONS; HIV INTEGRASE; HIV REVERSE TRANSCRIPTASE; HIV-1; MEDICINE, CHINESE TRADITIONAL; PLANT EXTRACTS; REVERSE TRANSCRIPTASE INHIBITORS; RHEUM; RIBONUCLEASE H; SENNA EXTRACT; SPECIES SPECIFICITY; VIRUS REPLICATION;

EID: 84982152610     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2016.08.001     Document Type: Article

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