메뉴 건너뛰기




Volumn 72, Issue 5, 2015, Pages 520-529

The role of vascular endothelial growth factor in neurodegeneration and cognitive decline: Exploring interactions with biomarkers of Alzheimer disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; TAU PROTEIN; VASCULOTROPIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); BIOLOGICAL MARKER; PEPTIDE FRAGMENT; VASCULOTROPIN A;

EID: 84982131470     PISSN: 21686149     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaneurol.2014.4761     Document Type: Article
Times cited : (141)

References (33)
  • 1
    • 0035062394 scopus 로고    scopus 로고
    • The splice variants of vascular endothelial growth factor (VEGF) and their receptors
    • Robinson CJ, Stringer SE. The splice variants of vascular endothelial growth factor (VEGF) and their receptors. J Cell Sci. 2001;114(pt 5):853-865.
    • (2001) J Cell Sci. , vol.114 , pp. 853-865
    • Robinson, C.J.1    Stringer, S.E.2
  • 2
    • 34547941252 scopus 로고    scopus 로고
    • Autocrine VEGF signaling is required for vascular homeostasis
    • Lee S, Chen TT, Barber CL, et al. Autocrine VEGF signaling is required for vascular homeostasis. Cell. 2007;130(4):691-703.
    • (2007) Cell , vol.130 , Issue.4 , pp. 691-703
    • Lee, S.1    Chen, T.T.2    Barber, C.L.3
  • 3
    • 84905089240 scopus 로고    scopus 로고
    • Growth factor and signaling pathways and their relevance to prostate cancer therapeutics
    • Wozney JL, Antonarakis ES. Growth factor and signaling pathways and their relevance to prostate cancer therapeutics. Cancer Metastasis Rev.2014; 33(2-3):581-594.
    • (2014) Cancer Metastasis Rev. , vol.33 , Issue.2-3 , pp. 581-594
    • Wozney, J.L.1    Antonarakis, E.S.2
  • 4
    • 85047694286 scopus 로고    scopus 로고
    • VEGF: A critical player in neurodegeneration
    • Storkebaum E, Carmeliet P. VEGF: a critical player in neurodegeneration. J Clin Invest. 2004;113 (1):14-18.
    • (2004) J Clin Invest. , vol.113 , Issue.1 , pp. 14-18
    • Storkebaum, E.1    Carmeliet, P.2
  • 5
    • 34250864071 scopus 로고    scopus 로고
    • Low serum VEGF levels are associated with Alzheimer's disease
    • Mateo I, Llorca J, Infante J, et al. Low serum VEGF levels are associated with Alzheimer's disease. Acta Neurol Scand. 2007;116(1):56-58.
    • (2007) Acta Neurol Scand. , vol.116 , Issue.1 , pp. 56-58
    • Mateo, I.1    Llorca, J.2    Infante, J.3
  • 6
    • 84906860108 scopus 로고    scopus 로고
    • Reduction in vascular endothelial growth factor expression in the superior temporal, hippocampal, and brainstem regions in Alzheimer's disease
    • Provia J, Jeynes B. Reduction in vascular endothelial growth factor expression in the superior temporal, hippocampal, and brainstem regions in Alzheimer's disease. Curr Neurovasc Res. 2014;11(3): 202-209.
    • (2014) Curr Neurovasc Res. , vol.11 , Issue.3 , pp. 202-209
    • Provia, J.1    Jeynes, B.2
  • 7
    • 84898035954 scopus 로고    scopus 로고
    • Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease
    • Garcia KO, Ornellas FLM, Martin PKM, et al. Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease. Front Aging Neurosci. 2014;6: 30.
    • (2014) Front Aging Neurosci. , vol.6 , pp. 30
    • Garcia, K.O.1    Ornellas, F.L.M.2    Martin, P.K.M.3
  • 8
    • 79961129467 scopus 로고    scopus 로고
    • VEGF-induced angiogenesis ameliorates the memory impairment in APP transgenic mouse model of Alzheimer's disease
    • Wang P, Xie ZH, Guo YJ, et al. VEGF-induced angiogenesis ameliorates the memory impairment in APP transgenic mouse model of Alzheimer's disease. Biochem Biophys Res Commun. 2011;411(3): 620-626.
    • (2011) Biochem Biophys Res Commun , vol.411 , Issue.3 , pp. 620-626
    • Wang, P.1    Xie, Z.H.2    Guo, Y.J.3
  • 9
    • 84891709799 scopus 로고    scopus 로고
    • VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival
    • Religa P, Cao R, Religa D, et al. VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival. Sci Rep. 2013;3:2053.
    • (2013) Sci Rep. , vol.3 , pp. 2053
    • Religa, P.1    Cao, R.2    Religa, D.3
  • 10
    • 0036167595 scopus 로고    scopus 로고
    • Increased intrathecal levels of the angiogenic factors VEGF and TGF-β in Alzheimer's disease and vascular dementia
    • Tarkowski E, Issa R, Sjögren M, et al. Increased intrathecal levels of the angiogenic factors VEGF and TGF-β in Alzheimer's disease and vascular dementia. Neurobiol Aging. 2002;23(2):237-243.
    • (2002) Neurobiol Aging , vol.23 , Issue.2 , pp. 237-243
    • Tarkowski, E.1    Issa, R.2    Sjögren, M.3
  • 11
    • 24944522343 scopus 로고    scopus 로고
    • Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias
    • Blasko I, Lederer W, Oberbauer H, et al. Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias. Dement Geriatr Cogn Disord. 2006;21 (1):9-15.
    • (2006) Dement Geriatr Cogn Disord , vol.21 , Issue.1 , pp. 9-15
    • Blasko, I.1    Lederer, W.2    Oberbauer, H.3
  • 12
    • 84885182452 scopus 로고    scopus 로고
    • Heart-type fatty acid binding protein and vascular endothelial growth factor: Cerebrospinal fluid biomarker candidates for Alzheimer's disease
    • Guo L-H, Alexopoulos P, Perneczky R. Heart-type fatty acid binding protein and vascular endothelial growth factor: cerebrospinal fluid biomarker candidates for Alzheimer's disease. Eur Arch Psychiatry Clin Neurosci. 2013;263(7):553-560.
    • (2013) Eur Arch Psychiatry Clin Neurosci. , vol.263 , Issue.7 , pp. 553-560
    • Guo, L.-H.1    Alexopoulos, P.2    Perneczky, R.3
  • 13
    • 84905254120 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging initiative Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals
    • Paterson RW, Bartlett JW, Blennow K, et al; Alzheimer's Disease Neuroimaging Initiative. Cerebrospinal fluid markers including trefoil factor 3 are associated with neurodegeneration in amyloid-positive individuals. Transl Psychiatry. 2014;4:e419.
    • (2014) Transl Psychiatry , vol.4 , pp. e419
    • Paterson, R.W.1    Bartlett, J.W.2    Blennow, K.3
  • 14
    • 79958102380 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging initiative. Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI
    • Shaw LM, Vanderstichele H, Knapik-Czajka M, et al; Alzheimer's Disease Neuroimaging Initiative. Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI. Acta Neuropathol. 2011;121(5):597-609.
    • (2011) Acta Neuropathol. , vol.121 , Issue.5 , pp. 597-609
    • Shaw, L.M.1    Vanderstichele, H.2    Knapik-Czajka, M.3
  • 15
    • 70350152831 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging initiative. Relationships between biomarkers in aging and dementia
    • Jagust WJ, Landau SM, Shaw LM, et al; Alzheimer's Disease Neuroimaging Initiative. Relationships between biomarkers in aging and dementia.Neurology. 2009;73(15):1193-1199.
    • (2009) Neurology , vol.73 , Issue.15 , pp. 1193-1199
    • Jagust, W.J.1    Landau, S.M.2    Shaw, L.M.3
  • 16
    • 84889600279 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging Initiative effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults
    • Mattsson N, Insel P, Nosheny R, et al; Alzheimer's Disease Neuroimaging Initiative. Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults. Neurobiol Aging. 2014;35(3):614-622.
    • (2014) Neurobiol Aging , vol.35 , Issue.3 , pp. 614-622
    • Mattsson, N.1    Insel, P.2    Nosheny, R.3
  • 17
    • 84871712616 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging initiative development and assessment of a composite score for memory in the Alzheimer's disease neuroimaging initiative (ADNI)
    • Crane PK, Carle A, Gibbons LE, Insel P, Mackin RS, Gross A, et al; Alzheimer's Disease Neuroimaging Initiative. Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI). Brain Imaging Behav.2012;6(4):502-516.
    • (2012) Brain Imaging Behav. , vol.6 , Issue.4 , pp. 502-516
    • Crane, P.K.1    Carle, A.2    Gibbons, L.E.3    Insel, P.4    Mackin, R.S.5    Gross, A.6
  • 18
    • 84871722944 scopus 로고    scopus 로고
    • Alzheimer's Disease neuroimaging initiative a composite score for executive functioning, validated in Alzheimer's disease neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment
    • Gibbons LE, Carle AC, Mackin RS, Harvey D, Mukherjee S, Insel P, et al; Alzheimer's Disease Neuroimaging Initiative. A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment. Brain Imaging Behav. 2012;6(4):517-527.
    • (2012) Brain Imaging Behav. , vol.6 , Issue.4 , pp. 517-527
    • Gibbons, L.E.1    Carle, A.C.2    Mackin, R.S.3    Harvey, D.4    Mukherjee, S.5    Insel, P.6
  • 19
    • 41949137974 scopus 로고    scopus 로고
    • The Alzheimer's Disease neuroimaging initiative (ADNI): MRI methods
    • Jack CR Jr, Bernstein MA, Fox NC, et al. The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods. J Magn Reson Imaging. 2008;27(4):685-691.
    • (2008) J Magn Reson Imaging , vol.27 , Issue.4 , pp. 685-691
    • Jack, C.R.1    Bernstein, M.A.2    Fox, N.C.3
  • 20
    • 0032769093 scopus 로고    scopus 로고
    • Cortical surface-based analysis, I: Segmentation and surface reconstruction
    • Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis, I: segmentation and surface reconstruction.Neuroimage. 1999;9(2):179-194.
    • (1999) Neuroimage , Issue.9 , pp. 179-194
    • Dale, A.M.1    Fischl, B.2    Sereno, M.I.3
  • 21
    • 0032799993 scopus 로고    scopus 로고
    • Cortical surface-based analysis, II: Inflation, flattening, and a surface-based coordinate system
    • Fischl B, Sereno MI, Dale AM. Cortical surface-based analysis, II: inflation, flattening, and a surface-based coordinate system. Neuroimage. 1999;9(2):195-207.
    • (1999) Neuroimage , vol.9 , Issue.2 , pp. 195-207
    • Fischl, B.1    Sereno, M.I.2    Dale, A.M.3
  • 22
    • 0032741345 scopus 로고    scopus 로고
    • High-resolution intersubject averaging and a coordinate system for the cortical surface
    • Fischl B, Sereno MI, Tootell RBH, Dale AM. High-resolution intersubject averaging and a coordinate system for the cortical surface. Hum Brain Mapp. 1999;8(4):272-284.
    • (1999) Hum Brain Mapp. , vol.8 , Issue.4 , pp. 272-284
    • Fischl, B.1    Sereno, M.I.2    Tootell, R.B.H.3    Dale, A.M.4
  • 23
    • 66549127860 scopus 로고    scopus 로고
    • Alzheimer's disease neuroimaging initiative episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects
    • Mormino EC, Kluth JT, Madison CM, et al; Alzheimer's Disease Neuroimaging Initiative. Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects. Brain. 2009;132(pt 5):1310-1323.
    • (2009) Brain , vol.132 , pp. 1310-1323
    • Mormino, E.C.1    Kluth, J.T.2    Madison, C.M.3
  • 24
    • 84861414424 scopus 로고    scopus 로고
    • Within-subject template estimation for unbiased longitudinal image analysis
    • Reuter M, Schmansky NJ, Rosas HD, Fischl B. Within-subject template estimation for unbiased longitudinal image analysis. Neuroimage.2012;61 (4):1402-1418.
    • (2012) Neuroimage , vol.61 , Issue.4 , pp. 1402-1418
    • Reuter, M.1    Schmansky, N.J.2    Rosas, H.D.3    Fischl, B.4
  • 25
    • 33746932485 scopus 로고    scopus 로고
    • An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest
    • Desikan RS, Ségonne F, Fischl B, et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage. 2006;31(3): 968-980.
    • (2006) Neuroimage , vol.31 , Issue.3 , pp. 968-980
    • Desikan, R.S.1    Ségonne, F.2    Fischl, B.3
  • 26
    • 0034978562 scopus 로고    scopus 로고
    • Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
    • Oosthuyse B, Moons L, Storkebaum E, et al. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat Genet. 2001;28 (2):131-138.
    • (2001) Nat Genet , vol.28 , Issue.2 , pp. 131-138
    • Oosthuyse, B.1    Moons, L.2    Storkebaum, E.3
  • 27
    • 0034951235 scopus 로고    scopus 로고
    • Diffusion and perfusion MR imaging in cases of Alzheimer's disease: Correlations with cortical atrophy and lesion load
    • Bozzao A, Floris R, Baviera ME, Apruzzese A, Simonetti G. Diffusion and perfusion MR imaging in cases of Alzheimer's disease: correlations with cortical atrophy and lesion load. AJNR Am J Neuroradiol. 2001;22(6):1030-1036.
    • (2001) AJNR Am J Neuroradiol. , vol.22 , Issue.6 , pp. 1030-1036
    • Bozzao, A.1    Floris, R.2    Baviera, M.E.3    Apruzzese, A.4    Simonetti, G.5
  • 28
    • 0034983181 scopus 로고    scopus 로고
    • Cerebral blood flow and metabolic abnormalities in Alzheimer's disease
    • Matsuda H. Cerebral blood flow and metabolic abnormalities in Alzheimer's disease. Ann Nucl Med. 2001;15(2):85-92.
    • (2001) Ann Nucl Med. , vol.15 , Issue.2 , pp. 85-92
    • Matsuda, H.1
  • 29
    • 77953023118 scopus 로고    scopus 로고
    • The effect of encapsulated VEGF-secreting cells on brain amyloid load and behavioral impairment in a mouse model of Alzheimer's disease
    • Spuch C, Antequera D, Portero A, et al. The effect of encapsulated VEGF-secreting cells on brain amyloid load and behavioral impairment in a mouse model of Alzheimer's disease. Biomaterials. 2010;31(21):5608-5618.
    • (2010) Biomaterials , vol.31 , Issue.21 , pp. 5608-5618
    • Spuch, C.1    Antequera, D.2    Portero, A.3
  • 30
    • 1242338809 scopus 로고    scopus 로고
    • Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer's disease
    • Yang SP, Bae DG, Kang HJ, Gwag BJ, Gho YS, Chae CB. Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer's disease. Neurobiol Aging. 2004;25(3):283-290.
    • (2004) Neurobiol Aging , vol.25 , Issue.3 , pp. 283-290
    • Yang, S.P.1    Bae, D.G.2    Kang, H.J.3    Gwag, B.J.4    Gho, Y.S.5    Chae, C.B.6
  • 31
    • 35748959415 scopus 로고    scopus 로고
    • Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    • Schneider JA, Arvanitakis Z, Bang W, Bennett DA. Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology. 2007;69(24):2197-2204.
    • (2007) Neurology , vol.69 , Issue.24 , pp. 2197-2204
    • Schneider, J.A.1    Arvanitakis, Z.2    Bang, W.3    Bennett, D.A.4
  • 32
    • 34547821883 scopus 로고    scopus 로고
    • Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons
    • Schneider JA, Boyle PA, Arvanitakis Z, Bienias JL, Bennett DA. Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons.Ann Neurol. 2007;62(1):59-66.
    • (2007) Ann Neurol. , vol.62 , Issue.1 , pp. 59-66
    • Schneider, J.A.1    Boyle, P.A.2    Arvanitakis, Z.3    Bienias, J.L.4    Bennett, D.A.5
  • 33
    • 79956084514 scopus 로고    scopus 로고
    • The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on aging-Alzheimer's association workgroups on diagnostic guidelines for Alzheimer's disease
    • Albert MS, DeKosky ST, Dickson D, et al. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3): 270-279.
    • (2011) Alzheimers Dement , vol.7 , Issue.3 , pp. 270-279
    • Albert, M.S.1    DeKosky, S.T.2    Dickson, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.