메뉴 건너뛰기




Volumn 64, Issue 10, 2015, Pages 3564-3572

Reduction in SGLT1 mRNA expression in the ventromedial hypothalamus improves the counterregulatory responses to hypoglycemia in recurrently hypoglycemic and diabetic rats

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; GLUCAGON; GLUCOSE; INSULIN; SHORT HAIRPIN RNA; SODIUM GLUCOSE COTRANSPORTER 1; VIRUS VECTOR; GLUCOSE BLOOD LEVEL; MESSENGER RNA; SLC5A1 PROTEIN, RAT; SMALL INTERFERING RNA;

EID: 84982129778     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0022     Document Type: Article
Times cited : (18)

References (26)
  • 1
    • 0031038124 scopus 로고    scopus 로고
    • Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
    • Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest 1997;99:361-365
    • (1997) J Clin Invest , vol.99 , pp. 361-365
    • Borg, M.A.1    Sherwin, R.S.2    Borg, W.P.3    Tamborlane, W.V.4    Shulman, G.I.5
  • 2
    • 0028296222 scopus 로고
    • Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia
    • Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI. Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest 1994;93:1677-1682
    • (1994) J Clin Invest , vol.93 , pp. 1677-1682
    • Borg, W.P.1    During, M.J.2    Sherwin, R.S.3    Borg, M.A.4    Brines, M.L.5    Shulman, G.I.6
  • 3
    • 0028931891 scopus 로고
    • Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release
    • Borg WP, Sherwin RS, During MJ, Borg MA, Shulman GI. Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release. Diabetes 1995;44:180-184
    • (1995) Diabetes , vol.44 , pp. 180-184
    • Borg, W.P.1    Sherwin, R.S.2    During, M.J.3    Borg, M.A.4    Shulman, G.I.5
  • 4
    • 0032829063 scopus 로고    scopus 로고
    • Hypothalamic glucose sensor: Similarities to and differences from pancreatic beta-cell mechanisms
    • Yang XJ, Kow LM, Funabashi T, Mobbs CV. Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms. Diabetes 1999;48:1763-1772
    • (1999) Diabetes , vol.48 , pp. 1763-1772
    • Yang, X.J.1    Kow, L.M.2    Funabashi, T.3    Mobbs, C.V.4
  • 5
    • 0034855438 scopus 로고    scopus 로고
    • Induction of ependymal, glial, and neuronal transactivation by intraventricular administration of the SGLT1 Na+-D-glucose cotransporter inhibitor phlorizin
    • Briski KP, Marshall ES. Induction of ependymal, glial, and neuronal transactivation by intraventricular administration of the SGLT1 Na+-D-glucose cotransporter inhibitor phlorizin. Neurochem Res 2001;26:783-792
    • (2001) Neurochem Res , vol.26 , pp. 783-792
    • Briski, K.P.1    Marshall, E.S.2
  • 6
    • 0030973372 scopus 로고    scopus 로고
    • Expression of the Na+-D-glucose cotransporter SGLT1 in neurons
    • Poppe R, Karbach U, Gambaryan S, et al. Expression of the Na+-D-glucose cotransporter SGLT1 in neurons. J Neurochem 1997;69:84-94
    • (1997) J Neurochem , vol.69 , pp. 84-94
    • Poppe, R.1    Karbach, U.2    Gambaryan, S.3
  • 7
    • 84907207353 scopus 로고    scopus 로고
    • Transepithelial glucose transport and Na+/K+ homeostasis in enterocytes: An integrative model
    • Thorsen K, Drengstig T, Ruoff P. Transepithelial glucose transport and Na+/K+ homeostasis in enterocytes: an integrative model. Am J Physiol Cell Physiol 2014;307:C320-C337
    • (2014) Am J Physiol Cell Physiol , vol.307 , pp. C320-C337
    • Thorsen, K.1    Drengstig, T.2    Ruoff, P.3
  • 8
    • 0034926379 scopus 로고    scopus 로고
    • Status of glucose transporters in the mammalian kidney and renal development
    • Wallner EI, Wada J, Tramonti G, Lin S, Kanwar YS. Status of glucose transporters in the mammalian kidney and renal development. Ren Fail 2001;23:301-310
    • (2001) Ren Fail , vol.23 , pp. 301-310
    • Wallner, E.I.1    Wada, J.2    Tramonti, G.3    Lin, S.4    Kanwar, Y.S.5
  • 9
    • 0025218676 scopus 로고
    • Effects of glucose, 2-deoxyglucose, phlorizin, and insulin on food intake of lean and fatty rats
    • Tsujii S, Bray GA. Effects of glucose, 2-deoxyglucose, phlorizin, and insulin on food intake of lean and fatty rats. Am J Physiol 1990;258:E476-E481
    • (1990) Am J Physiol , vol.258 , pp. E476-E481
    • Tsujii, S.1    Bray, G.A.2
  • 10
    • 0141532690 scopus 로고    scopus 로고
    • A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line
    • Gribble FM, Williams L, Simpson AK, Reimann F. A novel glucose-sensing mechanism contributing to glucagon-like peptide-1 secretion from the GLUTag cell line. Diabetes 2003;52:1147-1154
    • (2003) Diabetes , vol.52 , pp. 1147-1154
    • Gribble, F.M.1    Williams, L.2    Simpson, A.K.3    Reimann, F.4
  • 11
    • 33845516690 scopus 로고    scopus 로고
    • Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing
    • O'Malley D, Reimann F, Simpson AK, Gribble FM. Sodium-coupled glucose cotransporters contribute to hypothalamic glucose sensing. Diabetes 2006;55:3381-3386
    • (2006) Diabetes , vol.55 , pp. 3381-3386
    • O'Malley, D.1    Reimann, F.2    Simpson, A.K.3    Gribble, F.M.4
  • 12
    • 40749132626 scopus 로고    scopus 로고
    • Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia
    • McCrimmon RJ, Shaw M, Fan X, et al. Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia. Diabetes 2008;57:444-450
    • (2008) Diabetes , vol.57 , pp. 444-450
    • McCrimmon, R.J.1    Shaw, M.2    Fan, X.3
  • 13
    • 80055011903 scopus 로고    scopus 로고
    • Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain
    • Paranjape SA, Chan O, Zhu W, et al. Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain. Am J Physiol Endocrinol Metab 2011;301:E978-E983
    • (2011) Am J Physiol Endocrinol Metab , vol.301 , pp. E978-E983
    • Paranjape, S.A.1    Chan, O.2    Zhu, W.3
  • 14
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-delta delta C (T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-delta delta C (T)) method. Methods 2001;25:402-408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 15
    • 8844260371 scopus 로고    scopus 로고
    • Neurokinin B-producing projection neurons in the lateral stripe of the striatum and cell clusters of the accumbens nucleus in the rat
    • Zhou L, Furuta T, Kaneko T. Neurokinin B-producing projection neurons in the lateral stripe of the striatum and cell clusters of the accumbens nucleus in the rat. J Comp Neurol 2004;480:143-161
    • (2004) J Comp Neurol , vol.480 , pp. 143-161
    • Zhou, L.1    Furuta, T.2    Kaneko, T.3
  • 16
    • 77957608055 scopus 로고    scopus 로고
    • The medial amygdalar nucleus: A novel glucose-sensing region that modulates the counterregulatory response to hypoglycemia
    • Zhou L, Podolsky N, Sang Z, et al. The medial amygdalar nucleus: a novel glucose-sensing region that modulates the counterregulatory response to hypoglycemia. Diabetes 2010;59:2646-2652
    • (2010) Diabetes , vol.59 , pp. 2646-2652
    • Zhou, L.1    Podolsky, N.2    Sang, Z.3
  • 17
    • 77950805120 scopus 로고    scopus 로고
    • Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia
    • Zhu W, Czyzyk D, Paranjape SA, et al. Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia. Am J Physiol Endocrinol Metab 2010;298:E971-E977
    • (2010) Am J Physiol Endocrinol Metab , vol.298 , pp. E971-E977
    • Zhu, W.1    Czyzyk, D.2    Paranjape, S.A.3
  • 18
    • 33745327159 scopus 로고    scopus 로고
    • Blockade of GABA (A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia
    • Chan O, Zhu W, Ding Y, McCrimmon RJ, Sherwin RS. Blockade of GABA (A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia. Diabetes 2006;55:1080-1087
    • (2006) Diabetes , vol.55 , pp. 1080-1087
    • Chan, O.1    Zhu, W.2    Ding, Y.3    McCrimmon, R.J.4    Sherwin, R.S.5
  • 19
    • 48449083962 scopus 로고    scopus 로고
    • Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia
    • Chan O, Cheng H, Herzog R, et al. Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia. Diabetes 2008;57:1363-1370
    • (2008) Diabetes , vol.57 , pp. 1363-1370
    • Chan, O.1    Cheng, H.2    Herzog, R.3
  • 20
    • 79959410500 scopus 로고    scopus 로고
    • Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats
    • Chan O, Paranjape S, Czyzyk D, et al. Increased GABAergic output in the ventromedial hypothalamus contributes to impaired hypoglycemic counterregulation in diabetic rats. Diabetes 2011;60:1582-1589
    • (2011) Diabetes , vol.60 , pp. 1582-1589
    • Chan, O.1    Paranjape, S.2    Czyzyk, D.3
  • 22
    • 34547823399 scopus 로고    scopus 로고
    • Activity-dependent regulation of energy metabolism by astrocytes: An update
    • Pellerin L, Bouzier-Sore AK, Aubert A, et al. Activity-dependent regulation of energy metabolism by astrocytes: an update. Glia 2007;55:1251-1262
    • (2007) Glia , vol.55 , pp. 1251-1262
    • Pellerin, L.1    Bouzier-Sore, A.K.2    Aubert, A.3
  • 23
    • 0031731776 scopus 로고    scopus 로고
    • Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle
    • Pellerin L, Pellegri G, Bittar PG, et al. Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle. Dev Neurosci 1998;20:291-299
    • (1998) Dev Neurosci , vol.20 , pp. 291-299
    • Pellerin, L.1    Pellegri, G.2    Bittar, P.G.3
  • 24
    • 0345074150 scopus 로고    scopus 로고
    • Effect of hypoglycemia on brain glycogen metabolism in vivo
    • Choi IY, Seaquist ER, Gruetter R. Effect of hypoglycemia on brain glycogen metabolism in vivo. J Neurosci Res 2003;72:25-32
    • (2003) J Neurosci Res , vol.72 , pp. 25-32
    • Choi, I.Y.1    Seaquist, E.R.2    Gruetter, R.3
  • 25
    • 0141481875 scopus 로고    scopus 로고
    • Glycogen: The forgotten cerebral energy store
    • Gruetter R. Glycogen: the forgotten cerebral energy store. J Neurosci Res 2003;74:179-183
    • (2003) J Neurosci Res , vol.74 , pp. 179-183
    • Gruetter, R.1
  • 26
    • 66649128152 scopus 로고    scopus 로고
    • Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo
    • Jiang L, Herzog RI, Mason GF, et al. Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo. Diabetes 2009;58:1266-1274
    • (2009) Diabetes , vol.58 , pp. 1266-1274
    • Jiang, L.1    Herzog, R.I.2    Mason, G.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.